Factory Supply Best Quality Biotinoyl Tripeptide-1

I. Overview

• Basic Information:
  Biotinoyl Tripeptide-1 is a compound that combines vitamin H (biotin) with a Matrikine-derived signaling tripeptide, GHK. Its chemical formula is C₂₄H₃₈N₈O₆S, with a molecular weight of 566.67 g/mol and a CAS number of 299157-54-3. It typically appears as a white powder or liquid, with a purity exceeding 98%.

• Structure and Composition:
  Biotinoyl Tripeptide-1 is formed by conjugating biotin with the tripeptide GHK (glycyl-L-histidyl-L-lysine). This structure endows it with both the nutritional properties of biotin and the signaling functions of GHK, enabling it to exert multiple effects in biological systems.

• Physiological Functions:
  Biotinoyl Tripeptide-1 stimulates the synthesis of collagen IV and laminin-5, thereby enhancing hair follicle adhesion and metabolic activity. This helps delay hair follicle aging and improve follicular structure. Additionally, it activates the expression of tissue repair genes, promoting the reconstruction and repair of skin structures.

II. Applications

1. Cosmetics Industry:
   • Hair Loss Prevention and Hair Growth Promotion:
     In cosmetics, Biotinoyl Tripeptide-1 is primarily used for hair loss prevention and promoting hair growth. It strengthens hair follicle resistance, protects against environmental damage, and prolongs the hair growth cycle. Multiple studies have demonstrated that products containing this ingredient can significantly reduce hair loss and promote the growth of hair and eyelashes. For instance, in a study on eyelash growth, a mascara containing 2% Biotinoyl Tripeptide-1 increased eyelash length by 17% and thickness by 19% after 30 days of use.
   • Scalp Environment Improvement:
     This ingredient also improves scalp blood circulation, providing adequate nutrition and oxygen to hair follicles, thereby reducing dandruff production and maintaining a healthy scalp.
   • Product Forms:
     Biotinoyl Tripeptide-1 is commonly incorporated into mascaras, eyelash care serums, hair growth solutions, and other hair care products. Its efficacy is comparable to 2PPM minoxidil, but it is milder in nature and suitable for long-term use.
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2. Pharmaceutical and Scientific Research Fields:
   • Hair Follicle Repair and Regeneration:
     In the pharmaceutical field, Biotinoyl Tripeptide-1 is being studied for its potential in repairing and regenerating damaged hair follicles. By promoting extracellular matrix synthesis and activating tissue repair gene expression, it provides a favorable microenvironment for hair follicles, facilitating hair regeneration.
   • Skin Repair:
     This ingredient also promotes the proliferation and differentiation of skin cells, accelerating the repair process of skin injuries. Therefore, in scientific research, it is used to study the mechanisms of skin aging and injury repair.