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China origin factory supply Milk Thistle Extract Silymarin UV80%~90% HPLC40%~60% used for liver protection and improving human immunity buy - large image1

China origin factory supply Milk Thistle Extract Silymarin UV80%~90% HPLC40%~60% used for liver protection and improving human immunity buy - image1

China origin factory supply Milk Thistle Extract Silymarin UV80%~90% HPLC40%~60% used for liver protection and improving human immunity

Name: China origin factory supply Milk Thistle Extract Silymarin UV80%~90% HPLC40%~60% used for liver protection and improving human immunity
Brand: HANDOM CHEM
Price: 0.5 USD
Availability: InStock

8 Inquiries

Unit Price: Get Latest Price 

CAS No.:

65666-07-1

Grade:

Food Grade

Content:

80%

Port:

Shanghai or Beijing

Brand:

HANDOM CHEM

Packaging:

50g/Aluminum Foil Bag, 100g/Aluminum Foil Bag, 200g/Aluminum Foil Bag, 500g/Aluminum Foil Bag, 1kg/Aluminum Foil Bag, 5kg/Carton, 10kg/Carton, 20kg/Cardboard Drum or 25kg/Cardboard Drum

Price valid (until):

2025-09-30

Contact Supplier

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DALIAN HANDOM CHEMICALS CO.,LTD.

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

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Product Description
Seller Information
Inquiry History

Description

Product Details

Product Name: Milk Thistle Extract

Extracted From: Silybum marianum (L.) Gaertn.

Plant Background: Milk thistle belongs to the Asteraceae family, native to the Mediterranean, and now distributed worldwide. Its seeds are the source of extraction.

Active Ingredients: The core ingredient is Silymarin (a mixture of flavonoid lignans), of which Silybin accounts for 50%-70% and is the main active substance.

Shop China origin factory supply Milk Thistle Extract Silymarin UV80%~90% HPLC40%~60% used for liver protection and improving human immunity-Detailed Image 1

Brief Introduction:

Milk thistle extract is a compound separated and refined from the whole herb and seeds of the Asteraceae plant Silybum marianum (L.) Gaertn.

Milk thistle is an annual or biennial herb native to southern Europe and North Africa, which has a history of cultivation and use in Europe and Africa for thousands of years. It began to be planted in China in the 1980s and was later planted in large quantities in Shaanxi, Hebei, Jiangsu, Northeast China and other places.

Milk thistle extract is mainly used for liver protection, anti-oxidation and blood sugar regulation.

Mechanism of Action:

1) Antioxidant: Neutralizes free radicals and reduces oxidative stress.

2) Anti-inflammatory: Inhibits inflammatory factors (such as TNF-α, IL-6).

3) Liver Protection: Stabilizes liver cell membranes, promotes liver regeneration, and inhibits damage caused by toxins (such as alcohol and poisonous mushrooms).

Silymarin Extracted by Acetone (CAS No.: 65666-07-1)	UV 80% ~ UV 90%	HPLC 40% ~ HPLC 60%
	UV 80%	HPLC 45%	Silybin & Isosilybin 30%
	UV 80%	HPLC 50%	Silybin 30% (Silybin A+Silybin B)
	UV 85%	HPLC 55%	Silybin 35% (Silybin A+Silybin B)
	UV 85%	HPLC 60%
Silymarin Extracted by Ethanol (CAS No.: 65666-07-1)	UV 80%	HPLC 45%	Silybin & Isosilybin 30%
	UV 80%	HPLC 50%	Silybin 30% (Silybin A+Silybin B)
	UV 85%	HPLC 55%	Silybin 35% (Silybin A+Silybin B)
	UV 85%	HPLC 60%
Silymarin Extracted by Ethyl Acetate (CAS No.: 65666-07-1)	UV 80%	HPLC 45%	Silybin & Isosilybin 30%
	UV 80%	HPLC 50%	Silybin 30% (Silybin A+Silybin B)
	UV 85%	HPLC 55%	Silybin 35% (Silybin A+Silybin B)
	UV 85%	HPLC 60%
Water-Soluble Silymarin (CAS No.: 65666-07-1)	UV 20%
	UV 40%
	UV 45%
Silybin (CAS No.: 22888-70-6)	Silybin 70%
	Silybin 80%
	Silybin 90%
	Silybin 95%
	Silybin 98%
Organic Milk Thistle Extract	UV 70%
Silymarin Granules	1) Silymarin Granules or Milk Thistle Oil Microencapsulated Powder is processed and produced according to the customers' requirements for the particle size of silymarin, which is convenient for customers to directly fill capsules or compress tablets. 2) Conventional Silymarin Powder does not have good fluidity, so Silymarin Granules make up for this shortcoming.
Milk Thistle Oil Microencapsulated Powder

