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API Mesaconic acid

Name: API Mesaconic acid
Brand: Hyper Chem
SKU: pr2505071200
Price: 1860 USD
Availability: InStock

2 Inquiries

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CAS No.:

498-24-8

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

Hyper Chem

Packaging:

20kg/Drum 25kg/Drum

Price valid (until):

2025-06-07

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Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

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Product Description
Seller Information
Inquiry History

Description

Name	Mesaconic acid
CAS number	498-24-8
Description	Mesaconic acid is one of several isomeric carboxylic acids obtained from citric acid. It is a colorless solid. It is prepared from citric acid, which is first converted to itaconic anhydride by dehydration and decarboxylation. Itaconic acid anhydride is isomerized to citraconic anhydride, which is hydrolyzed and the resulting acid further isomerized under acid-catalysis to give mesaconic acid. Hydration of mesaconic acid, a conversion catalyzed by mesaconyl-C4-CoA hydratase, gives citramalic acid.
Molecular Formula	C₅H₆O₄
Molecular Weight	130.10
Appearance	Solid powder
Quality Standard	USP, EP, BP, CP
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Dry, dark and at 0 – 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag
Commercial package	Aluminium Tin, Fiber drum
Origin	China

Mesaconic acid More Info

Physical Properties

Melting Point: The melting point of mesaconic acid is around 165 - 169 °C.

Solubility: It is soluble in water, ethanol, and some other polar solvents. Its solubility in water is due to the presence of polar carboxyl groups that can form hydrogen bonds with water molecules.

Chemical Properties

Acidity: Due to the two carboxyl groups, mesaconic acid is a dibasic acid. It can donate two protons in aqueous solution, showing acidic properties. It can react with bases to form salts and esters.

Reactivity of the Double Bond: The double bond in mesaconic acid can undergo addition reactions. For example, it can react with hydrogen halides, halogens, and water. It can also participate in polymerization reactions under appropriate conditions, forming polymers with various properties.

Occurrence and Preparation

Occurrence: Mesaconic acid is not very common in nature. It can be found in some plants and microorganisms, but in relatively small amounts.

Preparation: It can be synthesized through various chemical methods. One common method is the dehydration of citric acid. Another way is the oxidation of some unsaturated hydrocarbons with appropriate oxidizing agents.

Applications

In the Polymer Industry: It is used as a monomer in the production of some polymers. The introduced carboxyl groups can improve the hydrophilicity and reactivity of the polymer, endowing the polymer with better properties such as water - solubility, film - forming ability, and adhesion.

In the Pharmaceutical Industry: It can be used as a raw material or intermediate for the synthesis of some drugs. Its carboxyl and double - bond structures provide reactive sites for the introduction of other functional groups, helping to construct the molecular skeleton of drugs.

In the Field of Organic Synthesis: It serves as an important intermediate in organic synthesis reactions. It can participate in various reactions to synthesize a variety of organic compounds with different structures and functions, providing a basis for the synthesis of complex organic molecules.

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Basic Info

Product Name:

Mesaconic acid

Other Name:

2-Butenedioic acid,2-methyl-,(2E)-;Mesaconic acid;2-Butenedioic acid,2-methyl-,(E)-;(2E)-2-Methyl-2-butenedioic acid;trans-2-Methyl-2-butenedioic acid;Methylfumaric acid;trans-1-Propene-1,2-dicarboxylic acid;2-Methylfumaric acid;Citronic acid;(E)-Citraconic acid;NSC 65438

CAS No.:

498-24-8

Molecular Formula:

C5H6O4

InChIKeys:

InChIKey=HNEGQIOMVPPMNR-NSCUHMNNSA-N

Molecular Weight:

130.1

Exact Mass:

130.10

EC Number:

207-859-2

UNII:

90UTM639KK

NSC Number:

65438|32949

HScode:

2917190090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

74.60000

XLogP3:

0.10190

Appearance:

Solid

Density:

1.387 g/cm3

Melting Point:

204.5 °C

Boiling Point:

bp 250° (decompn)

Flash Point:

171.5ºC

Refractive Index:

1.514

Water Solubility:

26.3g/L(18 ºC)

Storage Conditions:

2-8°C

See More Mesaconic acid Properties 

Hazard Identification

Classification of the substance or mixture

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity â single exposure, Category 3

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area.
Response	P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P319 Get medical help if you feel unwell.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Mesaconic acid Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Certifications:
Certification Report by Bureau Veritas

About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

2 Inquiries

Country	Product	Purchase Quantity	Date Posted
Germany	4-Butendiol	2500 G	Jul 31, 2024
New Zealand	Mesaconic acid	5 KG	May 6, 2025

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