Hexapeptide-10/Serilesine CAS 146439-94-3 Cosmetic Peptides

Product Name  Hexapeptide-10
Alias Serilesine
CAS 146439-94-3
Molecular Formula C28H53N7O8
Molecular Weight 615.76
Source synthetic
Purity 95%
Grade Cosmetic Grade
Appearance white Powder
Storage Common storage 2-8ºC, long time storage -20ºC.
Solubility slightly soluble in water
Shelf Life Shelf Life
Specification 1g, 10g, 100g, 1 kg, 10 kg, or as your requirement
Transport Package Aluminium Foil Bag, Bottle or Fiber Can
Origin China
Shipping Methods FedEx, DHL, EMS, Hkems, TNT, Usps, UPS etc.
Function skin repair,  promotes the rebuilding of collagens and helps reduce fine lines and pore size.

What is Hexapeptide-10?

 Hexapeptide-10 is a synthetic peptide containing Alanine, Isoleucine, Lysine, Serine and Valine residues. It increases the synthesis of laminin V and α6-integrin to promote cell binding, with extraordinary visible skin restructuring and firming abilities.

 Hexapeptide-10 promotes the rebuilding of collagens and helps reduce fine lines and pore size. It is a firming active that strengthens the dermo-epidermal junction

The Hexapeptide-10 corresponds to residues 2099-2104 of the laminin α1 chain. Hexapeptide-10 has been shown to modulate tumor invasion, metastasis and angiogenesis. It also induced the synthesis of prostaglandin E2, interstitial collagenase, and gelatinase B in monocyte cell cultures. Laminin fragments containing the SIKVAV sequence may contribute to the inflammatory response at sites of wound healing. They may also play a role in the excessive induction of metalloproteinases in chronic inflammatory lesions.

Hexapeptide-10 is from an adhesion sequence of laminin, which restores the cutaneous structure.Hexapeptide-10 is a firming active that promotes a double-cellular activity on both keratinocytes and fibroblast. It increases the synthesis of laminin-5, alpha6-integrin and hemidesmosomes, thus strengthening the dermal-epidermal junction. With Hexapeptide-10,the skin is restructured, replenished, firmer and more elastic, recovering its fullness.

Function and Application
Crease the synthesis of laminin V and alpha - 6 integrin, promote cells.Cell membrane, and matrix and the combination of
cells to ensure the firming skin.In the skin cell, strengthens the skin nutrition and health, promote skin microcirculation, to
achieve the purpose of reshaping and firming skin.