L-5-Methyltetrahydrofolate Calcium

  COA:

Product Introduction:
This product is a calcium salt of L-5-methyltetrahydrofolate, belonging to the folic acid group vitamin (vitamin B9, folic acid), which is a coenzyme form of folic acid. L-5-methyltetrahydrofolate calcium (5-mthChemicalbookf) is a naturally occurring salt forming methyl derivative form of folic acid. 5-mthf is also known as L-methylfolic acid, which is the most biologically active and functional form of folic acid and is more easily absorbed than ordinary folic acid.

Lack of folic acid can reduce the ability of cells to synthesize and repair DNA. Supplementing folic acid may be a more beneficial method to increase folic acid, reduce homocysteine levels, and support normal cell proliferation, vascular endothelial function. Cardiovascular disease, nervous system function, and especially 5-MTHF supplementation during pregnancy have been shown to reduce the risk of neural tube abnormalities and recurrence.

Metabolic Pathway

The only form of free folic acid present in human plasma and cells is 5-mthf. Folic acid deficiency is usually due to vitamin deficiency leading to insufficient absorption. During pregnancy, lactation, and child growth, the need for Chemicalbook folic acid is increased. Under the influence of absorption or metabolic changes or drugs, consuming folic acid rich foods cannot guarantee the dose provided, so supplementation is necessary.

Mechanism of action

The biochemical pathway of bioactive folic acid involves a series of enzymatic reactions and cofactors. The absorbed folic acid is reduced and methylated to 5-MTHF during the metabolism of intestinal mucosal cells. "This transition is limited and does not alter the presence of folic acid in the blood circulation, which is subsequently converted to s-adenosylmethionine (SAMe), and the methyl donor is involved in many biochemical processes.". It can also be used as a donor to participate in the synthesis of nucleotides and support biosynthetic DNA.

Biological activity

Levomefolatecacium is an artificial form of folic acid that resists the effects of folic acid.

SOURCEHERB Advantage:
Hangzhou Source Herb Biotechnology Co., Ltd. is a biotechnology company located in Hangzhou, China, focusing on the research and development of natural plant extracts and functional ingredients, providing plant extracts, natural pigments, plant proteins and other products and technical services.

The company's products are widely used in health products, food, cosmetics, medicine, agriculture and other fields. The company has a professional research and development team, as well as modern production equipment and laboratories. The company is committed to research and develop green, natural and healthy products, and actively promote the development of health industry.

Hangzhou Source Herb Biotechnology Co., Ltd. focuses on technical innovation and quality control, and has passed ISO22000 quality management system certification and HACCP food safety management system certification to ensure product quality and safety. At the same time, the company also actively participates in social public welfare undertakings and pays attention to environmental protection and sustainable development.

Product Function:
L-5-methyltetrahydrofolate (along with vitamin B12) plays a role as a methyl donor in a range of metabolic and nervous system processes, making it crucial for many metabolic pathways in the body. L-5-methyltetrahydrofolate plays a crucial role in methylation, converting homocysteine to methionine, producing serotonin and melatonin, and indirectly participating in DNA synthesis.

Studies have shown that neural tube defects in preterm women are associated with an increased risk of miscarriage. This is why it is now recommended to supplement folic acid before and during pregnancy, while increasing the intake of folic acid rich foods.

L-5-methyltetrahydrofolate is the strongest dietary folic acid. It is the only natural form of folate in our blood circulation, and therefore is a type of folate that is typically transported to peripheral tissue for cellular metabolism. Many people do not know that folic acid is a synthetic form of vitamins, which means it only exists in fortified foods and supplements. It is the most severely oxidized form of folic acid and does not possess the coenzyme activity required by the body. Therefore, it must be reduced and methylated in order to metabolize actively in the body. Within cells, folic acid is reduced to the metabolically active form of "tetrahydrofolate".

FAQ:

1. What's the MOQ?

Generally the MOQ is 1kg, Best 25KG/DRUM

1. Is there any discount?

Yes, we will give you the best discount according to the size of your order!

1. How can I confirm the product quality before placing orders?

We will send you the existing sample or prepare the sample according to your request and send it to you for your confirmation！

1. How do you treat quality complaint?

If the quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately！

1. How to contact with us ?

Through SKYPE, WHATSAPP, WeChat, and E-mail.

1. How to place an order & payment ?

(1). Conduct product consultation,

(2). Determine the sample,

(3).After the sample quality meets the requirements, send us the PO,

(4). We reply to PI

(5). The customer completes the payment,

(6). Receive payment for goods, export products,

(7). The customer receives the goods and completes the order.

Cooperative customers:

Our products are exported to European and American countries.

It also has a large customer base in Southeast Asia and other regions.

After-sale service:

If the quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately！

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