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Home > Biochemical Engineering > Inhibitors > Isotretinoin for Sale > 99% purity isotretinoin accutane steroid raw material powder 100% safe and fast delivery
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99% purity isotretinoin accutane steroid raw material powder 100% safe and fast delivery

20 Inquiries

Unit Price: Get Latest Price
CAS No.:

4759-48-2

Grade:

Pesticide Grade

Content:

99%

Port:

QINGDAO

Brand:

QSC=Qingdao Baishiwei Chemical

Packaging:

25kg drum

Price valid (until):

2025-01-24

Company Type:
Trader
Location:
China
Qualification:
Main Products:

ghk cu

  • Product Description

  • Seller Information

  • Inquiry History

  • Description
    Shop China's most professional manufacturer supplies high quality isotretinoin at the best price CAS 4759-48-2-Detailed Image 1


    MF C20H28O2
    MW 300.44
    Boiling Point 381.66°C (rough estimate)
    Density 1.0597 (rough estimate)
    EINECS 225-296-0
    Name Isotretinoin
    Introduction It belongs to the first generation of tretinoin and is the stereoisomer of all trans tretinoin. Oral administration has anti lipid effect and has special curative effect on severe acne. The mechanism of action is as follows: it can reduce the sebaceous glands, inhibit the activity of sebaceous glands, and reduce the secretion of sebaceous glands, so as to inhibit the reproduction of Propionibacterium acnes which depends on the growth of lipid environment. It has the effect of anti keratinization, inhibiting the excessive proliferation of epidermal cells and promoting their differentiation, and can reduce the keratinization of hair follicle mouth and sebaceous duct. It can also affect the function of monocytes and lymphocytes, inhibit the chemotaxis of neutrophils and has anti-inflammatory activity. It selectively binds to retinoic acid chemicalbook nuclear receptor and plays a therapeutic role. It can inhibit the proliferation of Corynebacterium acnes. It has the effect of immunostimulation at low dose and immunosuppression at high dose. It can inhibit the formation of collagenase and gelatinase in skin, and inhibit the activity of ornithine decarboxylase. The induction of ornithine decarboxylase can play a major role in skin mutation, so Accutane can also inhibit the occurrence of tumor. The mechanism of action of this product is similar to that of retinoic acid. It can induce the proliferation of epidermal cells, promote the differentiation of epidermal granular layer into stratum corneum, regulate the process of abnormal keratinization of hair follicle sebaceous epith elium, and play a therapeutic role.

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    Isotretinoin is used primarily for severe cystic acne and acne that has not responded to other treatments Acne treatment usually begins with topical retinoids (e.g., tretinoin, adapalene), in combination with topical antibiotics (e.g., clindamycin, erythromycin) or antiseptics, followed by oral antibiotics (e.g., doxycycline or minocycline). In women a cyproterone acetate-containing contraceptive pill can be useful if there are no contraindications.
     
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    Superiority

    1.High quality and competitive price.
    2.Free sample for your evaluation.
    3.Promptly delivery by well-reputed shipping lines.
    4.We will inform you all the information at every stage in advance.
    5.Packaging can gear to buyers’ special request. 

    Our service

    1. Reply your inquiry in 24 working hours.
    2. Customized design is available. OEM are welcomed.
    3. Exclusive and unique solution can be provided to our customer by our well-trained and professional engineers and
    staff.
    4. As an honest seller, we always use superior raw material, advanced machines, skilled technicians to ensure our products to be finished in high quality and stable feature.

    Why Choose Us?

    1. High-concentration products, strictly control the quality.
    2. Reasonable and flexible price matched with high quality.
    3. Spot samples can be shipped quickly after payment, saving time for receiving goods.
    4.Full experience of large numbers containers loading in Chinese sea port.
    5. Safe raw materials from China.
    6. Have professional customs clearance capabilities and the best after-sales service.


     




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      1. Pharmaceutical Expertise:

      • With years of experience in the pharmaceutical industry, our team brings extensive expertise in product development, manufacturing, and distribution.

      2. High-Quality Products:

      • We adhere to stringent quality control standards and Good Manufacturing Practices (GMP) to ensure the safety and efficacy of our pharmaceutical products.

      3. Diverse Product Range:

      • Our extensive product portfolio includes Active Pharmaceutical Ingredients (APIs), finished dosage forms, pharmaceutical intermediates, and customized pharmaceutical solutions to meet a wide range of needs.

      4. Customization Capabilities:

      • We offer tailored solutions for pharmaceutical product development and manufacturing to meet the unique requirements of our clients.

      5. Global Reach:

      • We have a strong international presence, allowing us to serve customers and partners worldwide. Our products are distributed in various regions, ensuring accessibility and reliability.

      6. Regulatory Compliance:

      • We maintain strict adherence to international regulatory standards and guidelines, ensuring that our products meet all necessary regulatory requirements.

      7. Responsive Customer Support:

      • Our dedicated customer support team is available to assist you promptly with inquiries, orders, and technical support.

      8. Competitive Pricing:

      • We strive to provide competitive pricing for our high-quality pharmaceutical products, enabling cost-effective solutions for our clients.