Test Items		Specifications (Silymarin UV 80%)
Appearance		Amorphous powder
Colour		Yellow to yellowish-brown
Odour		Slight, Specific
Solubility	In water	Practically insoluble
Solubility	In Methanol and Acetone	Soluble
Identification		A. Passes TLC Test
Identification		B. Passes HPLC Identification Test
Sulphated Ash		Not more than 0.5%
Heavy Metals		Not more than 10 ppm
Lead (Pb)		Not more than 2.0 ppm
Cadmium (Cd)		Not more than 1.0 ppm
Mercury (Hg)		Not more than 0.1 ppm
Arsenic (As)		Not more than 1.0 ppm
Loss on Drying (2 hours, 105℃)		Not more than 5.0%
Particle Size		95% pass through 80 mesh sieve
Assay of Silymarin (UV test, per cent, Standard in House)		Not less than 80%
Assay of Silymarin (Test by HPLC)
-sum of Silycristin and Silydianin
-sum of Silybin A and Silybin B
-sum of Isosilybin A and Isosilybin B
Residual Solvents	n-Hexane	Not more than 290 ppm
	Acetone	Not more than 5000 ppm
	Ethanol	Not more than 5000 ppm
Pesticide Residues		According to the Standard of USP43<561>
Microbiological Limits	Total Aerobic Microbial Count	Not more than 1000 CFU/g
	Total combined Yeasts & Mould Count	Not more than 100 CFU/g
	Escherichia coli	Negative/g
	Salmonella	Negative/g
	Staphylococcus aureus	Negative/g

Test Items		Specifications (Silybin & Isosilybin 30%)
Appearance		Amorphous powder
Colour		Yellow to yellowish-brown
Odour		Slight, Specific
Solubility	In water	Practically insoluble
Solubility	In Methanol and Acetone	Soluble
Identification		A. Passes TLC Test
Identification		B. Passes HPLC Identification Test
Sulphated Ash		Not more than 0.5%
Heavy Metals		Not more than 10 ppm
Lead (Pb)		Not more than 2.0 ppm
Cadmium (Cd)		Not more than 1.0 ppm
Mercury (Hg)		Not more than 0.1 ppm
Arsenic (As)		Not more than 1.0 ppm
Loss on Drying (2 hours, 105℃)		Not more than 5.0%
Particle Size		95% pass through 80 mesh sieve
Assay of Silymarin (UV test, per cent, Standard in House)		Not less than 80%
Assay of Silymarin (Test by HPLC)
-sum of Silycristin and Silydianin
-sum of Silybin A and Silybin B
-sum of Isosilybin A and Isosilybin B
Residual Solvents	n-Hexane	Not more than 290 ppm
	Acetone	Not more than 5000 ppm
	Ethanol	Not more than 5000 ppm
	Ethyl Acetate	Not more than 5000 ppm
Pesticide Residues		According to the Standard of USP43<561>
Microbiological Limits	Total Aerobic Microbial Count	Not more than 1000 CFU/g
	Total combined Yeasts & Mould Count	Not more than 100 CFU/g
	Escherichia coli	Negative/g
	Salmonella	Negative/g
	Staphylococcus aureus	Negative/g

Test Items		Specifications (Silymarin HPLC 50%)
Appearance		Amorphous powder
Colour		Yellow to yellowish-brown
Odour		Slight, Specific
Solubility	In Water	Practically insoluble
Solubility	In Methanol and Acetone	Soluble
Identification		A. Passes TLC Test
Identification		B. Passes HPLC Identification Test
Sulphated Ash		Not more than 0.5%
Heavy Metals		Not more than 10 ppm
Lead (Pb)		Not more than 2.0 ppm
Cadmium (Cd)		Not more than 1.0 ppm
Mercury (Hg)		Not more than 0.1 ppm
Arsenic (As)		Not more than 1.0 ppm
Loss on Drying (2 hours, 105℃)		Not more than 5.0%
Particle Size		95% pass through 80 mesh sieve
Assay of Silymarin (UV test, per cent, Standard in House)		Not less than 80%
Assay of Silymarin (Test by HPLC)
-sum of Silycristin and Silydianin
-sum of Silybin A and Silybin B
-sum of Isosilybin A and Isosilybin B
Residual Solvents	n-Hexane	Not more than 290 ppm
	Acetone	Not more than 5000 ppm
	Ethanol	Not more than 5000 ppm
Pesticide Residues		According to the Standard of USP43<561>
Microbiological Limits	Total Aerobic Microbial Count	Not more than 1000 CFU/g
	Total combined Yeasts & Mould Count	Not more than 100 CFU/g
	Escherichia coli	Negative/g
	Salmonella	Negative/g
	Staphylococcus aureus	Negative/g

