China Prodessional Factory YI Hang Supply 99% White Solid 1,7-Dimethylxanthine CAS No.:611-59-6

Essential information

Molecular formula: C7H8N4O2

Molecular weight: 180.16

Physical property

Melting point: 294-296 °C (lit.)

Boiling point: 312.97°C (rough estimate)

Density：1.3640 (rough estimate)

Refractive index: 1.6700 (estimate)

Stability：Store sealed at room temperature

Point of flammibility: 9℃

Storage condition: room temp

Solubility: Ethanol: 0.6mg/mL

Pka: pKa 8.5 (Uncertain)

EINECS: 210-271-9

Biological activity:

Paraxanthine, a metabolite of caffeine, inhibits dopaminergic cell death by stimulating Ryanodine receptor channels.

In vitro study

WhenParaxanthine(PX)isappliedtotheculturesforaprolongedperiod,thenumberofTH+neuronsisaugmentedinadose-dependentmanner.TheeffectofParaxanthine,alreadysignificantat100μM,increasesgraduallyandremainsoptimalbetween800and1000μM,at10DIV.CountsofTH+neuronsperformsatdifferentstagesofmaturationoftheculturesindicatethatParaxanthinemostlikelypreventsDAcellloss.GDNF,aprototypicaltrophicfactorforDAneurons,isonlyslightlymoreeffeChemicalbookctivethan800μMParaxanthineinrescuingDAneuronsafter10and16DIVwhenusedatanoptimalconcentrationof20ng/mL.About80%ofcaffeineisN3-demethylatedtoformParaxanthine,UnlikeParaxanthine,caffeineispoorlyeffectiveinprotectingDAneuronsfromdeathForexample,ataconcentrationof800μM,caffeineproducesonlyamodest40%increaseinthenumberofTH+cellsat10DIV,whereasthesameconcentrationofParaxanthineoptimallypromotesDAcellsurvival(169%increase).

Chemical property

1, 7-dimethylxanthine is a chemical compound. It is a white to light yellow odorless crystal that is soluble in water and organic solvents.

1, 7-dimethylxanthine is an alkaline compound that can be oxidized by oxidizing agents to bromate or bromate. It has good thermal stability and is not easy to decompose at high temperatures. It is also a weak base that reacts with strong acids to form salts.

Purpose

It can promote cardiac contractility and cardiac output to treat cardiovascular diseases such as heart failure. It can also be used to treat gout and kidney disease..

Packaging Details: 25 kg/bag or as your requirement.
Port: Tianjin/ Qingdao/ Shanghai, etc.
We can ship the samples by air.
Lead Time: Within 2-3days after receiving the advance payment or original L/C.

XI'AN YI HANG CHEMICAL CO.,LTD was founded in 2002, located in xian City, shannxi, China. We are the high-tech chemical enterprise which specialized in researching, manufacturing and trading for chemical raw materials ,our products widely used in paints, textile, rubber, leather, plastic and so on.

With many years development and operation,we have become the group company for chemical production,we have the owned factory for produce stable quality products with high performance, and the advanced lab to ensure the best quality of each batch products.

We have our strictly quality control in our production, and we have passed ISO9001:2015 Quality Management System Certification and ISO14001 Environment Management System Certification.

Our main products includes Titanium Dioxide, Lithopone, Iron Oxide series, Chrome Oxide Green, Zinc Oxide, Carbon Black, STPP, SHMP, Oxalic Acid, DOP, SLES, and so on.

Q1: Are you manufacturer or trading company?

A1:Manufacturer.

Q2: Can I get some sample?
A2: Yes, usually 10-25g sample for free.

Q3: Is there a discount?
A3: Of course, welcome to contact us. Price would be different based on different quantity. For bulk
quantity, we will have discount for you.

Q4: How long for production and delivery?
A4: Most products we have in stock, sent time:Within 1-3 business days after received payment. Customized products further discussed.

Q5: Do you accept ODM or OEM service?
A5: Yes,we accept ODM and OEM services, ranges: Soft gel, Capsule, Tablet, Sachet, Granule,Private Label service, etc. Please contact us to design your own brand product.

Q6: How to deliver the goods?
A6: ≤50kg ship by FedEx or DHL etc, ≥50kg ship by Air, ≥100kg can be shipped by Sea. If you have special request on delivery, please contact us.

Q7: How to start orders or make payments?
A7:There are two ways for you to confirm order:
1. Proforma invoice with our company bank details will be sent to you once the order confirmed by Email. Pls arrange payment by  TT. Goods will be sent after received payment within 1-3 business days.
2. Trade assurance order will be drafted for you through ALIBABA. Pls confirm and pay through Alibaba. Goods will be sent after  received payment within 1-3 business days.