      9. Sustainable Practices:

      • We are committed to environmentally responsible practices in our manufacturing processes and operations, contributing to a sustainable future.

      10. Innovation and Research: - We invest in research and development to stay at the forefront of pharmaceutical advancements and deliver innovative products to our customers.

      11. Long-Term Partnerships: - We value long-term relationships with our customers and partners, fostering trust and collaboration for mutual success.

      12. Transparent Communication: - We believe in transparent and open communication, ensuring that our clients are informed and confident in their dealings with us.

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    Basic Info
    Product Name:

    Isotretinoin

    Other Name:

    Retinoic acid,13-cis-;13-cis-Retinoic acid;Neovitamin A acid;13-cis-Vitamin A acid;Ro 4-3780;13-cis-β-Retinoic acid;Isotretinoin;(13Z)-Retinoic acid;Accutane;Roaccutane;AGN 190013;Roaccutan;Accure;13-RA;Isotrex;IsotrexGel;cis-Retinoic acid;Absorica;Amnesteem;Claravis;Roacutan

    CAS No.:

    4759-48-2

    Molecular Formula:

    C20H28O2

    InChIKeys:

    InChIKey=SHGAZHPCJJPHSC-XFYACQKRSA-N

    Molecular Weight:

    300.44

    Exact Mass:

    300.44

    EC Number:

    225-296-0

    HScode:

    2942000000

    Categories:

    Inhibitors

    Characteristics
    PSA:

    37.3

    XLogP3:

    5.66

    Appearance:

    Yellow-orange to orange Fine Crystalline Powder

    Density:

    1.0±0.1 g/cm3

    Melting Point:

    174-175 °C

    Boiling Point:

    462.8°C at 760 mmHg

    Flash Point:

    350.6±11.0 °C

    Refractive Index:

    1.556

    Water Solubility:

    H2O: insoluble

    Storage Conditions:

    −20°C

    Vapor Pressure:

    1.02X10-7 mm Hg at 25 °C (est)

    Toxicity:

    LD50 (20 day) in mice, rats (mg/kg): 904, 901 i.p.; 3389, >4000 orally (Kamm)

    PKA:

    ~4

    Hazard Identification

    Classification of the substance or mixture

    Reproductive toxicity, Category 1B

    Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H360 May damage fertility or the unborn child

    H400 Very toxic to aquatic life

    H410 Very toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P273 Avoid release to the environment.

    Response

    P318 IF exposed or concerned, get medical advice.

    P391 Collect spillage.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    PRECAUTIONS FOR CYTOTOXIC AND HAZARDOUS DRUGS:/ Facilities (eg, shelves, carts, counters, and trays) for storing hazardous drugs are designed to prevent breakage and to limit contamination in the event of leakage. Bins, shelves with barriers at the front, or other design features that reduce the chance of drug containers falling to the floor should be used. Hazardous drugs requiring refrigeration should be stored separately from nonhazardous drugs in individual bins designed to prevent breakage and to contain leakage.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    ghk cu

    Location:

    No. 33688 Jingshi East Road, High-tech Zone, Jinan City, Shandong Province, Jinan Comprehensive Bonded Zone Customs supervision warehouse supporting office area 101-B3

    Payment Terms:

    100% TT in advance

    Average lead Time:

    120

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2021

  • Inquiry History
    20 Inquiries
    Country Product Purchase Quantity Date Posted
    Croatia

    Isotretinoin 4759-48-2

    10 G Nov 18, 2023
    Germany

    Isotretinoin

    1 KG Jun 26, 2026
    United States

    isotretinoin

    1 KG Apr 8, 2026
    Germany

    Api Powder Isotretinoin 98% Accutane ISOTRETINOIN API POWDER

    10 G Apr 3, 2026
    Australia

    isotretinoin

    10 G Mar 10, 2026
    United States

    Isotretinoin

    1 MT Mar 5, 2026
    Canada

    Isotretinoin

    50 G Feb 19, 2026
    Czech

    Isotretinoin

    30 G Dec 17, 2025
    Denmark

    Isotretinoin powder

    20 G Nov 21, 2025
    Pakistan

    Isotretinoin

    1 KG Oct 27, 2025
    United States

    Isotretinoin

    1 KG Sep 2, 2024
    United States

    Isotretnoin

    1 MT Jul 10, 2026
    United States

    Isotretinoin

    100 G Jan 27, 2026
    Russia

    Isotretinoin Lidose 8 mg, 16 mg, 24 mg, 32 mg

    500 KG Nov 13, 2025
    Czech

    Isotretinoin

    1 KG Nov 8, 2025
    Pakistan

    Isotretinoin

    10000 MG Oct 25, 2025
    Norway

    Isotretinoin powder

    10 G Apr 13, 2025
    France

    High purity isotretinoin powder for cystic acne

    10 G Nov 3, 2024
    Pakistan

    isotretranin

    200 KG Oct 17, 2024
    Ireland

    Isotretinoin powder

    1 KG Feb 28, 2024
    Post an enquiry for this product
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