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EAST CHEM Panthenol Dexpanthenol

18 Inquiries

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CAS No.:

81-13-0

Content:

99%

Port:

QINGDAO

Packaging:

25KG/DRUM

Price valid (until):

2025-10-01

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QINGDAO EAST CHEMSOURCES TRADE CO.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Food additives,Pharmaceutical raw materials,Chemicals,Comestic raw materials

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Product Description
Seller Information
Inquiry History

Description

Product Detail

1. Product Identification

Item	Details
Chemical Name	(R)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide
Synonyms	Dexpanthenol; D-Panthenol; (R)-Panthenol; Vitamin B5 alcohol
CAS Number	81-13-0
Molecular Formula	C₉H₁₉NO₄
Molecular Weight	205.25 g/mol
Product Grade	Pharmaceutical Grade; Cosmetic Grade; Food Grade

2. Physical and Chemical Properties

Property	Specification
Appearance	Clear, colorless to pale yellow viscous liquid; odorless or slight characteristic odor
Refractive Index	n₂₀/D: 1.495 – 1.502 (ASTM D1218)
Specific Gravity	1.200 – 1.220 g/cm³ at 20°C (ASTM D4052)
Solubility	Miscible with water, ethanol, methanol, and propylene glycol; slightly soluble in ether; insoluble in mineral oil and fats
pH Value	4.5 – 7.0 (5% aqueous solution at 25°C)
Viscosity	400 – 1,200 mPa·s at 25°C (Brookfield LV viscometer)
Stability	Stable under normal storage conditions; sensitive to strong acids/bases (may hydrolyze to pantothenic acid); incompatible with oxidizing agents

3. Quality Specifications (Typical Values)

Parameter	Pharmaceutical Grade	Cosmetic Grade	Food Grade
Assay (Dexpanthenol)	≥ 99.0%	≥ 98.0%	≥ 98.0%
Specific Rotation [α]ᵈ²⁰	+30.0° to +38.0° (10% aqueous solution)	+29.0° to +39.0° (10% aqueous solution)	+29.0° to +39.0° (10% aqueous solution)
Water Content	≤ 0.5%	≤ 1.0%	≤ 1.0%
Residue on Ignition	≤ 0.1%	≤ 0.1%	≤ 0.1%
Heavy Metals (as Pb)	≤ 5 ppm	≤ 10 ppm	≤ 10 ppm
Arsenic (As)	≤ 1 ppm	≤ 2 ppm	≤ 2 ppm
Related Substances	≤ 1.0%	≤ 2.0%	≤ 2.0%
Color (APHA)	≤ 30	≤ 50	≤ 50

4. Applications

Dexpanthenol is the biologically active alcohol form of vitamin B5 (pantothenic acid) and is widely used due to its moisturizing, healing, and nutrient properties:

4.1 Cosmetic & Personal Care Industry

Moisturizers & Creams: Penetrates skin to convert to pantothenic acid, enhancing skin barrier function and reducing transepidermal water loss (TEWL).
Hair Care: Added to shampoos, conditioners, and serums to improve hair elasticity, reduce breakage, and soothe scalp irritation.
Baby Care: Used in lotions, diaper creams, and wipes for its gentle, soothing effect on sensitive skin.
Sunscreens & After-Sun Products: Aids in repairing UV-damaged skin and relieving sunburn discomfort.

4.2 Pharmaceutical Industry

Topical Formulations: Ointments, creams, and sprays for treating minor wounds, burns, dermatitis, and psoriasis (promotes epithelialization).
Oral Supplements: Used to alleviate vitamin B5 deficiency, support wound healing, and reduce fatigue.
Ophthalmic Products: Eye drops for soothing dry eyes and relieving ocular irritation.

4.3 Food & Feed Industry

Food Fortification: Added to energy drinks, cereals, infant formulas, and functional foods as a vitamin B5 source.
Feed Additive: Used in poultry, livestock, and aquaculture feeds to improve growth performance, enhance skin/feather health, and boost immunity.

5. Storage and Handling

5.1 Storage Conditions

Store in a cool, dry, and dark place at temperatures between 15 – 25°C. Avoid exposure to direct sunlight and high temperatures (>40°C).
Keep in tightly sealed original containers to prevent absorption of moisture and contamination.
Do not store near strong acids, bases, or oxidizing agents.

5.2 Shelf Life

36 months from the date of manufacture when stored under recommended conditions (unopened).
Once opened, reseal immediately and use within 6 months.

