Sumatriptan succinate 103628-48-4
103628-48-4
Pharmaceutical Grade
99%
shenzhen
Flying
1kg
2025-10-09
vitamin
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceWhite Crystalline PowderChEBI: A succinate salt obtained by reaction of sumatriptan with one equivalent of succinic acid. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used for the acute treatm nt of migraine with or without aura in adults.Sumatriptan succinate is a synthetic drug belonging to a class of medications known as 5-hydroxytryptamine agonists (also called ''triptans''), which is commonly used to treat cluster and migraine headaches
Sumatriptan succinate is a succinate salt obtained by reaction of sumatriptan with one equivalent of succinic acid. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used for the acute treatment of migraine with or without aura in adults. It has a role as a serotonergic agonist and a vasoconstrictor agent. It contains a sumatriptan(1+).|Sumatriptan Succinate is the succinate salt form of sumatriptan, a member of the triptan class of compounds with anti-migraine property. Sumatriptan succinate selectively binds to and activates serotonin 5-HT1 receptors. This results in constriction of meningeal, dural, cerebral or pial blood vessels via stimulation of the 5-HT1B receptors, thereby reducing the vascular pulsation and may provide relief in migraine headaches. Furthermore, agonistic action of this agent through presynaptic stimulation of 5-HT1D and/or 5-HT1F receptors prevents release of vasoactive and pro-inflammatory neuropeptide (calcitonin gene-related peptide), thereby may also relieve migraine headaches. In addition, central inhibition of pain transmission via the inhibition of trigeminal neurons in the brain stems and upper spinal cord mediated by 5-HT1B, 5-HT1D or 5-HT 1F receptors also aides in the alleviation of migraine pain.|A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.Basic Info-
Product Name:
Sumatriptan succinate
Other Name:Butanedioic acid,compd. with 3-[2-(dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide (1:1);1H-Indole-5-methanesulfonamide,3-[2-(dimethylamino)ethyl]-N-methyl-,butanedioate (1:1);Sumatriptan succinate;GR 43175C;Imigran;Imitrex;Imigrane;Sumitrex;Migragesin;Megrelan;Imiject;Treximet;Sumagraine;Suminat;1-[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]-N-methylmethanesulfonamide butanedioic acid
CAS No.:103628-48-4
Molecular Formula:C14H21N3O2S.C4H6O4
InChIKeys:InChIKey=PORMUFZNYQJOEI-UHFFFAOYSA-N
Molecular Weight:413.49
Exact Mass:341.140930
EC Number:1308068-626-2
UNII:J8BDZ68989
NSC Number:760362
DSSTox ID:DTXSID60145966
NCI Thesaurus Code:C29470
HScode:29350090
Categories:
Characteristics-
PSA:
148
XLogP3:2.72870
Appearance:white to off-white
Density:1.2±0.1 g/cm3
Melting Point:165-166 °C
Boiling Point:647.2°C at 760 mmHg
Flash Point:254.8ºC
Refractive Index:1.552
Water Solubility:H2O: >20mg/mL
Storage Conditions:Store at +4°C
Vapor Pressure:7.05X10-9 mm Hg at 25 deg C (est)
Hazard IdentificationClassification of the substance or mixture
Serious eye damage, Category 1
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H318 Causes serious eye damage
Precautionary statement(s) Prevention P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P317 Get medical help.
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
vitamin
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Location:
Room 2-502, Building 6, Luneng Tehran Garden Building, No.8 Changbin Road, Xiuying district, Haikou City, Hainan Province
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Payment Terms:
TT against copy of documents,TT against B/L draft before shipment
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Average lead Time:
25 days
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
Less than 5
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Year of Establishment:
2023
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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