MSG(142-47-2)

L-(+)Sodium glutamate

L-Glutamic acid monosodium salt monohydrate,L-2-Aminopentanedioic acid, MSG, Sodium L-glutamate;L-(+)Sodium glutamat;L-Glutamic acid mono;MSG (MONOSODIUM GLUTAMATE);L-SodiuM glutaMate hydrate;sodiumglutamatemonohydrate;vetsin;zest

142-47-2

C5H10NNaO4

LPUQAYUQRXPFSQ-DFWYDOINSA-M

171.13

169.035

205-538-1

H0US799L9M

TSCA listed

DTXSID9020906

white to off-white

29224999

Alcohols, Phenols, Phenol Alcohols

103.45

-1.37130

White crystal powder

d20 (saturated water soln): 1.620

232°C

333.8ºC at 760 mmHg

155.7ºC

25 ° (C=10, 2mol/L HCl)

>=10 g/100 mL at 20 ºC

Keep tightly closed in a cool place in a tightly closed container.

2.55E-05mmHg at 25°C

Although several mechanisms have been proposed to be responsible for causing CRS, none has been extensively studied. One hypothesis has been that the effects are due to an immediate hypersensitivity reaction. Since no immunoglobulin E (IgE)-mediated reaction has been documented, there is no direct evidence that this is the case. Another hypothesis is that vitamin B6 deficiency plays a role in the response because the symptoms were prevented by supplementing individuals with the vitamin. Since glutamate can be converted to acetylcholine by the tricarboxylic acid cycle, it has also been proposed that the effects are due to an increase in acetylcholine levels. It has been noted that after MSG ingestion, there is a decrease in the levels of cholinesterase (the enzyme that breaks down acetylcholine). Due to inadequate investigations, it is not currently known if any or all of these mechanisms are responsible for CRS. The neurotoxicity of MSG has only been demonstrated in rodent species and rabbits after exposure to very large doses. The neurotoxic effect has been attributed to excitotoxicity.

Odorless

Meaty taste comes from contaminants in crude glutamates; sweet-saline taste in large concn; no flavor in small quantity|A 1% concn or more is liable to produce a sweetish taste.

THE MONOHYDRATE FORMS NEEDLES|THE FLAVOR BECOMES PERCEPTIBLE @ A CONCN OF 0.03% IN DISTILLED WATER|Below -8 deg /C/, it crystallizes as a pentahydrate, which, after filtration and exposure to air, loses water of crystallization and becomes the monohydrate.

Water soluble.

Salts, Acidic

L-(+)Sodium glutamate is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Keep in dark place,Inert atmosphere,Room temperature