Adipotide (FTPP) peptide
GMP ISO TDS
Pharmaceutical Grade
99.69%
1
Million
1g 10g 100g 1kg/bag 25kg/Cardboard Drum
Yes
2025-04-20
Avanafil,Tirzepatide,Semaglutide,Pregabalin,Nootropics,MT2
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Product Details
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Seller Information
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DescriptionCertificates
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TDS
Basic Info-
Product Name:
FTPP
Categories:
Research-
Class:
Chimeric peptidomimetic (fat-targeting vascular disruptor)
Status:Research compound — Not FDA approved, clinical development discontinued
Mechanism:A synthetic chimeric peptide composed of a fat-vascular-targeting cyclic peptide (CKGGRAKDC) linked via a GG spacer to a pro-apoptotic peptide (KLAKLAK)2. Adipotide selectively binds prohibitin in the vasculature of white adipose tissue, then delivers the pro-apoptotic domain to induce vascular disruption, causing fat tissue death. In primate studies (2011), it produced significant weight loss (~11%) but also caused renal toxicity, leading to development discontinuation.
Activity note:Adipotide is not a receptor agonist. It functions as a targeted vascular disruptor. Functional activity is measured by tissue-specific apoptosis, not traditional EC50.
Source:PubChem: Adipotide (CID 163360068); Kolonin MG, et al. Sci Transl Med. 2004;6(148):148ra16.DOI
References-
PubChem:Literature:
Sci Transl Med: Kolonin MG, et al. (2004) — Adipotide mechanism; ChemicalBook: Adipotide (CAS 859216-15-2)
Disclaimer:Adipotide is NOT FDA-approved or EMA-approved. It is a research compound only. Clinical development was discontinued due to renal toxicity observed in primate studies. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Avanafil,Tirzepatide,Semaglutide,Pregabalin,Nootropics,MT2
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Location:
Room 1-2208, Lianhecaifu Square, No2177, Tianchen Road, Gaoxin District, Jinan City, Shandong Province, China
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Payment Terms:
L/C,100% TT in advance
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Average lead Time:
3 days
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Total Annual Revenue:
$1 million-$2.5 million
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Total Employees:
11-50
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Year of Establishment:
2012
Company Certificates-
business license
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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