hope-Colistin sulphate

Colistin Sulphate 

Product Name: Colistin Sulphate
CAS Number: 1264-72-8
Molecular Formula: C₅₈H₁₀₅N₁₆O₂₈S₂ (mixture of cyclic polypeptides))
Grade: Veterinary API 
Appearance: White to pale yellow powder
Standard: USP / EP / BP / CP / In-house
Packaging: 25kg/drum or customized

Product Overview

Colistin Sulphate is a polypeptide antibiotic belonging to the polymyxin group, primarily composed of polymyxin E1 and E2. It exhibits potent bactericidal activity against gram-negative bacteria by disrupting the bacterial cell membrane. Though once used in human medicine, it is now more widely applied in veterinary medicine and feed additives due to resistance concerns in clinical settings.

It is especially effective against Enterobacteriaceae such as E. coli and Salmonella species, making it valuable in livestock and poultry farming to prevent and treat intestinal infections.

Applications

• Veterinary medicine for poultry, pigs, and cattle

• Treatment and prevention of enteric infections caused by gram-negative bacteria

• Commonly used in premix, oral powder, or soluble granule form

• Often combined with other antimicrobials in compound formulations

Key Features

• Strong efficacy against gram-negative pathogens (E. coli, Salmonella, Pseudomonas aeruginosa)

• Poor gastrointestinal absorption, making it ideal for local intestinal treatment

• Low cross-resistance with other antibiotic classes

• Complies with global veterinary pharmacopeial standards

Storage & Handling

Store in a cool, dry, and well-ventilated area. Protect from moisture, direct sunlight, and high temperatures. Keep container tightly sealed after opening.