Baclofen 1134-47-0
KOSHER ISO FDA 7 Inquiries
1134-47-0
Pharmaceutical Grade
99%
shenzhen
Flying
1kg
2025-10-06
vitamin
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceWhite powder. Melting point: 206-208 °C. Dissolve using hot water, the aqueous solution was neutral, almost insoluble in alcohol, ether, acetone and other organic solvents, easily soluble in acidic, alkaline aqueous solution. The melting point of Chlorobenzene aminobutyric acid hydrochloride: 179-181 °C. Off-White SolidChEBI: A monocarboxylic acid that is butanoic acid substituted by an amino group at position 4 and a 4-chlorophenyl group at position 3. It acts as a central nervous system dep
Baclofen appears as odorless or practically odorless white to off-white crystalline powder. (NTP, 1992)|Solid
Baclofen appears as odorless or practically odorless white to off-white crystalline powder. (NTP, 1992)|Baclofen is a monocarboxylic acid that is butanoic acid substituted by an amino group at position 4 and a 4-chlorophenyl group at position 3. It acts as a central nervous system depressant, GABA agonist and muscle relaxant. It has a role as a muscle relaxant, a central nervous system depressant and a GABA agonist. It is a monocarboxylic acid, a primary amino compound, a member of monochlorobenzenes and a gamma-amino acid.|Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant used for the relief of painful and uncomfortable muscle spasms caused by a variety of conditions. It is known to be particularly useful in treating muscle spasticity associated with spinal cord injury. This drug has recently been studied for the management of alcohol withdrawal, however, a conclusion has not been made regarding baclofen efficacy in this condition,,. This drug was initially approved by the FDA in 1992. It is available in tablet form, injection form, and powder form (for suspension).|Baclofen is a centrally acting muscle relaxant commonly prescribed for spasticity in patients with multiple sclerosis. Baclofen has not been linked to rare instances of mild, self-limited, clinically apparent liver injury.|A GAMMA-AMINOBUTYRIC ACID derivative that is a specific agonist of GABA-B RECEPTORS. It is used in the treatment of MUSCLE SPASTICITY, especially that due to SPINAL CORD INJURIES. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission.CertificatesBasic Info-
Product Name:
Baclofen
Other Name:Benzenepropanoic acid,β-(aminomethyl)-4-chloro-;Hydrocinnamic acid,β-(aminomethyl)-p-chloro-;β-(Aminomethyl)-4-chlorobenzenepropanoic acid;β-(Aminomethyl)-p-chlorohydrocinnamic acid;β-(4-Chlorophenyl)-γ-aminobutyric acid;Baclofen;Lioresal;Ba 34647;β-(p-Chlorophenyl)-γ-aminobutyric acid;β-p-Chlorophenyl-GABA;CIBA Ba 34647;4-Amino-3-(4-chlorophenyl)butyric acid;C 34647Ba;4-Amino-3-(p-chlorophenyl)butyric acid;DL-4-Amino-3-p-chlorophenylbutanoic acid;dl-Baclofen;(±)-Baclofen;DL-Baclofen;Baclon;4-Amino-3-(4-chlorophenyl)butanoic acid;(±)-4-Amino-3-(4-chlorophenyl)butanoic acid;62594-36-9
CAS No.:1134-47-0
Molecular Formula:C10H12ClNO2
InChIKeys:InChIKey=KPYSYYIEGFHWSV-UHFFFAOYSA-N
Molecular Weight:213.66
Exact Mass:213.66
EC Number:214-486-9
NSC Number:755906|329137
UN Number:2811
DSSTox ID:DTXSID5022641
ATC Code:M03BX01|M - Musculo-skeletal system
HScode:2922492050
Categories:
Characteristics-
PSA:
63.3
XLogP3:-1
Appearance:white to very faintly yellow solid
Density:1.2069 (rough estimate)
Melting Point:206-208 °C
Boiling Point:364.3±32.0 °C(Predicted)
Flash Point:174.1±25.1 °C
Refractive Index:1.5500 (estimate)
Water Solubility:soluble in dilute NaOH or dilute HCl. soluble in water at approximately 4mg/ml at pH 7.6;1 M HCl: 50 mg/mL
Storage Conditions:2-8°C
Toxicity:Oral-rat LD50; 145 mg/kg; Oral-Mouse LD50: 200 mg/kg
Flammability characteristics:Flammable; burning produces toxic nitrogen oxides and chloride fumes; patients taking side effects: low blood pressure, reduced pulse, muscle weakness
PKA:9.62+ 0.1 (amino group) and 3.87 + 0.1 (carboxyl group)
Dissociation Constants:9.62 + 0.1 (amino group) and 3.87 + 0.1 (carboxyl group)
Collision Cross Section:149.2 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]
Air and Water Reactions:Insoluble in water.
Reactive Group:Acids, Carboxylic
Reactivity Profile:BACLOFEN is an amine. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
Skin irritation, Category 2
Skin sensitization, Category 1
Eye irritation, Category 2
Respiratory sensitization, Category 1
Specific target organ toxicity â single exposure, Category 3
Reproductive toxicity, Category 1B
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
H315 Causes skin irritation
H317 May cause an allergic skin reaction
H319 Causes serious eye irritation
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335 May cause respiratory irritation
H360 May damage fertility or the unborn child
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P284 [In case of inadequate ventilation] wear respiratory protection.
P271 Use only outdoors or in a well-ventilated area.
P203 Obtain, read and follow all safety instructions before use.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P333+P317 If skin irritation or rash occurs: Get medical help.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P342+P316 If experiencing respiratory symptoms: Get emergency medical help immediately.
P319 Get medical help if you feel unwell.
P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
vitamin
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Location:
Room 2-502, Building 6, Luneng Tehran Garden Building, No.8 Changbin Road, Xiuying district, Haikou City, Hainan Province
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Payment Terms:
TT against copy of documents,TT against B/L draft before shipment
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Average lead Time:
25
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
Less than 5
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Year of Establishment:
2023
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Inquiry History7 Inquiries
Country Product Purchase Quantity Date Posted
United States
Baclofen
300 G Aug 25, 2026
United States
Baclofen powder
10 KG Nov 28, 2023
Bangladesh
Baclofen
1 KG Sep 9, 2024
United States
baclofen
1 KG Jan 2, 2024
Netherlands
Baclofen
1 KG Nov 26, 2024
United States
Baclofen
1 KG Mar 21, 2024
Egypt
Baclofen
50 KG Sep 18, 2023 Post an enquiry for this product