 Home > Pharmaceutical Intermediates > Antineoplastics > Mutated EGFR-IN-1 for Sale > N1-[2-(Dimethylamino)ethyl]-5-methoxy-N1-methyl-N4-[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]-1,2,4-benzenetriamine RC07149

N1-[2-(Dimethylamino)ethyl]-5-methoxy-N1-methyl-N4-[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]-1,2,4-benzenetriamine RC07149

Name: N1-[2-(Dimethylamino)ethyl]-5-methoxy-N1-methyl-N4-[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]-1,2,4-benzenetriamine RC07149
Brand: Royalchem
SKU: pr2509081290
Price: 1 USD
Availability: InStock

1 Inquiries

Unit Price:

$1/KG EXW

Get Latest Price 

CAS No.:

1421372-66-8

Grade:

Industrial Grade

Content:

99%

Brand:

Royalchem

Packaging:

25kg/drum

Sample Available:

Yes

Price valid (until):

2030-01-01

Contact Supplier

 Chat Now

Hangzhou Royalchem Co.,LTD

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

14 days

Qualification:

Main Products:

Pharmaceutical intermediates

 Visit Store

Product Description
Seller Information
Inquiry History

Description

Product Detail

Manufacturer: Hangzhou Royalchem Co.,LTD.

Website: www.cnroyalchem.com

Hangzhou Royalchem Co., Ltd. was founded by a senior team with profound professional backgrounds in the chemical field, focusing on providing comprehensive chemical products and services. Its business scope covers a wide range, including the sales of core chemical products such as pharmaceutical raw materials and intermediates, food/feed additives, specialty chemicals, dyes & pigments, new catalytic materials, chemical reagents, engineering plastics and synthetic resins. It also engages in the sales of daily chemicals, containers, and import-export business, meeting the needs of clients across multiple sectors. Leveraging the technical accumulation of its professional team and strict quality control, the company has established a stable cooperation network in domestic and international markets. It not only provides high-quality raw material support for industries but also promotes global chemical resource circulation through import-export operations. Adhering to the philosophy of "win-win cooperation," Hangzhou Royalchem Co., Ltd. takes professionalism and integrity as its cornerstone, and sincerely looks forward to working with global partners to drive high-quality development in the chemical industry.

Hangzhou Royalchem Co., Ltd. Is focus on services on CMO & CDMO

Esterification, saponification, hydrolysis, alkylation, halogenation, acetylation, pressurized hydrogenation, and other reactions .

Preparation and separation of various impurities .

Development of preparation and purification production processes, salt conversion, liquid preparation post-treatment, etc.

Items	Specifications

ECHEMI Editorial Reference

Mutated EGFR-IN-1 is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating mutant and T790M resistance mutant.IC50 value:Target: Mutated EGFR inhibitorMore information can be found in Patent WO 2013014448 A1.2 - (2, 4, 5 - substituted -anilino) pyrimidine derivatives as egfr modulators useful for treating cancer.

Basic Info

Product Name:

Mutated EGFR-IN-1

Other Name:

HY-78869

CAS No.:

1421372-66-8

Molecular Formula:

C25H31N7O

InChIKeys:

HTNTZPBKKCORTP-UHFFFAOYSA-N

Molecular Weight:

445.57

Exact Mass:

445.259003

Categories:

Antineoplastics

Characteristics

PSA:

84.5

XLogP3:

3.3

Density:

1.21±0.1 g/cm3(Predicted)

Boiling Point:

676.5±65.0 °C(Predicted)

Flash Point:

363.0±34.3 °C

Refractive Index:

1.635

See More Mutated EGFR-IN-1 Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Mutated EGFR-IN-1 Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceutical intermediates

Location:
Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou

Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
14 days

Total Annual Revenue:
Less than $1 million

Total Employees:
Less than 5

Year of Establishment:
2025

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
Turkey	Pazopanib indazol	60 KG	Mar 31, 2026

Post an enquiry for this product

More Choices Find All Products for Sale 

Product Name	Grade / Content	Price	Supplier Name	Details
AZD9291 Osimertinib Intermediate CAS 1421372-66-8	Pharmaceutical Grade/99	$29.7-31.68/KG EXW	Wuhan Oner Biotech Co.,Ltd.	Inquiry
Mutated EGFR-IN-1	/99.00		HANGZHOU LEAP CHEM CO., LTD.	Inquiry
1421372-66-8	/		Guangzhou Yaoguang Technology Co., Ltd.	Inquiry
Mutated EGFR-IN-1 98% white powder LKLX	Industrial Grade/98		Shandong zhishang chemical Co.,Ltd	Inquiry
AZD9291 intermediate 99% Powder Industrial Grade C25H31N7O Top Purity Senwayer	Industrial Grade/99		Dingwang Technology (Wuhan) Co., Ltd.	Inquiry

N1-[2-(Dimethylamino)ethyl]-5-methoxy-N1-methyl-N4-[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]-1,2,4-benzenetriamine RC07149

Product Description

Seller Information