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Semaglutide, CAS Number: 910463-68-2, peptide raw material, HPLC purity not less than 98 percent, bulk supply available for pharmaceutical manufacture buy - large image1

Semaglutide, CAS Number: 910463-68-2, peptide raw material, HPLC purity not less than 98 percent, bulk supply available for pharmaceutical manufacture

Name: Semaglutide, CAS Number: 910463-68-2, peptide raw material, HPLC purity not less than 98 percent, bulk supply available for pharmaceutical manufacture
Brand: HyperChem
SKU: pr2507111018
Price: 200 USD
Availability: InStock

TDS 27 Inquiries

Unit Price:

$200-220/G FOB

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CAS No.:

144060-53-7

Grade:

Pharmaceutical Grade

Content:

99%

Port:

SHANGHAI

Brand:

HyperChem

Packaging:

g,Kg

Price valid (until):

2026-09-23

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Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

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Product Description
Seller Information
Inquiry History

Description

Name	Sermaglutide
CAS number	910463-68-2
Description	Semaglutide was originally designed as a powerful, long-lasting subcutaneous anti-diabetic drug. In 2019, oral semaglutide tablets were also approved for marketing, reducing the trauma of medication for diabetic patients and improving medication compliance and convenience.
Molecular Formula	C187H291N45O59
Molecular Weight	4113.57 g/mol
Appearance	White powder
Quality Standard	99%
Storage Condition	Store at -20°C.
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag
Commercial package	Aluminium Tin, Fiber drum
Origin	China

Semaglutide Blue Trihydrate More Info

Semaglutide is a GLP-1 receptor agonist developed by Novo Nordisk, engineered for extended half-life to enable once-weekly subcutaneous administration. It is approved for type 2 diabetes management and chronic weight management. The compound mimics endogenous GLP-1 to enhance glucose-dependent insulin secretion, suppress glucagon, and delay gastric emptying.

Production and Pharmaceutical Development

Semaglutide is synthesized via recombinant DNA technology, using yeast or mammalian cell systems, followed by chemical modification (e.g., fatty acid side chain) to prolong activity. Critical steps include peptide synthesis (SPPS or fermentation), purification, and formulation. Its design ensures stable pharmacokinetics, reducing dosing frequency compared to shorter-acting analogs.

Clinical Applications and Efficacy

Clinical trials demonstrate semaglutide’s ability to significantly reduce HbA1c (diabetes) and body weight . It also shows cardiovascular benefits, lowering MACE risk in high-risk patients. The weekly dosing regimen improves adherence versus daily GLP-1 therapies.

Safety and Regulatory Considerations

Semaglutide requires risk mitigation for potential adverse effects (e.g., gastrointestinal reactions, thyroid C-cell tumor risk in rodents). Patients with a history of medullary thyroid carcinoma or multiple endocrine neoplasia are contraindicated. Ongoing studies explore broader applications (e.g., NASH), while post-marketing surveillance monitors long-term safety.

FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

T/T in advance
LC at sight
DP at sight

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Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express
FedEx UPS DHL EMS
Fast: 3-7 days around, high cost, door to door service

By Air
Suitable for more than 50kg
Fast: 3-7 days, hight cost, port to port, professional broker needed

By Sea
Suitable for more than 500kg
Fast: 7-45 days, low cost, port to port, professional broker needed

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders:
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.

ECHEMI Editorial Reference

Crystalline SolidFebuxostat, a selective xanthine oxidase inhibitor, was launched for the chronic management of hyperuricemia in patients with gout. Hyperuricemia is defined as a serum uric acid concentration exceeding the limit of solubility. It predisposes affected persons to gout, a disease characterized by the formation of crystals of monosodium urate or uric acid from supersaturated fluids in joints and other tissues. Crystal deposition is asymptomatic, but it is revealed by bouts of
Febuxostat is a 1,3-thiazolemonocarboxylic acid that is 4-methyl-1,3-thiazole-5-carboxylic acid which is substituted by a 3-cyano-4-(2-methylpropoxy)phenyl group at position 2. It is an orally-active, potent, and selective xanthine oxidase inhibitor used for the treatment of chronic hyperuricaemia in patients with gout. It has a role as an EC 1.17.3.2 (xanthine oxidase) inhibitor. It is an aromatic ether, a nitrile and a 1,3-thiazolemonocarboxylic acid.|Febuxostat is a xanathine oxidase (XO) inhibitor indicated in patients with gout suffering from hyperuricemia and is used in its chronic management. Febuxostat is not recommended for the treatment of asymptomatic hyperuricemia. Febuxostat is marketed under the trade name Uloric by Takeda Pharmaceuticals America, Inc., and was approved by the FDA in February 2009.|Febuxostat is a Xanthine Oxidase Inhibitor. The mechanism of action of febuxostat is as a Xanthine Oxidase Inhibitor.|Febuxostat is a newly introduced nonpurine xanthine oxidase inhibitor used for the treatment of gout. Chronic febuxostat therapy has been associated with minor serum aminotransferase elevations, but has yet to be linked to cases of clinically apparent acute liver injury.|Febuxostat is an orally available, non-purine inhibitor of xanthine oxidase with uric acid lowering activity. Upon oral administration, febuxostat selectively and noncompetitively inhibits the activity of xanthine oxidase, an enzyme that converts oxypurines, including hypoxanthine and xanthine, into uric acid. By inhibiting xanthine oxidase, uric acid production is reduced and serum uric acid levels are lowered. Febuxostat may provide protection against acute renal failure caused by the excessive release of uric acid that occurs upon massive tumor cell lysis resulting from the treatment of some malignancies.|A thiazole derivative and inhibitor of XANTHINE OXIDASE that is used for the treatment of HYPERURICEMIA in patients with chronic GOUT.

