Upadacitinib is used to treat certain types of arthritis (such as psoriatic arthritis, rheumatoid arthritis, ankylosing spondylitis
Application
Upadacitinib is an oral Janus kinase (JAK) 1-selective inhibitor and an anti-rheumatic drug that improves the condition. Upadacitinib is used to treat rheumatoid arthritis to slow down the progression of the disease. Rheumatoid arthritis is a chronic autoimmune inflammatory disease that affects peripheral joints. Its characteristics include synovial inflammation and hyperplasia, production of autoantibodies, cartilage damage and bone destruction, leading to complications. (Chemicalbook)
Biological activity
The chemical nature of the hydrate form of upadacitinib is upadacitinib. Upadacitinib is an oral Janus kinase subtype 1 (JAK1) selective inhibitor. JAKChemicalbook belongs to the cytoplasmic tyrosine kinase family. Its function is to conduct the signal mediated by cytokines (such as interferons). There are four JAK subtypes, and there are overlapping binding sites among them.
| Items | Specifications |
| CAS No. | 2050057-56-0 |
| MF | C17H21F3N6O2
|
| MW | 398.39 |
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