Buspirone hydrochloride 99.0%Min RC01032
33386-08-2
Pharmacy Grade
99%
中国
Royalchem
25kg/drum
2025-12-31
Pharmaceutical intermediates
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceBuspirone hydrochloride is an anxiolytic psychotropic drug, is used to treat generalized anxiety disorder (GAD).
Buspirone hydrochloride is a hydrochloride salt resulting from the reaction of equimolar amounts of buspirone and hydrogen chloride. It has a role as an anxiolytic drug, an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor, a sedative and a serotonergic agonist. It contains a buspirone(1+).|Buspirone Hydrochloride is the hydrochloride salt of an anxiolytic agent chemically and pharmacologically unrelated to benzodiazepines, barbiturates, or other sedative/hypnotic drugs. Although its exact mechanism of action is unknown, buspirone may exert its anti-anxiety effects via serotonin (5-HT1A) and dopamine receptors (D2) and may indirectly affect other neurotransmitter systems. Unlike typical benzodiazepine anxiolytics, this agent does not exert anticonvulsant or muscle relaxant effects and lacks prominent sedative effects.|An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.Basic Info-
Product Name:
Buspirone hydrochloride
Other Name:8-Azaspiro[4.5]decane-7,9-dione,8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-,hydrochloride (1:1);8-Azaspiro[4.5]decane-7,9-dione,8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-,monohydrochloride;1,1-Cyclopentanediacetimide,N-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-,monohydrochloride;8-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride;MJ 9022-1;Buspirone hydrochloride;Buspirone monohydrochloride;Bespar;Buspar;Axoren;Buspimem;Ansiced;Narol;Censpar;Buspinol;Travin;Buspisal;Ansial;Lucelan;Buspa;Ansiten;Buscalma;Busron
CAS No.:33386-08-2
Molecular Formula:C21H31N5O2.ClH
InChIKeys:InChIKey=RICLFGYGYQXUFH-UHFFFAOYSA-N
Molecular Weight:421.96
Exact Mass:421.22400
EC Number:251-489-4
UNII:207LT9J9OC
NSC Number:759571|751138
DSSTox ID:DTXSID1037193
NCI Thesaurus Code:C26641
HScode:2933990090
Categories:
Characteristics-
PSA:
69.6
XLogP3:2.83100
Appearance:white solid
Density:1.24g/cm3
Melting Point:201.5-202.5 °C
Boiling Point:613.9ºC at 760mmHg
Flash Point:9℃
Water Solubility:Soluble in methanol (50 mg/ml), water (partly), DMSO (100 mM).
Storage Conditions:2-8°C
Toxicity:LD50 i.p. in rats: 136 mg/kg (Allen)
Collision Cross Section:197.7 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceutical intermediates
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Location:
Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
14
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Total Annual Revenue:
Less than $1 million
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Total Employees:
Less than 5
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Year of Establishment:
2025
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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