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AZD9291 Osimertinib Intermediate CAS 1421372-66-8

Name: AZD9291 Osimertinib Intermediate CAS 1421372-66-8
Brand: ONERBIO
SKU: pr2303031368
Price: 30.3 USD
Availability: InStock

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CAS No.:

1421372-66-8

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai, Beijing

Brand:

ONERBIO

Packaging:

25kg/drum

Price valid (until):

2026-06-27

Contact Supplier

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Wuhan Oner Biotech Co.,Ltd.

Company Type:

Distributor

Location:

China

Qualification:

Main Products:

Nutrition supplement material,Pharmaceutical raw material,Chemical raw material

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Product Description
Seller Information
Inquiry History

Description

Product Name: Mutated EGFR-IN-1
Synonyms: AZD9291
CAS: 1421372-66-8
MF: C25H31N7O
MW: 445.56

Appearance: White powder

Product：	AZD9291	Batch No：	ONB2220210710
Date of Manufacture：	2021-07-10	Quantity：	10KG
Date of Certificate：	2021-07-14	CAS:	1421372-66-8
Date of Expire:	2023-07-13	Reference	In House
Items	Requirements		Results
Appearance	White powder		Conformity
Assay（w/w, HPLC）	>98.0%		99.3%
Water content（by KF）	<1.0%		0.19%
Optical rotation	-34.0° 〜-30.0°		-33.2°
Heavy metal content(pb)	≤10ppm		Confirm
Pb	≤ 0.5 ppm		Not detected
As	≤ 0.5 ppm		0.005 ppm
Hg	≤ 0.1 ppm		Not detected
Cd	≤ 0.5 ppm		Not detected
Residue on ignition	<0.2%		<0.11%
Total microbial count (GB 4783.2)	≤ 750 CFU/g		Not detected
Ethanol ( by GC)	≤ 5000 ppm		141 ppm
Conclusion	Analysis according to in-house SP, Confirm.

Osimertinib intermediate(AZD-9291):

CAS: 1421372-94-2, N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine

CAS: 1421372-67-9, N1-[2-(Dimethylamino)ethyl]-5-methoxy-N1-methyl-N4-[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]-2-nitro-1,4-benzenediamine

CAS: 1421372-66-8, N1-[2-(Dimethylamino)ethyl]-5-methoxy-N1-methyl-N4-[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]-1,2,4-benzenetriamine

Basic Info

Product Name:

Mutated EGFR-IN-1

Other Name:

HY-78869

CAS No.:

1421372-66-8

Molecular Formula:

C25H31N7O

InChIKeys:

HTNTZPBKKCORTP-UHFFFAOYSA-N

Molecular Weight:

445.57

Exact Mass:

445.259003

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

84.5

XLogP3:

3.3

Density:

1.21±0.1 g/cm3(Predicted)

Boiling Point:

676.5±65.0 °C(Predicted)

Flash Point:

363.0±34.3 °C

Refractive Index:

1.635

See More Mutated EGFR-IN-1 Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Mutated EGFR-IN-1 Safety Data Sheet 

Seller Information

Business Type:
Distributor

Main Products:
Nutrition supplement material,Pharmaceutical raw material,Chemical raw material

Location:
Changqing 5th Road, Jianghan District

Payment Terms:
TT against copy of documents

Average lead Time:
5

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
5-10

Year of Establishment:
2020

Wuhan Oner Biotech Co.,Ltd. located in the popular city of Wuhan, specilize in producing and developing pharmaceutical & its intermediates, Cosmetics Raw Material and Intermediate, food additive, Plant extracts,and in distributing the products of our own company. We serves our clients by supplying high-quality.These products are manufactured in ISO 9001 certified plants and have continuously been passing quality inspection by CIQ (China Entry & Exit Inspection and Quarantine Bureau),100% pass rate. Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , the products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc. With constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
Turkey	Pazopanib indazol	60 KG	Mar 31, 2026

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