High Quality TNJONE 99% Purity Aminophylline 317-34-0 HuaMan

whatsapp:+852 9431 6380

Product Description 

What is Aminophylline?

Aminophylline is a compound of the bronchodilator theophylline with in 2:1 ratio.Aminophylline is less potent and
shorter-acting than theophylline. Its most common use is in the treatment of airway obstruction from asthma or COPD

Aminophylline is a drug combination consisting of bronchodilator theophylline and  in 2: 1 ratio. It is a kind of non-selective adenosine receptor blocker, histone deacetylase activator and phosphodiesterase inhibition. It is mainly indicated for the treatment of various kinds of lung diseases including asthma, COPD, chronic bronchitis and emphysema. Aminophylline exerts its effect through the component of theophylline in vivo. Theophylline can relax the smooth muscle of the bronchial airways and pulmonary blood vessels. It can competitively inhibits type III and type IV phosphodiesterase (PDE), which breaks down cyclic AMP in smooth muscle cells, possibly leading to bronchodilation. Theophylline also binds to the adenosine A2B receptor to block the adenosine mediated bronchoconstriction. Furthermore, during the inflammatory states, theophylline can activate the histone deacetylase to prevent transcription of inflammatory genes that require the acetylation of histones to initiate the transcription

Product Name:    Aminophylline
Synonyms:    AMinophylline(Phyllocontin, Truphylline);Theophylline-ethylenediaMin e anhydrous COS;(Theophylline)2 Ethylenediamin e, Theophylline hemiethylenediamin e complex, 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione, cmpd. with 1,2-ethanediamine (2:1);Aminophylline,99%;Theophylline-e;Aminophylline hydrat;AMINOPHYLLINE;THEOPHYLLINE COMPOUND WITH ETHYLENEDIAMIN E
CAS:    317-34-0
MF:    C9H16N6O2
MW:    240.27
EINECS:    206-264-5
Product Categories:    Somopphyllin, Aminocadol, Phyllocontin;Miscellaneous Biochemicals;API's;317-34-0
Mol File:    317-34-0.mol

Product Name	Aminophylline
CAS NO	317-34-0
Appearance	Light yellow Powder
Molecular Formula	C16H24N10O4
Molecular Weight	420.43
Category	API
Specification	99%
Storage	Keep in a cool, dry, dark location
Shelf Life	24 months when properly stored

Name	Aminophylline
CAS NO.	317-34-0
purity	99%
Standard packing material	Bag/Box
Appearance	White Powder
Shelf Life	2Years
storage condition and solubility	Inert atmosphere,Store in freezer, under -20°C; soluble in water.

Product COA 

Item	Standard	Result
Appearance	White or almost white crystalline powder	Almost white crystalline powder
Melting point	152-156°C	154.6-155.1°C
Specific optical rotation	-16° to -19°	-17.5°
Identification	(1)The retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the standard preparation,as obtained in the assay.	Complies
	(2)UV absorption Max. at 266nm.	Complies
	(3)IR spectra is consistent with CRS.	Complies
PH	4.5-6.5	5.7
Chloride	0.02% max	<0.02%
Fluorides	4.8%min	4.9%
Related substances	Individual impurity not more than 0.5%	0.35%
	Total impurities not more than 2.0%	0.76%
Water	0.5% max	0.13%
Residue on ignition	0.1%max	0.06%
Heavy metals	Less than or egual to 20 millionths	Less than20 millionths
Assay(C12H14Cl2FNO4S)	98.0%min	99.0%

Function and Application:

• Aminophylline can be used as dicuretic and the medicine helping to relax the smooth muscle .The aminophylline can relax the bronchus and the smooth muscle of the blood vessel,inhibit the kidney tubules to reabsorb the sodium and the water and enhance the extraction of heart oedema and so on .It is usually used as mono-medicine.It is mainly used in medicine field.

