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RG 108

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CAS No.:

48208-26-0

Port:

shanghai

Packaging:

500mg/bottle

Price valid (until):

2025-07-30

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Shandong zhishang chemical Co.,Ltd

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Dichloromethane,Linocaine hydrochloride

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Product Description
Seller Information
Inquiry History

Description

Product Detail

RG108effectivelyblocksDNAmethyltransferasesinvitroanddoesnotcausecovalentenzymetrappinginhumancelllines.IncubationofcellswithlowmicromolarconcentrationsofRG108resultsinsignificantdemethylationofgenomicDNAwithoutanydetectabletoxicity.Intriguingly,RG108causesdemethylationandreactivationoftumorsuppressorgenes,butitdoesnotafChemicalbookfectthemethylationofcentromericsatellitesequences.Inanotherstudy,thesynthesisandinvitroanalysisofabiotinylatedRG108conjugateisinvestigatedtoevaluatetheinteractionswithDNAmethyltransferaseenzymes.Inarecentstudy,itisshownRG108cansignificantlyreducetheDNAmethyltransferasesactivityinSMderivediPScellsascomparedtothenativeSMs.

Items	Specifications

Basic Info

Product Name:

RG108

Other Name:

RG108/RG-108;(S)-3-(Indol-3-yl)-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)propanoic acid;N-Phthaloyl-L-tryptophan;(S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid;1H-Indole-3-propanoic acid, α-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-, (αS)-;N-Phthaloyl-L-tryptophan(S)-3-(Indol-3-yl)-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)propanoic acid;DNA Methyltransferase Inhibitor;N-Phthalyl-L-tryptophan

CAS No.:

48208-26-0

Molecular Formula:

C19H14N2O4

InChIKeys:

HPTXLHAHLXOAKV-INIZCTEOSA-N

Molecular Weight:

334.33

Exact Mass:

334.095367

Categories:

Organic Reagents

Characteristics

PSA:

90.5

XLogP3:

2.6

Appearance:

yellow

Density:

1.5±0.1 g/cm3

Melting Point:

192-194℃

Boiling Point:

670.3°C at 760 mmHg

Flash Point:

320.3±30.1 °C

Refractive Index:

1.741

Water Solubility:

DMSO: >10mg/mL

Storage Conditions:

Store at RT

See More RG108 Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More RG108 Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Dichloromethane,Linocaine hydrochloride

Location:
BUILDING 1,HISENSE INTELLIGENCE VALLEY,NO.2116,OF PHOEIX ROAD, HIGH-TECH ZONE ,JINAN CITY ,SHANDONG PROVINCE,CHINA

Payment Terms:
D/P,L/C,D/A

Average lead Time:
15

Total Annual Revenue:
$10 million-$25 million

Total Employees:
11-50

Year of Establishment:
2016

Shandong zhishang chemical Co.,Ltd is a leading Manufactory supplier of Adenosine, 5′-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5′-deoxy-, sulfate, 4-methylbenzenesulfonate sulfate (1:1:1:1), Ethylene oxide-propylene oxide copolymer, Strontium carbonate based in Jinan, Shandong, China. With a commitment to quality and customer satisfaction, Shandong zhishang chemical Co.,Ltd has become a trusted name in the industry. Our product line includes a range of high-quality Adenosine, 5′-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5′-deoxy-, sulfate, 4-methylbenzenesulfonate sulfate (1:1:1:1), Ethylene oxide-propylene oxide copolymer, Strontium carbonate, which are available at competitive prices. Shandong zhishang chemical Co.,Ltd has established itself as a reliable supplier of chemical products on the echemi.com.

Inquiry History

2 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	RG108	500 MG	Jun 29, 2025
Germany	RG108	2 G	Mar 23, 2026

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