Test Items		Specifications (Water-Soluble Silymarin UV 40%)
Assay of Silymarin (UV test, per cent, Standard in House)		Not less than 40.0%
Appearance		Yellow to yellowish-brown powder
Odour & Taste		Characteristic
Solubility in Water (1g/100mL)		100% soluble
Sulphated Ash		Not more than 0.5%
Loss on Drying (2 hours, 105℃)		Not more than 5.0%
Heavy Metals		Not more than 10 ppm
Lead (Pb)		Not more than 2.0 ppm
Cadmium (Cd)		Not more than 1.0 ppm
Mercury (Hg)		Not more than 0.1 ppm
Arsenic (As)		Not more than 1.0 ppm
Particle Size		95% pass through 80 mesh sieve
Pesticide Residues		According to the Standard of USP43<561>
Microbiological Limits	Total Aerobic Microbial Count	Not more than 1000 CFU/g
	Total combined Yeasts & Mould Count	Not more than 100 CFU/g
	Escherichia coli	Negative/g
	Salmonella	Negative/g
	Staphylococcus aureus	Negative/g

Benefits and Uses of Milk Thistle Extract:

1. Liver Protection:
Milk thistle extract has the effect of protecting liver, mainly due to Silybin and Isosilybin (rich in flavonoids), these ingredients have the ability to resist oxidation and scavenge free radicals, protect liver cell membranes from damage, reduce liver cell damage and induce apoptosis, thereby maintaining the stability of liver cells and the normal physiological function of the liver. Therefore, it is widely used in many kinds of liver protection products.

2. Antioxidant:
Its powerful antioxidant properties can neutralize free radicals and reduce oxidative stress damage to cells, this can help prevent the occurrence of chronic diseases. It can also prevent skin aging, damage and pigmentation, and is used in cosmetics.

3. Regulate Blood Sugar:
Some studies have shown that milk thistle may play a role in improving insulin sensitivity and lowering blood sugar levels, but more research in this area is needed.

4. Anti-inflammatory:
Milk thistle extract has potential anti-inflammatory effects and can help alleviate the symptoms of inflammatory-related diseases. It can also reduce discomfort such as redness, itching and allergies, making the skin more comfortable.

Shop China origin factory supply Milk Thistle Extract Silymarin UV80%~90% HPLC40%~60% used for liver protection and improving human immunity-Detailed Image 2

Packaging:

50g/Aluminum Foil Bag, 100g/Aluminum Foil Bag, 200g/Aluminum Foil Bag, 500g/Aluminum Foil Bag, 1kg/Aluminum Foil Bag, 5kg/Carton, 10kg/Carton, 20kg/Cardboard Drum, 25kg/Cardboard Drum or according to the specific requirements from customers.

Storage Conditions:

Stored in airtight containers in a cool dry place before using; kept away from direct sunlight, heat and moisture.

Shelf Life:

36 months from the date of manufacturing when stored under the above conditions.

Basic Info

Product Name:

Silymarin

Other Name:

Silymarin;Legalon 70;Legalon;Flavobion;Pluropon;Silirex;Silmar;Silarin;Apihepar;Silymarin Group;Silepar;Laragon;Karsilin;Silistrong;Silystrong;Darsil;Silybon

CAS No.:

65666-07-1

InChIKeys:

SEBFKMXJBCUCAI-WAABAYLZSA-N

Molecular Weight:

48244

Exact Mass:

482.121307

EC Number:

613-830-9

UNII:

853OHH1429

DSSTox ID:

DTXSID5023580|DTXSID30858697|DTXSID5031971

NCI Thesaurus Code:

C29261

ATC Code:

A - Alimentary tract and metabolism

HScode:

3003909090

Categories:

Plant Extracts

Characteristics

PSA:

155.14000

XLogP3:

2.59

Appearance:

Yellow and brown powder

Density:

1.5±0.1 g/cm3

Melting Point:

158 °C

Boiling Point:

793.0±60.0 °C at 760 mmHg

Flash Point:

