100% Safe customs clearance high quality Clemastine fumarate CAS 14976-57-9 with Best Price raw material
14976-57-9
Pharmaceutical Grade
99%
shenzhen
1kg/bag;25kg/Cardboard Drum
Yes
2024-12-25
Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10
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Product Details
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Seller Information
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DescriptionECHEMI Editorial ReferenceClemastine Fumarate is a selective histamine H1 receptor antagonist with IC50 of 3 nM.Target: Histamine H1 ReceptorClemastine Fumarate inhibits histamine induced rise in [Ca2+]i in HL-60 cells with an IC50 of 3 nM as compared with that of chlorpheniramine or diphenhydramine with IC50 values of 20 nM and 100 nM, respectively [1]. Clemastine showed a first-pass reduction in the extent of absorption, with oral bioavailability calculated as 39.2 +/- 12.4%. Extravascular distribution of drugBasic Info
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Product Name:
Clemastine fumarate
Other Name:Pyrrolidine,2-[2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methyl-,(2R)-,(2E)-2-butenedioate (1:1);Pyrrolidine,2-[2-[(p-chloro-α-methyl-α-phenylbenzyl)oxy]ethyl]-1-methyl-,(+)-,fumarate (1:1);Pyrrolidine,2-[2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methyl-,[R-(R*,R*)]-,(E)-2-butenedioate (1:1);HS 592;Tavegil;(+)-2-[2-[(p-Chloro-α-methyl-α-phenylbenzyl)oxy]ethyl]-1-methylpyrrolidine fumarate;Clemastine fumarate;Clemastine hydrogen fumarate;Tavegyl;Agasten;Tavist;Meclastine fumarate;Mecloprodine;Telgin G;Lacretin;Kinotomin;Marsthine;Masletine;Inbestan;Lecasol;Maikohis;Piloral;Alphamin;Fuluminol;Mallermin F;Trabest;Xolamin;Anhistan;Aloginan;Reconin;Bravegyl;Telgin;52205-67-1
CAS No.:14976-57-9
Molecular Formula:C21H26ClNO.C4H4O4
InChIKeys:PMGQWSIVQFOFOQ-YKVZVUFRSA-N
Molecular Weight:459.96
Exact Mass:459.181244
EC Number:239-055-2
HScode:2933990090
Categories:
Characteristics-
PSA:
87.1
XLogP3:4.75410
Appearance:white to beige
Density:1.097 g/cm3
Melting Point:177-178 °C
Boiling Point:154 °C @ Press: 0.02 Torr
Flash Point:211ºC
Refractive Index:1.553
Water Solubility:DMSO: soluble 5mg/mL (clear solution; warmed)
Storage Conditions:Store at RT
Vapor Pressure:1.94E-07mmHg at 25°C
Specific rotation:D21 +16.9° (methanol)
Odor:Odorless
Hazard IdentificationClassification of the substance or mixture
Not classified.
GHS label elements, including precautionary statements
Pictogram(s) No symbol. Signal word No signal word
Hazard statement(s) none
Precautionary statement(s) Prevention none
Response none
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10
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Location:
XINYUAN DADUHUI PHASE 1, NO.258 TAOYUAN NORTH ROAD, LIANHU DISTRICT, XI 'AN , SHAANXI CHINA
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Payment Terms:
TT against copy of documents,100% TT in advance
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Average lead Time:
30 days
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2023
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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