pure Melanotan II powder used for increase skin melanin
5 Inquiries
91161-71-6
Pharmaceutical Grade
99%
qingdao
JF
g,kg
2025-10-03
Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceTerbinafine (TDT 067) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a Ki of 30 nM.
Solid
Terbinafine is a tertiary amine that is N-methyl-1-naphthalenemethylamine in which the amino hydrogen is replaced by a 3-(tertbutylethynyl)allyl group. An antifungal agent administered orally (generally as the hydrochloride salt) for the treatment of skin and nail infections. It has a role as an EC 1.14.13.132 (squalene monooxygenase) inhibitor, a P450 inhibitor and a sterol biosynthesis inhibitor. It is a tertiary amine, an acetylenic compound, a member of naphthalenes, an enyne and an allylamine antifungal drug. It is a conjugate base of a terbinafine(1+).|Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal. It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell wall synthesis pathway. Terbinafine hydrochloride was granted FDA approval on 30 December 1992.|Terbinafine is an Allylamine Antifungal.|Terbinafine is an orally and topically active allylamine fungicidal agent which is used to treat superficial fungal infections of the skin and nails. Terbinafine has been clearly linked to rare instances of acute liver injury that can be severe and sometimes fatal.|Terbinafine is a synthetic allylamine derivative with antifungal activity. Terbinafine exerts its effect through inhibition of squalene epoxidase, thereby blocking the biosynthesis of ergosterol, an important component of fungal cell membranes. As a result, this agent disrupts fungal cell membrane synthesis and inhibits fungal growth.|A naphthalene derivative that inhibits fungal SQUALENE EPOXIDASE and is used to treat DERMATOMYCOSES of the skin and nails.Basic Info-
Product Name:
Terbinafine
Other Name:1-Naphthalenemethanamine,N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-methyl-;1-Naphthalenemethanamine,N-(6,6-dimethyl-2-hepten-4-ynyl)-N-methyl-,(E)-;1-Naphthalenemethanamine,N-[(2E)-6,6-dimethyl-2-hepten-4-ynyl]-N-methyl-;N-[(2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N-methyl-1-naphthalenemethanamine;SF 86-327;Terbinafine;Daskil;Lamasil;Eksifine;Mycoterbin;Fungoterbin;YY 1084;Terbisil;Terbinol;TDT 067;Tebina;DA 5505;97048-40-3
CAS No.:91161-71-6
Molecular Formula:C21H25N
InChIKeys:InChIKey=DOMXUEMWDBAQBQ-WEVVVXLNSA-N
Molecular Weight:291.44
Exact Mass:291.43
EC Number:245-385-8
UNII:G7RIW8S0XP
DSSTox ID:DTXSID2023640
NCI Thesaurus Code:C48019
ATC Code:QS02CA90|D01AE15|D - Dermatologicals
HScode:2921499090
Categories:
Characteristics-
PSA:
3.2
XLogP3:5.6
Appearance:Solid
Density:1.0±0.1 g/cm3
Melting Point:203-205 °C
Boiling Point:417.9°C at 760 mmHg
Flash Point:183.7±22.3 °C
Refractive Index:1.586
Water Solubility:7.38e-04 g/L
PKA:7.1None
Dissociation Constants:7.10
Collision Cross Section:187.2 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]
Research-
Class:
Synthetic cyclic heptapeptide / non-selective melanocortin receptor agonist
Status:Research compound — NOT FDA approved. FDA issued warning letters. WADA banned substance.
Mechanism:A synthetic cyclic heptapeptide (Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂) analog of α-MSH. Melanotan II is a high-affinity non-selective agonist at MC1R, MC3R, MC4R, and MC5R. MC1R activation induces melanogenesis (skin darkening/tanning); MC4R activation affects sexual function, appetite suppression, and energy homeostasis. Carries significant safety risks including nausea, hypertension, and priapism.
EC50 (Human Mc1r Ki):1.2 nM
EC50 (Human Mc5r Ki):1.0 nM
EC50 (Human Mc3r Ki):1.1 nM
EC50 (Human Mc4r Ki):2.1 nM
Source:Wikberg JES, et al. Pharmacol Res. 2000;42(5):393–420. PubChem CID 92432.DOI
Clinical Development:
References-
ChEMBL:
CHEMBL363210
PubChem:Literature:FDA Warning Letters: Melanotan II (unapproved drug); WADA Prohibited List: Melanotan II (S2 hormone modulator)
Disclaimer:Melanotan II is NOT FDA-approved. The FDA has issued multiple warning letters to companies illegally selling Melanotan II as an unapproved new drug. It is also listed on the WADA Prohibited List as a banned substance in sport. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
Hazard IdentificationClassification of the substance or mixture
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H400 Very toxic to aquatic life
H410 Very toxic to aquatic life with long lasting effects
Precautionary statement(s) Prevention P273 Avoid release to the environment.
Response P391 Collect spillage.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332
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Location:
Unit D01,3/F., Wong King Industrial Building,No.2 Tai Yau Street, Kowloon
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7
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Total Annual Revenue:
$50 million-$100 million
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Total Employees:
51-100
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Year of Establishment:
2012
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Inquiry History5 Inquiries
Country Product Purchase Quantity Date Posted
United States
terbinafine
1 G Mar 13, 2026
United States
Terbinafine
20 MT Dec 30, 2023
Argentina
terbinafine
1 KG Oct 9, 2025
United States
Terbinafine
1 KG Oct 1, 2024
United States
Lamisil
5 KG Jan 5, 2024 Post an enquiry for this product