274.5±26.4 °C

Refractive Index:

1.684

Storage Conditions:

−20°C

See More Silymarin Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Silymarin Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

Location:
RM702, Building 21, Liuhe Road, Ganjingzi Dist, Dalian, Liaoning, China

Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15

Total Annual Revenue:
$5 million-$10 million

Total Employees:
51-100

Year of Establishment:
2020

Dalian Handom Chemicals Co., Ltd.(HDC CHEM) is a professional 15-Year-Experienced Supplier of APIs & Intermediates, Pharmaceutical Excipients, Food & Nutraceutical Ingredients, Personal Care Chemicals and Specialty Chemicals from northeast of China, which strives to provide customers with high-quality products and comprehensive service across all over the world, our main products cover Retatrutide Lyophilized Powder, Retatrutide, Tirzepatide, Tirzepatide Lyophilized Powder, Semaglutide, Mazdutide, Cagrilintide, LL-37, Thymosin Alpha 1(Thymosin α1), MT-2, MOTS-c, HEP-1, TB-500, NAD+, GHK-Cu, Glow, Klow, Selank, Semax, Glutathione, 5-Amino-1MQ, ARA-290, SS-31, DSIP, SNAP-8, Medetomidine, Medetomidine Hydrochloride, Salcaprozate Sodium, Sodium 8-(2-hydroxybenzamido)octanoate, 2,6-Dimethyl Beta Cyclodextrin, mPEG-DMG-2K, mPEG-DSPE-2K, 1,2-Distearoyl-sn-3-phosphacholine(DSPC), 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(DOPE), Pharmaceutical Grade Fructose, Lactose Anhydrous, Lactose Monohydrate, Orotic acid anhydrous, Orotic acid monohydrate, 6-Methyluracil, Chitosan, Mushroom Chitosan, Chitosan Hydrochloride, Chitosan Oligosaccharide, Alginate Oligosaccharide, Inulin, L-Serine, Mung Bean Peptide, Walnut Peptide, Rice Peptide, Oyster Peptide, Sea Cucumber Peptide, Hydrolyzed Keratin, Folic Acid, Vitamin E Acetate, Vitamin B2, Riboflavin Sodium Phosphate, Pyridoxal 5'-phosphate Monohydrate, Vegan Vitamin D3, Vitamin A Palmitate, Vitamin A Acetate, Apple Pectin, Citrus Pectin, Sunflower Pectin, Salidroside, Urolithin A, Milk Thistle Extract, Saffron Extract, Red Clover Extract, Sulforaphane, Glucoraphanin, Soy Isoflavones, Soy Lecithin, Soya Lecithin, Egg Yolk Lecithin, Phosphatidylserine, Cooling Agent WS-3, Cooling Agent WS-5, Cooling Agent WS-10, Cooling Agent WS-12, Cooling Agent WS-23, Cooling Agent WS-27, Menthyl Lactate, Menthyl PCA, Avobenzone, Benzophenone-3 (UV-9), Benzophenone-4 (UV-284), Bis-ethylhexyloxyphenol Methoxyphenyl Triazine (Bemotrizinol), Diethylaminohydroxybenzoyl Hexyl Benzoate (UVA Plus), Diethylhexyl Butamido Triazone (Iscotrizinol), Disodium Phenyl Dibenzimidazole Tetrasulfonate (DPDT), Ethylhexyl Triazone (UVT-150), Homosalate, Octocrylene, 2-Ethylhexyl Salicylate (Octyl Salicylate), 2-Ethylhexyl Trans-4-Methoxycinnamate (OMC), 2-Phenylbenzimidazole-5-Sulfonic Acid (UV-T), Lanolin Anhydrous, Palmitoyl Tripeptide-5, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Biotinoyl Tripeptide-1, etc.

Inquiry History

8 Inquiries

Country	Product	Purchase Quantity	Date Posted
Pakistan	Silymarin	150 KG	May 23, 2026
Algeria	SILYMARINE	100 G	Dec 14, 2023
India	Silymarin	200 KG	May 25, 2025
Vietnam	Silymarin	1 KG	Aug 17, 2023
Brazil	SILIMARINA	95.00 KG	Jun 30, 2023
Poland	Silymarin API (Milk Thistle Fruit Dry Extract) ETHYL ACTETATE ONLY!	1000 KG	Mar 19, 2026
Russia	Sylimarin	100 G	Dec 20, 2024
India	Silymarin	5 G	Nov 12, 2024

Post an enquiry for this product

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