 Home > Active Pharmaceutical Ingredients > Other Chemical Drugs > 5,6-Dihydro-3-(4-morpholinyl)-1-[4-(2-... for Sale > 3-Morpholino-1- (4-(2-oxopiperidin-1-yl)phenyl) -5, 6-Dihydropyridin-2 (1H) -One Apixaban Intermediate CAS 545445-44-1

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3-Morpholino-1- (4-(2-oxopiperidin-1-yl)phenyl) -5, 6-Dihydropyridin-2 (1H) -One Apixaban Intermediate CAS 545445-44-1 buy - image1

3-Morpholino-1- (4-(2-oxopiperidin-1-yl)phenyl) -5, 6-Dihydropyridin-2 (1H) -One Apixaban Intermediate CAS 545445-44-1 buy - image2

3-Morpholino-1- (4-(2-oxopiperidin-1-yl)phenyl) -5, 6-Dihydropyridin-2 (1H) -One Apixaban Intermediate CAS 545445-44-1 buy - image3

3-Morpholino-1- (4-(2-oxopiperidin-1-yl)phenyl) -5, 6-Dihydropyridin-2 (1H) -One Apixaban Intermediate CAS 545445-44-1 buy - image4

3-Morpholino-1- (4-(2-oxopiperidin-1-yl)phenyl) -5, 6-Dihydropyridin-2 (1H) -One Apixaban Intermediate CAS 545445-44-1

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CAS No.:

545445-44-1

Grade:

Pharmaceutical Grade

Content:

99%

Port:

qingdao

Brand:

Packaging:

25kg/drum

Price valid (until):

2026-01-31

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NATURE INDUSTRIAL LIMITED

Company Type:

Trader

Location:

Hongkong, China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

7 days

Qualification:

Main Products:

Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

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Product Details
Seller Information

Description

3-Morpholino-1- (4-(2-oxopiperidin-1-yl)phenyl) -5, 6-Dihydropyridin-2 (1H) -One Apixaban Intermediate CAS 545445-44-1

Apixaban is an anticoagulant used to reduce the risk of stroke and systemic embolism in patients with non valvular atrial fibrillation.
A key component in helping our customers be first to market is a responsive supply chain. We achieve this by making sure that all our facilities are operating efficiently and to the latest standards of quality, safety, and productivity. A strong interconnect between business and factories allows for a quick reaction to dynamic market changes, so that we can avert shortages and meet sudden surges in demand.
Apixaban is a selective inhibitor of FXa. It does not require antithrombin III for antithrombotic activity. Apixaban inhibits free and clot-bound FXa, and prothrombinase activity. Apixaban has no direct effect on platelet aggregation, but indirectly inhibits platelet aggregation induced by thrombin. By inhibiting FXa, apixaban decreases thrombin generation and thrombus development

Product Description

3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one Apixaban Intermediate CAS 545445-44-1

1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester	503614-91-3	Apixaban intermediate
Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester	27143-07-3	Apixaban intermediate
2(1H)-pyridine,3-chloro-5,6-dihydro-1-(4-nitrophenyl)	536760-29-9	Apixaban intermediate
3-Morpholin-4-yl-1-[4-(2-oxopiperidin-1-yl)phenyl]-5,6-dihydro-1H-pyridin-2-one	545445-44-1	Apixaban intermediate
3-(4-Morpholinyl)-1-(4-nitrophenyl)-5,6-dihydro-2(1H)-pyridinone	503615-03-0	Apixaban intermediate
Ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3	536759-91-8	Apixaban intermediate
ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate	503615-07-4	Apixaban intermediate
1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone	1267610-26-3	Apixaban intermediate

◼ Superior Efficacy
▸ 21% risk reduction in stroke vs. warfarin (ARISTOTLE trial)
▸ 50% lower major bleeding rates in orthopedic surgeries

◼ Logistics Advantage
▸ Temperature-stable formulation (25°C/77°F ambient storage)
▸ Multilingual packaging compliant with international GMP

◼ Regulatory Excellence
▸ WHO Essential Medicines List (2019) inclusion
▸ Recipient of 7 international pharmaceutical innovation awards

"From Munich to Melbourne, Apixaban protects 2.3 million patients annually" - 2024 Global Anticoagulation Report

Available in:
• 2.5mg & 5mg film-coated tablets
• Hospital/clinic bulk procurement programs
• Customized blister pack configurations

Export Documentation Ready:
• Certificate of Pharmaceutical Product (CPP)
• WHO-GMP compliance statements
• Full dossier support for new market registration

We also supply Apixaban intermediates, 503614-91-3 545445-44-1 welcome to send enquiry.

Basic Info

Product Name:

5,6-Dihydro-3-(4-morpholinyl)-1-[4-(2-...

CAS No.:

545445-44-1

Molecular Formula:

C20H25N3O3

InChIKeys:

SCVWQFDPLBFZAP-UHFFFAOYSA-N

Molecular Weight:

355.43

Exact Mass:

355.189606

DSSTox ID:

DTXSID60625157

HScode:

2934999090

Categories:

Other Chemical Drugs

Characteristics

PSA:

53.1

XLogP3:

1.6

Density:

1.3±0.1 g/cm3

Boiling Point:

624.979°C at 760 mmHg

Flash Point:

331.8±31.5 °C

Refractive Index:

1.611

See More 5,6-Dihydro-3-(4-morpholinyl)-1-[4-(2-... Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 5,6-Dihydro-3-(4-morpholinyl)-1-[4-(2-... Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

Location:
Unit D01,3/F., Wong King Industrial Building,No.2 Tai Yau Street, Kowloon

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7 days

Total Annual Revenue:
$50 million-$100 million

Total Employees:
51-100

Year of Establishment:
2012

We have more than 10 years experience in the pharmacy filed. Mainly manufactures pharmaceutical APIs,Pharmaceutical intermediate and Cosmetic raw material. Owing to the good quality and competitive price, we have a very good reputation in China's pharmaceutical circles.

In the principle of "Quality Oriented", Jianfeng passed the certification of ISO9001:2008 Quality Management System.

Our products are based on bulk, high volume, wholesale price, third party testing, certificate reporting, and bring high quality ingredients to many domestic and overseas enterprises.

"Honesty, practicality, innovation, development" are our values. Jianfeng would like to cooperate with you with high quality products and competitive price.
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3-Morpholino-1- (4-(2-oxopiperidin-1-yl)phenyl) -5, 6-Dihydropyridin-2 (1H) -One Apixaban Intermediate CAS 545445-44-1

Product Details

Seller Information

Product Description

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

More Choices Find All Products for Sale 

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