High Quality USP Pharmaceutical Raw Powder Bupropion Hydrochloride CAS 31677-93-7 Antidepressive

Bupropion Hydrochloride More Info

Bupropion hydrochloride, commonly known by the brand name Wellbutrin, is a medication primarily used to treat major depressive disorder (MDD) and seasonal affective disorder (SAD). It is also used as a smoking cessation aid under the brand name Zyban. Bupropion acts as a norepinephrine-dopamine reuptake inhibitor (NDRI), increasing the levels of these neurotransmitters in the brain.

Mechanism of Action

Bupropion works by inhibiting the reuptake of norepinephrine and dopamine, which are neurotransmitters involved in mood regulation. This action increases the availability of these neurotransmitters in the synaptic cleft, enhancing neurotransmission and improving mood. Bupropion also has some nicotinic receptor antagonist activity, which may contribute to its effectiveness in smoking cessation.

Applications

Bupropion HCl is used for:
Major Depressive Disorder (MDD): It is used as an antidepressant to treat depression.
Seasonal Affective Disorder (SAD): Bupropion is effective in preventing episodes of depression associated with seasonal changes.
Smoking Cessation: Marketed as Zyban, it helps reduce cravings and withdrawal symptoms associated with quitting smoking.

Safety and Side Effects

Bupropion can cause several side effects:
Common Side Effects:
Dry mouth
Nausea
Headache
Dizziness
Insomnia
Weight loss
Less Common but Serious Side Effects:
Seizures (rare)
Allergic reactions (rare)
Suicidal thoughts or behaviors (especially in children and adolescents)
Psychosis or mania (in patients with bipolar disorder)
Serious side effects require immediate medical attention.

Routes of Administration

Bupropion HCl is administered orally in tablet form.

Pharmacokinetics

Absorption: Bupropion is well absorbed after oral administration, with peak plasma concentrations reached within 3 hours.
Distribution: It has a moderate volume of distribution, indicating distribution into tissues.
Metabolism: Bupropion is metabolized by the liver, primarily by CYP2B6.
Elimination: The half-life of bupropion is approximately 21 hours. It is primarily excreted via urine.

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FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

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Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express  
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Suitable for more than 50kg 
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Suitable for more than 500kg      
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We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders: 
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

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HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.