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Antalarminhydrochloride

Name: Antalarminhydrochloride
Brand: Dideu
SKU: pr2501071090
Price: 2000 USD
Availability: InStock

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CAS No.:

220953-69-5

Grade:

Pharmaceutical Grade

Content:

98%

Port:

Shanghai

Brand:

Dideu

Packaging:

100mg/Vial

Price valid (until):

2025-02-07

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Shaanxi Dideu Medichem Co. Ltd

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

7 days

Qualification:

Main Products:

Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst

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Product Details
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Inquiry History

Description

Our Reference Specification, for more details, pls contact us for COA, MSDS and certification:

Email & Skype: Service@dideu.com Telephone:+86-29-89586680
Mobile:+86-15129568250; Whatsapp&Wechat: +8615129568250

The packaging can be customized. the shipping term can be by sea, by air, and sample or small quantity can be shipped by DHL, FEDEX, EMS and TNT.

a) Free sample can be supplied.

b) Guide our clients by professional knowledge and teach them how to use our product after sales.

c) Accept SGS, BV any other third-party inspection before loading.d) High quality best price Guaranteed

Why do you choose Dideu Industries as your partner?
A) High quality can be guaranteed. Dideu Industries since 1975 are reputed chemical manufacturer and are Certified by ISO 9001;2015 and have GMP certification.Free sample can be arranged before shipment and SGS,BV and other third party inspection company are accepted before loading.For regular customers, we accept L/C 180 Days, D/P,D/A payment term. If there is any quality problem after goods arrive. Dideu Industries will do fully payment refund.
B) Best price can be guaranteed. As Dideu Industries are integrated pharmaceuticals and chemicals producer, the production cost can be controlled and price will be definitely more competitive than China trading companies.
C) Professional enginners from Dideu Industries will give professional usage guide and services after sales.
D) Dideu Industries work 7×24 hours and your request will be processed by our professional staff in different shift period.

Product Detail

Pharmacological Mechanism Research
- In terms of receptor research:
  - Antihistamine Hydrochloride is a typical H1 - histamine receptor antagonist. It is often used as a tool drug in the process of studying the distribution, function, and signal transduction mechanism of histamine receptors. Researchers can determine the density and affinity of histamine H1 receptors in different tissues and cells by observing the binding of Antihistamine Hydrochloride to histamine receptors. For example, in neuroscience research, it is used to study the interaction between histaminergic neurons and other neurons. When it binds to the histamine H1 receptor, it can block the effect of endogenous histamine, thus helping scientists analyze the function of histamine in regulating neurotransmitter release, neuronal excitability, and so on.
- In terms of drug metabolism research:
  - It is used to study the metabolic pathway and kinetics of drugs in the body. Researchers can track the absorption, distribution, metabolism, and excretion of Antihistamine Hydrochloride in the body to understand the effect of drug - metabolizing enzymes (such as the cytochrome P450 enzyme system) on it. This helps to establish a drug - metabolism model and can provide a reference for the metabolism research of other drugs with similar structures. For example, through research, it is found that it is mainly metabolized by certain specific cytochrome P450 enzymes in the liver. These research findings are very important for predicting drug - drug interactions (possible interactions when it is used in combination with other drugs that are metabolized by the same metabolizing enzymes).
Disease Model Research
- In the research of allergy models:
  - It plays an important role in the establishment and research of allergic disease models. It can be used to induce or relieve allergic reactions in experimental animals to better understand the mechanism of allergic reactions. For example, in a mouse model of allergic rhinitis, the mice are first sensitized to produce an allergic reaction, and then Antihistamine Hydrochloride is used for intervention. By observing the pathological changes of the nasal mucosa, the infiltration of inflammatory cells, and the expression level of related cytokines and other indicators in mice, the anti - allergic mechanism of the drug and the change law of the immune system during the allergic reaction are studied.
- In the research of nervous system disease models (related to the sedative effect):
  - Because it has a sedative effect, it is also used in the research of sleep disorders or mood disorder models related to some nervous system diseases. For example, in the research of an anxiety disorder animal model, the effect of Antihistamine Hydrochloride on the anxiety behavior of animals (such as the behavior in the elevated plus - maze) is observed to explore its regulatory effect on the central nervous system. At the same time, in the model of studying the sleep - regulation mechanism, it can be used as an intervention drug to analyze its effect on the sleep - wake cycle and help scientists understand the role of neurotransmitters (such as histamine) in the sleep process.
Research of Lead Compounds in Drug Development
- Its chemical structure can provide inspiration for the development of new anti - histamine drugs and drugs with a sedative effect. Medicinal chemists can take Antihistamine Hydrochloride as a lead compound and modify its chemical structure to optimize the performance of the drug. For example, changing some functional groups in its chemical structure to improve the selectivity of the drug (only target the histamine H1 receptor and reduce non - specific effects on other receptors), reduce side effects (such as reducing central nervous system side effects such as drowsiness), or prolong the action time of the drug. Through these structural modifications and activity - screening studies, it is hoped that safer and more effective anti - histamine and sedative drugs can be developed.

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Basic Info

Product Name:

ANTALARMIN HYDROCHLORIDE

Other Name:

ANTALARMIN HYDROCHLORIDE;N-BUTYL-N-ETHYL-2,5,6-TRIMETHYL-7-(2,4,6-TRIMETHYLPHENYL)-7H-PYRROLOL[2,3-D]PYRIMIDIN-4-AMINE HYDROCHLORIDE;N-Butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolol[2,3-d]pyrimidin-4-aminehydrochloride;N-Butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-aminehydrochloride;7H-Pyrrolo[2,3-d]pyrimidin-4-amine,N-butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-,hydrochloride

CAS No.:

220953-69-5

Molecular Formula:

C24H35ClN4

InChIKeys:

CGDGXEDXEXACKQ-UHFFFAOYSA-N

Molecular Weight:

415.01

Exact Mass:

414.255035

DSSTox ID:

DTXSID00582018

Categories:

CNS Agents

Characteristics

PSA:

XLogP3:

6.69930

Appearance:

off-white solid

Water Solubility:

DMSO: ~24 mg/mL, soluble

Storage Conditions:

2-8°C

See More ANTALARMIN HYDROCHLORIDE Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More ANTALARMIN HYDROCHLORIDE Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst

Location:
https://www.dideu.com/en/

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7 days

Total Annual Revenue:
Above $100 million

Total Employees:
Above 1000

Year of Establishment:
2016

Company Certificates
- ISO Certificate
- REACH
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Inquiry History

4 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Antalarmin Hydrochloride	10 G	Dec 20, 2024
China	Antalarmin	1 G	Mar 4, 2026
United States	ANTALARMIN HYDROCHLORIDE	1 G	Aug 20, 2025
Canada	Antalarmin Hydrochloride	500 MG	Feb 25, 2026

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ANTALARMIN HYDROCHLORIDE, CAS:220953-69-5	Chemical Grade/99	$12-14/KG FOB	Guangzhou Yaoguang Technology Co., Ltd.	Inquiry

Antalarminhydrochloride

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