Top Grade CAS 3604-87-3 Ecdysone Powder Bulk Ecdysone Cyanotis Extract Ecdysone

I. Overview

• Chemical Properties and Sources:
  Ecdysone is a naturally occurring steroid hormone with the molecular formula C₂₇H₄₄O₇, a molecular weight of 480.63, and a CAS registry number of 5289-74-7. It is widely found in insects, arthropods, and certain plants. As a key hormone regulating insect molting and metamorphosis, its active metabolite, 20-hydroxyecdysone (20E), plays a critical role in biological processes.

• Physiological Functions:
  Ecdysone exerts its effects by binding to the ecdysone receptor (EcR), thereby modulating insect molting, metamorphosis, programmed cell death, and tissue remodeling. Additionally, it participates in the regulation of homeostasis and sleep patterns.

II. Applications

1. Agriculture and Aquaculture
   • Insect Growth Regulation: Ecdysone analogs, functioning as insect growth regulators (IGRs), disrupt normal insect development, leading to premature molting or malformations, thereby controlling pest populations.
   • Aquaculture: Used to promote molting in crustaceans such as shrimp and crabs, enhancing survival rates and improving commercial size.
   • 
     
2. Pharmaceuticals and Health Supplements
   • Anti-inflammatory and Immunomodulatory Effects: Studies indicate that ecdysone can suppress the expression of inflammatory factors (e.g., NF-κB, TNF-α), thereby alleviating inflammatory damage.
   • Antitumor Activity: It exhibits growth-inhibitory effects on various cancer cell lines, potentially through mechanisms such as apoptosis induction and DNA synthesis inhibition.
   • Hypoglycemic and Antidiabetic Effects: Clinical research has shown that ecdysone can reduce blood glucose levels in patients with type II diabetes and alleviate associated symptoms (e.g., polyuria, polydipsia, polyphagia, and weight loss).
   • Sports Nutrition: By promoting protein synthesis, ecdysone enhances muscle growth and repair, offering high safety and minimal side effects.
   • 
     
3. Cosmetics and Skincare
   • Anti-aging and Repair: High-purity ecdysone can boost cellular metabolism, stimulate collagen synthesis, improve skin elasticity, and reduce wrinkles and pigmentation.
   • Exfoliation and Whitening: It possesses effective exfoliating and whitening properties, aiding in the repair of facial melasma, freckles, and other skin conditions.
   • 
     
4. Scientific Research
   • Developmental Biology Studies: As a vital tool in model organism research, ecdysone is employed to elucidate the molecular mechanisms underlying insect development and metamorphosis.
   • Drug Development: Its active metabolite, 20-hydroxyecdysone, holds potential applications in pharmaceutical research and development.