  Mainly used for asthma, bronchial asthma and chronic bronchitis can also be used for acute heart failure, cardiac asthma, and biliary colic, etc.
  Aminophylline is a drug combination consisting of bronchodilator theophylline and ethylenediamin in 2: 1 ratio. It is a kind of non-selective adenosine receptor blocker, histone deacetylase activator and phosphodiesterase inhibition. It is mainly indicated for the treatment of various kinds of lung diseases including asthma, COPD, chronic bronchitis and emphysema. Aminophylline exerts its effect through the component of theophylline in vivo. Theophylline can relax the smooth muscle of the bronchial airways and pulmonary blood vessels. It can competitively inhibits type III and type IV phosphodiesterase (PDE), which breaks down cyclic AMP in smooth muscle cells, possibly leading to bronchodilation. Theophylline also binds to the adenosine A2B receptor to block the adenosine mediated bronchoconstriction. Furthermore, during the inflammatory states, theophylline can activate the histone deacetylase to prevent transcription of inflammatory genes that require the acetylation of histones to initiate the transcription.

Tirzepatide (LY3298176) is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist that is being developed for the treatment of type 2 diabetes. Tirzepatide (LY3298176) shows significantly better efficacy with regard to glucose control and weight loss than do Dulaglutide.

Tirzepatide, also known as LY 3298176, is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. Tirzepatide has a greater affinity to GIP receptors than to GLP-1 receptors, and this dual agonist behavior has been shown to produce greater reductions of hyperglycemia compared to a selective GLP-1 receptor agonist. Signaling studies reported that tirzepatide mimics the actions of natural GIP at the GIP receptor. Tirzepatide was approved for improving blood sugar control in adults with type 2 diabetes, as an addition to diet and exercise.

Appearance: Powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Quality:   Purity above 99%, directly produced by the manufacturer, can accept quality testing, and can also customize any content of powder, liquid, oil, etc.

Transport:   We can accept sea freight, air freight, and express delivery, with a guarantee time of 1-2 weeks and a customs clearance rate of over 99%. Even if the goods are detained, you can resend the freight and I will resend the goods.

Service:   We can provide sterile water for you to directly mix and inject freeze-dried powder. In addition to powder, we also have liquids, water-based agents, oils, tablets, and professional customized synthesis routes. We provide you with professional guidance on product use, product synthesis, and product customization.

Price:   We do not engage in price wars. Firstly, our quality can be guaranteed; Secondly, our transportation efficiency and customs clearance rate can be guaranteed; Thirdly, we will provide you with the highest quality service, in any aspect. If you have any questions, I will have the answer.

HuaMan Bio acquired early mastery of development and manufacturing of peptides, the short chain amino acids linked by peptide bonds that have enabled new generations of small molecule drugs that closely mimic the body's natural pathways. Now HuaMan Bio possesses first-class capabilities to manufacture peptides at industrial scale and in full compliance with the strictest Good Manufacturing Practice (cGMP) standards.pharmaceutical raw materials, food and feed additives, veterinary drugs and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products, "world peace and health" as its responsibility, the company adhering to the "meet all customer requirements for products" as the service concept, Guarantee "provide qualified products" as the service principle, so that you get "God-like" noble shopping enjoyment. Our company has more than 1000 kinds of polypeptides, raw materials inventory, at any time to meet the various needs of customers for products. Is your best partner.

Q1: What's your MOQ?
A:It depends on different products,we can accept sample order or provide free sample for your test.

Q2:How about delivery leadtime?
A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)

Q3: Is there a discount?
A:Different quantity has different discount.

Q4:How to start orders or make payments?
A:Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T.

Q5: How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

Q6. We don't know you at all, how can we trust you?
A: You are always warm welcomed to visit us at any time. Commitment is the No.1 Point of our Enterprise's Value.

Q7.Do you test all your goods before delivery?
A:Yes, we have 100% test before delivery,International Authorized Third-Party Test for the products if you need are highly welcomed.