Certificates

Basic Info

Product Name:

Febuxostat

Other Name:

5-Thiazolecarboxylic acid,2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-;2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid;TEI 6720;TMX 67;2-(3-Cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid;Febuxostat;FBX;Uloric;Feburic;Febugood;Febutaz;Zurig;2-(3-Cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid;2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid;Adenuric

CAS No.:

144060-53-7

Molecular Formula:

C16H16N2O3S

InChIKeys:

InChIKey=BQSJTQLCZDPROO-UHFFFAOYSA-N

Molecular Weight:

316.37500

Exact Mass:

316.37

UNII:

101V0R1N2E

NSC Number:

758874

DSSTox ID:

DTXSID8048650

NCI Thesaurus Code:

C65629

ATC Code:

M04AA03|M - Musculo-skeletal system

HScode:

2934100090

Categories:

Antibiotics

Characteristics

PSA:

111.45000

XLogP3:

3.9

Appearance:

Crystalline Solid

Density:

1.31 g/cm3

Melting Point:

238-239ºC

Boiling Point:

536.6ºC at 760 mmHg

Flash Point:

278.3ºC

Refractive Index:

1.605

Vapor Pressure:

2.41E-12mmHg at 25°C

Collision Cross Section:

180.6 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Research

Class:

GLP-1R agonist

Status:

FDA-approved (Ozempic / Wegovy / Rybelsus)

Mechanism:

Long-acting, selective glucagon-like peptide-1 (GLP-1) receptor agonist with 94% sequence homology to human GLP-1. Engineered for extended half-life (~1 week) via albumin binding (fatty acid acylation at Lys26) and resistance to DPP-4 degradation (Aib substitution at position 8). Promotes insulin secretion, inhibits glucagon release, delays gastric emptying, and reduces appetite via central nervous system GLP-1R activation.

Activity note:

Potent, selective GLP-1R agonist. Reported binding affinity Ki = 0.38 ± 0.06 nM. Semaglutide is a human GLP-1 analog with structural modifications for albumin binding (C18 fatty diacid at Lys26) and enzymatic stability (Aib8 substitution).

Source:

Lau J, et al. J Med Chem. 2015;58(18):7370-7380. Wilding JPH, et al. N Engl J Med. 2021;384(11):989-1002.DOI

Clinical Development:

NCT03548935; NCT03552757; NCT01720446; NCT02692716

FDA:

Ozempic, Wegovy, Rybelsus (approved 2017-12-05)

References

ChEMBL:

DrugBank:

KEGG DRUG:

PubChem:

Literature:

NEJM: Wilding et al. (2021) — STEP-1; NEJM: Marso et al. (2016) — SUSTAIN-6; J Med Chem: Lau et al. (2015) — Discovery of Semaglutide; FDA: Ozempic (NDA 209637)

Disclaimer:

Semaglutide is approved as a prescription medicine (Ozempic, Wegovy, Rybelsus) in certain jurisdictions. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.

See More Febuxostat Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Febuxostat Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Certifications:
Certification Report by Bureau Veritas

About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

27 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Febuxostat	1.00 KG	Jan 19, 2024
India	Febuxostat	5.00 KG	Jan 22, 2024
Pakistan	Febuxostat	800.00 KG	Aug 4, 2026
India	FEBUXOSTAT USP	40.00 KG	Oct 16, 2025
Philippines	Febuxostat	1 KG	Jun 2, 2026
India	Febuxostat	1.00 KG	May 9, 2026
India	Febuxostat	1.00 KG	Apr 21, 2026
India	Febuxostat	2 MT	May 17, 2024
India	Febuxostat	1.00 MT	Jun 16, 2026
India	Febuxostat	1.00 KG	Jun 4, 2026
India	Febuxostat	1.00 KG	May 27, 2026
India	Febuxostat	100.00 KG	Apr 23, 2026
Pakistan	Febuxostat	300.00 KG	Feb 24, 2026
Pakistan	Febuxostat	50 KG	Jan 12, 2026
India	FEBUXOSTAT	25.00 KG	Mar 25, 2025
India	Febuxostat	1.00 KG	Mar 15, 2024
India	Febuxostat	200.00 KG	Jun 22, 2026
Pakistan	Febuxostat	300.00 KG	Apr 20, 2026
Pakistan	Febuxostat	300.00 KG	Mar 16, 2026
India	Febuxostat	500.00 KG	Nov 28, 2025

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