Best quality CAS 3483-12-3 DL-Dithiothreitol with low price DL-Dithiothreitol CAS 3483-12-3

1. Basic information

Molecular formula: C4H10O2S2

Molecular weight: 154.25

English name: DL - Dithiothreitol（DTT）

2. Physical properties

Appearance: White crystalline or crystalline powder.

Melting point: 42-43 ° C

Boiling point: 125-130 ° C (0.5 mmHg)

Density: 1.33 g/cm ³

Solubility: It is easily soluble in various organic solvents such as water, ethanol, acetone, chloroform, etc. It has good solubility in aqueous solutions, which are acidic.

3. Chemical properties

Reductive: DTT is a strong reducing agent, and the two thiol groups (- SH) in its molecule can provide hydrogen atoms. It can reduce disulfide bonds (- S-S -) and is widely used in biochemistry and organic chemistry to break disulfide bonds in biomolecules such as proteins and peptides. For example, in protein denaturation and refolding experiments, DTT can reduce disulfide bonds in protein molecules to thiol groups, making the protein structure loose and facilitating subsequent experimental operations. The reaction equation is:.

Oxidation reaction: DTT itself is easily oxidized. When it reduces other substances, its two thiol groups are oxidized to form an intramolecular disulfide bond, generating the oxidized DTT (DTT-S-S-DTT). This oxidized product can also be reduced again to DTT under certain conditions (such as adding a reducing agent).

Stability: Relatively stable in air, but its reducibility gradually weakens over time in the presence of oxygen and metal ions, as oxidation reactions occur. In alkaline environments, the stability of DTT is slightly worse than in acidic environments.

4. Purpose

In the field of biochemistry:

In protein chemistry, it is one of the most commonly used reducing agents. Used for protein extraction, purification, and structural research. In protein electrophoresis experiments, adding DTT can fully denature proteins, ensuring that the electrophoresis results can truly reflect the molecular weight and other characteristics of proteins.

In enzymatic research, it is used to maintain the activity of certain enzymes. Some enzymes have thiol groups in their active centers, and DTT can prevent these thiol groups from being oxidized, thereby maintaining enzyme activity.

In nucleic acid research, it can be used to remove disulfide bonds from nucleic acids, such as in some RNA extraction and processing processes.

Biotechnology industry: widely used in fields such as biopharmaceuticals and genetic engineering. In the production process of recombinant proteins, it is used to prevent the formation of disulfide bonds between protein molecules, ensuring the correct folding and activity of the protein.

Packaging Details: 25 kg/bag or as your requirement.
Port: Tianjin/ Qingdao/ Shanghai, etc.
We can ship the samples by air.
Lead Time: Within 15days after receiving the advance payment or original L/C.

XI'AN YI HANG CHEMICAL CO.,LTD was founded in 2002, located in xian City, shannxi, China. We are the high-tech chemical enterprise which specialized in researching, manufacturing and trading for chemical raw materials ,our products widely used in paints, textile, rubber, leather, plastic and so on.

With many years development and operation,we have become the group company for chemical production,we have the owned factory for produce stable quality products with high performance, and the advanced lab to ensure the best quality of each batch products.

We have our strictly quality control in our production, and we have passed ISO9001:2015 Quality Management System Certification and ISO14001 Environment Management System Certification.

Our main products includes Titanium Dioxide, Lithopone, Iron Oxide series, Chrome Oxide Green, Zinc Oxide, Carbon Black, STPP, SHMP, Oxalic Acid, DOP, SLES, and so on.

Q1: Are you manufacturer or trading company?

A1:Manufacturer.

Q2: Can I get some sample?
A2: Yes, usually 10-25g sample for free.

Q3: Is there a discount?
A3: Of course, welcome to contact us. Price would be different based on different quantity. For bulk
quantity, we will have discount for you.

Q4: How long for production and delivery?
A4: Most products we have in stock, sent time:Within 1-3 business days after received payment. Customized products further discussed.

Q5: Do you accept ODM or OEM service?
A5: Yes,we accept ODM and OEM services, ranges: Soft gel, Capsule, Tablet, Sachet, Granule,Private Label service, etc. Please contact us to design your own brand product.

Q6: How to deliver the goods?
A6: ≤50kg ship by FedEx or DHL etc, ≥50kg ship by Air, ≥100kg can be shipped by Sea. If you have special request on delivery, please contact us.

Q7: How to start orders or make payments?
A7:There are two ways for you to confirm order:
1. Proforma invoice with our company bank details will be sent to you once the order confirmed by Email. Pls arrange payment by TT. Goods will be sent after received payment within 1-3 business days.
2. Trade assurance order will be drafted for you through ALIBABA. Pls confirm and pay through Alibaba. Goods will be sent after received payment within 1-3 business days.