Basic Info

Product Name:

(+)-Panthenol

Other Name:

Butanamide,2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-,(2R)-;Butyramide,2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-,D-(+)-;Butanamide,2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-,(R)-;(2R)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide;Bepanthen;Bepanthene;Bepantol;Cozyme;Dexpanthenol;D(+)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide;D(+)-α,γ-Dihydroxy-N-(3-hydroxypropyl)-β,β-dimethylbutyramide;Ilopan;D-P-A Injection;Motilyn;Panadon;Panthoderm;Pantol;d-Pantothenol;d-Pantothenyl alcohol;Thenalton;Zentinic;D-Panthenol;Panthenol;Pantothenol;Pantothenyl alcohol;Propanolamine,N-pantoyl-;Panthenol,(+)-;D(+)-Pantothenyl alcohol;D(+)-Panthenol;Synapan;Provitamin B;d-Panthenol;D-Pantothenyl alcohol;Provitamin B5;d-Panthenol 50;Urupan;Alcopan 250;Pantenyl;Intrapan;(+)-Panthenol;NSC 302962;Panthenol 50W;Cornergel;Dolobene;D-Panthenol 75L;Pantogel;(R)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide;(2R)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide;1113-70-8;17307-32-3;50584-68-4

CAS No.:

81-13-0

Molecular Formula:

C9H19NO4

InChIKeys:

InChIKey=SNPLKNRPJHDVJA-ZETCQYMHSA-N

Molecular Weight:

205.251

Exact Mass:

205.25

EC Number:

201-327-3

UNII:

1O6C93RI7Z

DSSTox ID:

DTXSID3022906

NCI Thesaurus Code:

C47481

Color/Form:

Hygroscopic oil|Viscous liquid|Clear viscous, somewhat hygroscopic liquid ... Some crystallization may occur on standing

ATC Code:

D03AX03|A - Alimentary tract and metabolism|D - Dermatologicals|S - Sensory organs

HScode:

2924199090

Categories:

Nutrition Supplements

Characteristics

PSA:

89.79

XLogP3:

-0.9

Appearance:

Transparent colorless to slightly yellow viscous liquid

Density:

1.2 g/cm³ @ Temp: 20 °C

Melting Point:

<25 °C

Boiling Point:

119 °C

Flash Point:

246.3ºC

Refractive Index:

1.495-1.502

Water Solubility:

In water, 1.6X10+6 mg/L at 25 deg C /miscible/ (est)

Storage Conditions:

-20ºC

Vapor Pressure:

1.5X10-8 mm Hg at 25 deg C (est)

Toxicity:

LD50 oral in mouse: 15gm/kg

Taste:

Slightly bitter taste

Henrys Law Constant:

Henry's Law constant = 2.8X10-11 cu cm/molec-sec at 25 °C (est)

Collision Cross Section:

144.7 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|141.49 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|144.1 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Experimental Properties:

The alcohol corresponding to pantothenic acid, with vitamin activity|Hydroxyl radical reaction rate constant = 2.7X10-11 cu cm/molec-sec at 25 °C (est)

See More (+)-Panthenol Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Dexpanthenol injection should be protected from freezing & excessive heat.

See More (+)-Panthenol Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Food additives,Pharmaceutical raw materials,Chemicals,Comestic raw materials

Location:
Room 501, Unit 6, No. 40, hushan road,Licang,Qingdao

Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2017

QINGDAO EASTCHEMSORCES TRADE LIMITED is a leading Manufactory supplier of Sorbitol, Citric acid, Sodium hypochlorite based in Qingdao, Shandong, China. With a commitment to quality and customer satisfaction, QINGDAO EASTCHEMSORCES TRADE LIMITED has become a trusted name in the industry. Our product line includes a range of high-quality Sorbitol, Citric acid, Sodium hypochlorite, which are available at competitive prices. QINGDAO EASTCHEMSORCES TRADE LIMITED has established itself as a reliable supplier of chemical products on the echemi.com.

Inquiry History

18 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Dexpanthenol	100 KG	Aug 8, 2025
Australia	D Panthenol (Provitamin B5)	1 L	Jan 13, 2026
Kenya	Panthenol Cosmetics	10 KG	Sep 8, 2025
India	D-Panthenol	500.00 KG	Jun 7, 2025
Turkey	DEKSPANTENOL (VİT B5)	10.00 KG	Apr 16, 2025
Russia	Dexpanthenol	250 KG	Dec 6, 2024
Russia	D-panthenol 75%	900 KG	Sep 16, 2024
India	D-panthenol 98%	500.00 KG	Jul 4, 2024
India	D-PANTHENOL 98% LIQUID	500.00 KG	Apr 3, 2024
India	D Panthenol	100 20' Fcl	Jun 9, 2025
Russia	Dexpanthenol	400 KG	Oct 16, 2024
India	d-panthenol	250.00 KG	Aug 9, 2024
India	D-panthenol	0.05 KG	Jun 12, 2024
India	d-panthenol 98%	600.00 KG	May 24, 2024
Bangladesh	Dexpanthenol	1.00 KG	Nov 11, 2023
Poland	D-panthenol	1000 KG	Nov 21, 2024
Pakistan	Dexpanthenol	50 G	Oct 22, 2024
India	D Panthenol	50.00 G	Oct 9, 2023

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