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API Palonosetron Hydrochloride

Name: API Palonosetron Hydrochloride
Brand: Hyper Chem
SKU: pr2410111405
Price: 165 USD
Availability: InStock

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CAS No.:

135729-62-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

Hyper Chem

Packaging:

20kg/Drum,25kg/Drum

Price valid (until):

2024-11-11

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Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

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Product Description
Seller Information
Inquiry History

Description

Name	Palonosetron Hydrochloride
CAS number	135729-62-3
Synonym	RS 25233-197; RS25233-197; RS-25233-197; RS25233-198; RS-25233-198; RS 25233-198; RS-25259-197; Palonosetron hydrochloride; US brand name: Aloxi.
Related CAS #	135729-62-3 (HCl); 135729-61-2 (free base)
Description	Palonosetron Hydrochloride: An Important Antiemetic Drug Uses Palonosetron hydrochloride is primarily used for the prevention and treatment of nausea and vomiting. It is especially effective in cases caused by chemotherapy, radiotherapy, and surgery. Mechanism of action: It acts by selectively binding to and blocking 5-hydroxytryptamine type 3 (5-HT3) receptors. By doing so, it inhibits the transmission of signals that trigger nausea and vomiting. Dosage and administration The dosage of palonosetron hydrochloride depends on several factors including the specific treatment regimen, the patient's condition, and body weight. It is usually administered intravenously. Side effects Common side effects may include headache, constipation, and dizziness. In some cases, patients may experience less common but more serious side effects such as abnormal heart rhythms or allergic reactions. Precautions Patients with certain medical conditions such as heart problems, liver or kidney impairment should use palonosetron hydrochloride with caution. It is also important to inform the healthcare provider about all the medications being taken to avoid potential drug interactions. Pregnant and breastfeeding women should consult a doctor before using this drug. In conclusion, palonosetron hydrochloride is a valuable drug in the management of nausea and vomiting. However, its use should be carefully monitored by healthcare professionals to ensure safety and effectiveness.
Structure
Molecular Formula	C₁₉H₂₅ClN₂O
Molecular Weight	332.872
Appearance	Solid powder
Quality Standard	Enterprise standard
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Dry, dark and at 0~4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag
Commercial package	Aluminium Tin, Fiber drum
Origin	China

Certificates

Basic Info

Product Name:

Palonosetron hydrochloride

Other Name:

1H-Benz[de]isoquinolin-1-one,2-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-,hydrochloride (1:1),(3aS)-;1H-Benz[de]isoquinolin-1-one,2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-,monohydrochloride,[S-(R*,R*)]-;1H-Benz[de]isoquinolin-1-one,2-(3S)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-,monohydrochloride,(3aS)-;RS 25259-197;Palonosetron hydrochloride;Aloxi;Onicit;1021481-16-2

CAS No.:

135729-62-3

Molecular Formula:

C19H24N2O.ClH

InChIKeys:

InChIKey=OLDRWYVIKMSFFB-SSPJITILSA-N

Molecular Weight:

332.86800

Exact Mass:

332.16600

HScode:

2933990090

Categories:

Antiemetics

Characteristics

PSA:

23.55000

XLogP3:

3.33430

Appearance:

White Solid

Melting Point:

>290ºC

Boiling Point:

470.4ºC at 760 mmHg

Flash Point:

209.5ºC

Vapor Pressure:

5.07E-09mmHg at 25°C

See More Palonosetron hydrochloride Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Palonosetron hydrochloride Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Certifications:
Certification Report by Bureau Veritas

About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
Taiwan, China	Palonosetron hydrochloride	38 G	Nov 21, 2023

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