PFA resin Translucent particles or white powder
4428-95-9
Chemical Grade
99%
shanghai
FLON MAKE
25kg/carton
Yes
2026-12-31
FPA,PTFE,PVDF,ECTFE,PES,FEP
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceChEBI: Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to bl ndness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.
Solid
Phosphonoformic acid is phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity. It has a role as an antiviral drug, a sodium-dependent Pi-transporter inhibitor, a HIV-1 reverse transcriptase inhibitor and a geroprotector. It is a one-carbon compound, a member of phosphonic acids and a carboxylic acid. It derives from a phosphonic acid and a formic acid. It is a conjugate acid of a phosphonatoformate and a phosphonoformate(2-).|An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.|Foscarnet is a Pyrophosphate Analog DNA Polymerase Inhibitor. The mechanism of action of foscarnet is as a DNA Polymerase Inhibitor, and Chelating Activity.|Foscarnet a simple pyrophosphate molecule which has antiviral activity against many viruses and is used intravenously in therapy of serious cytomegalovirus infections, largely in immunocompromised patients. Foscarnet has been associated with mild-to-moderate serum aminotransferase elevations during intravenous therapy, but not with episodes of clinically apparent liver injury.|Foscarnet is a synthetic organic analog of inorganic pyrophosphate with activity against several types of viruses, but primarily used for the treatment of cytomegalovirus retinitis. Foscarnet selectively blocks the pyrophosphate binding site of virus-specific DNA polymerases at concentrations that do not affect cellular DNA polymerases. Because this agent crosses the blood brain barrier, it may be used in the treatment of viral infections of the central nervous system.|An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.Basic Info-
Product Name:
Foscarnet
Other Name:Phosphinecarboxylic acid,1,1-dihydroxy-,1-oxide;Formic acid,phosphono-;Phosphinecarboxylic acid,dihydroxy-,oxide;Phosphonic acid,carboxy-;Phosphonoformic acid;Foscarnet;Carboxyphosphonic acid;Phosphonocarboxylic acid;PFA
CAS No.:4428-95-9
Molecular Formula:CH3O5P
InChIKeys:InChIKey=ZJAOAACCNHFJAH-UHFFFAOYSA-N
Molecular Weight:126.004
Exact Mass:126.01
UNII:364P9RVW4X
DSSTox ID:DTXSID0048478
NCI Thesaurus Code:C71630
ATC Code:J05AD01|J - Antiinfectives for systemic use
Categories:
Characteristics-
PSA:
94.8
XLogP3:-2.1
Appearance:Solid
Melting Point:88.06 °C
Water Solubility:Completely soluble in water.
Storage Conditions:Store at 20 to 25 deg C (68 to 77 deg F). Protect from excessive heat (above 40 deg C) and from freezing.
Vapor Pressure:1.62X10-6 mm Hg at 25 deg C (est)
Henrys Law Constant:Henry's Law constant = 2.01X10-15 atm-cu m/mol at 25 °C (est)
Dissociation Constants:pKa = 3.13 (est)
Experimental Properties:Hexahydrate, mp >250 °C/Foscarnet sodium/|Hydroxyl radical reaction rate constant = 8.0X10-13 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
FPA,PTFE,PVDF,ECTFE,PES,FEP
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Location:
Jinyi Expressway,Tangya Town,Jindong District,Jinhua,Zhejiang Province
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
15 days
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Total Annual Revenue:
$1 million-$2.5 million
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Total Employees:
11-50
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Year of Establishment:
2021
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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