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Home > Active Pharmaceutical Ingredients > Antineoplastic Agents > Docetaxel for Sale > 99% Assay Docetaxel CAS114977-28-5 EP Standard White Powder Taxotere
99% Assay Docetaxel CAS114977-28-5 EP Standard White Powder Taxotere buy - large image1
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99% Assay Docetaxel CAS114977-28-5 EP Standard White Powder Taxotere

TDS 3 Inquiries

Unit Price: Get Latest Price
CAS No.:

114977-28-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

HyperChem

Packaging:

1kg/Bag, 25kg/drum

Price valid (until):

2025-09-09

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Name

    Docetaxel

    CAS number

    114977-28-5

    EINECS number

    601-339-2

    Synonym

    benz(1,2-b)oxet-9-ylester,(2ar-(2a-alpha,4-beta,4a-beta,6-beta,9-alpha(alph;Benzenepropanoicacid,b-[[(1,1-dimethylethoxy)carbonyl]amino]-a-hydroxy-,(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-ylester,(aR,bS)-

    Description

    Docetaxel is a semi synthetic derivative of paclitaxel, which is extracted from the European yew tree as a monomer 10 deacetylated berry gibberellin and is a hydrophilic anti-tumor drug. Similar to the mechanism of action of paclitaxel, it binds to microtubule proteins, promotes microtubule stability, and leads to G2/M cell cycle arrest.

    Structure

    Shop 99% Assay Docetaxel CAS114977-28-5 EP Standard White Powder Taxotere-Detailed Image 1

    Molecular Formula

    C43H53NO14

    Molecular Weight

    807.88g/mol

    Appearance

    White Crystalline Powder

    Quality Standard

    EP

    Assay

    99.88%

    Sample package

    Aluminium foil bag

    Commercial package

    Aluminium Tin, Fiber drum

    Origin

    China


    More Info

    Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of paclitaxel.

    Applications

    Antineoplastic drugs for the treatment of metastatic breast cancer and non-small cell lung cancer. 


    Mechanism of action

    Docetaxel is a paclitaxel class drug that promotes the assembly of microtubule dimers into microtubules, while stabilizing microtubules by preventing depolymerization, blocking cells in the G2 and M phases, thereby inhibiting cancer cell mitosis and proliferation. Docetaxel has stronger pharmacological effects than paclitaxel, with a concentration three times higher in cells and a longer retention time. Its affinity for microtubules is twice that of paclitaxel; As a microtubule stabilizer and assembly promoter, its activity is twice that of paclitaxel; As a microtubule depolymerization inhibitor, its activity is twice that of paclitaxel. In vitro anti-tumor activity tests have confirmed that the anti-tumor activity of docetaxel is 1.3-12 times that of paclitaxel.








    Package Image

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    FAQ

    Q1. Can I get a free sample?

    We can send you a samll free sample, and you only need to pay for the shipping cost.


    Q2. What is the HyperChem payment term?

    T/T in advance
    LC at sight
    DP at sight

    Bank transfer

    PayPal

    Bitcoin...


    Q3. What is HyperChem shipment policy?

    Our policy is to strive for the quickest shipment time possible.

    For ready stock samples, they are usually shipped within 3 working days after payment received.
    For non-ready stock, please contact HyperChem sales team to negotiate.


    Q4. What is HyperChem shipment term?

    By Express  
    FedEx  UPS  DHL  EMS                               
    Fast: 3-7 days around, high cost, door to door service

    By Air                                        
    Suitable for more than 50kg 
    Fast: 3-7 days, hight cost, port to port, professional broker needed 

    By Sea
    Suitable for more than 500kg      
    Fast: 7-45 days, low cost, port to port, professional broker needed 


    We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.


    Q5. What HyperChem will provide after shipment?

    For sample orders: 
    After shipment is done, an timely email including:

    1. Track details (Fedex /TNT/DHL/EMS Track number)
    2. Packaging photo
    3. COA, MSDS, etc
    4. Dispatch date & Estimated arriving time
    5. Shipping invoice

    For commercial orders
    A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.



    Company Profile

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.


    Among them, our key client industrial sectors around the global are:

    Pharmaceuticals
    Nutrition Ingredients/ Dietary supplements
    Cosmetic Ingredients
    Food Ingredients
    Veterinary API
    Agriculture fertilizer
    Custom Synthesis lab supply


    HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.




    Certificates

    Basic Info
    Product Name:

    Docetaxel

    Other Name:

    Benzenepropanoic acid,β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-,(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester,(αR,βS)-;Benzenepropanoic acid,β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-,12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester,[2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-;7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete,benzenepropanoic acid deriv.;RP 56976;Docetaxel;Taxotere;N-Debenzoyl-N-tert-butoxycarbonyl-10-deacetyltaxol;Docetaxol;Docetere;Taxotel;SID 530;Duopafei;Docefrez;BIND 014;Miradocetaxel;CKD 810;CRLX 301;ATI 1123;216252-50-5;129522-72-1

    CAS No.:

    114977-28-5

    Molecular Formula:

    C43H53NO14

    InChIKeys:

    InChIKey=ZDZOTLJHXYCWBA-VCVYQWHSSA-N

    Molecular Weight:

    807.87900

    Exact Mass:

    807.88

    EC Number:

    601-339-2

    HScode:

    2932999099

    Categories:

    Antineoplastic Agents

    Characteristics
    PSA:

    224.45000

    XLogP3:

    1.6

    Appearance:

    Off-white Cryst.

    Density:

    1.37 g/cm3

    Melting Point:

    232 °C

    Boiling Point:

    900.5ºC at 760 mmHg

    Flash Point:

    498.4ºC

    Refractive Index:

    1.618

    Water Solubility:

    1.27e-02 g/L

    Storage Conditions:

    Keep tightly closed. Store at +4ºC.

    Vapor Pressure:

    5.61X10-27 mm Hg at 25 deg C (est)

    Hazard Identification

    Classification of the substance or mixture

    Reproductive toxicity, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H361 Suspected of damaging fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

    Location:

    Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2013

    Certifications:

    Certification Report by Bureau Veritas

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

    Our Competitiveness

    One-stop supply

    Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

    Among all the pharmaceuticals,

    90% of them with GMP certificates,

    85% of them with DMF files and

    50% of them passed FDA approval,

    30% get CEP certificate

    20% are new R&D products.

    Custom Repackaging Service


    We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

    Quality Control/Quality Assurance


    HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

    All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

    Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

    Professional

    Transparent Communication

    Fast Reaction,

    Professional Suggestion

    Beyond Expectation.

    We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

  • Inquiry History
    3 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Factory Raw Powder Pharmaceutical Docetaxel CAS 114977-28-5 High Purity 99%

    1 KG Oct 20, 2023
    Nigeria

    Docetaxel

    5 G Apr 13, 2026
    Brazil

    Docetaxel

    1.00 KG Mar 29, 2025
    Post an enquiry for this product
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