Scopolaminee
84 Inquiries
51-34-3
shanghai
10mg/bottle
2025-10-16
Dichloromethane,Linocaine hydrochloride
-
Product Description
-
Seller Information
-
Inquiry History
-
DescriptionECHEMI Editorial ReferenceScopolamine is a high affinity (nM) muscarinic antagonist. 5-HT3 receptor-responses are reversibly inhibited by Scopolamine with an IC50 of 2.09 μM.
LSM-1330 is a 3-hydroxy carboxylic acid.|Scopolamine as a natural plant alkaloid that has potent anticholinergic effects and is used to treat mild to moderate nausea, motion sickness and allergic rhinitis. Scopolamine has not been implicated in causing liver enzyme elevations or clinically apparent acute liver injury.|An alkaloid from SOLANACEAE, especially DATURA and SCOPOLIA. Scopolamine and its quaternary derivatives act as antimuscarinics like ATROPINE, but may have more central nervous system effects. Its many uses include an anesthetic premedication, the treatment of URINARY INCONTINENCE and MOTION SICKNESS, an antispasmodic, and a mydriatic and cycloplegic.
White or almost white, crystalline powder or colourless crystals.
Scopolamine is the main active ingredient of Scopolia japonica, Datura metel L., and other Solanaceae plants. As early as 1892, the chemist E.Schmidt first isolated it from the Scopolia japonica, so named it as scopolamine. Due to its obvious deficiencies in solubility and usage, the researchers modified its structure as scopolamine butylbromide, which was synthesized and used scopolamine and bromo-n-butane with heating refluxing method. Preparation method of scopolamine butylbromide is simple, and it’s easy to be synthesized. There are about 170 domestic enterprises producing its raw materials currently.European Pharmacopoeia (9th ed.), United States Pharmacopeia (36), and the Japanese Pharmacopoeia (16th ed.) contained bromine scopolamine; British Pharmacopoeia (2015) contained the raw materials and preparations of scopolamine butylbromide, including tablets and injections. Pharmacopoeia of the People’s Republic of China (2015) contained its raw materials, injection, and capsules.
ChEBI: A tropane alkaloid that is the (S)-tropic acid ester of 6beta,7beta-epoxy-1alphaH,5alphaH-tropan-3alpha-ol.Basic Info-
Product Name:
Scopolamine
Other Name:6,7-Epoxytropine tropate;Benzeneacetic acid, .alpha.-(hydroxymethyl)-, (1.alpha.,2.beta.,4.beta.,5.alpha.,7.beta.)-9-methyl-3-oxa-9-azatricyclo3.3.1.02,4non-7-yl ester, (.alpha.S)-;1aH,5aH-Tropan-3a-ol, 6b,7b-epoxy-, (-)-tropate (ester) (8CI);3-Oxa-9-azatricyclo[3.3.1.02,4]nonane, benzeneacetic acid deriv.;6b,7b-Epoxy-3a-tropanyl S-(-)-tropate;9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol (-)-tropate;Atrochin;Atroquin
CAS No.:51-34-3
Molecular Formula:C17H21NO4
InChIKeys:InChIKey=STECJAGHUSJQJN-FWXGHANASA-N
Molecular Weight:303.35
Exact Mass:303.35
EC Number:200-090-3
DSSTox ID:DTXSID6023573
Color/Form:White to off-white
ATC Code:A - Alimentary tract and metabolism|N - Nervous system|S - Sensory organs
HScode:29399990
Categories:
Characteristics-
PSA:
62.30000
Physical Properties:Appearance: a kind of viscous liquid, brown color. Solubility: soluble in ethanol, ethyl ether, chloroform, acetone, and water, very soluble in hot water, slightly soluble in benzene and petroleum ether, and also soluble in cold water. It can generate various crystals with multiple inorganic or organic acids. Melting point: 59±1.0°C
XLogP3:0.76
Appearance:White crystalline powder
Density:1.31
Melting Point:59 ºC
Boiling Point:444.28°C (rough estimate)
Flash Point:232.2℃
Refractive Index:1.5022 (estimate)
Water Solubility:95g/L(15 ºC)
Storage Conditions:-20°C
Vapor Pressure:7.18X10-9 mm Hg at 25 °C (est)
Toxicity:A belladonna plant alkaloid that exerts its pharmacodynamic effects by blocking muscarinic acetylcholine receptor sites. The s.c. LD50 of scopolamine hydrobromide in mice is 3.8 g/kg. Scopolamine crosses the blood brain barrier, and its antimuscarinic effects include, in therapeutic doses, drowsiness, euphoria, amnesia, fatigue, loss of REM sleep and, at higher doses, restlessness or even delirium. Scopolamine can be used to treat motion sickness and parkinsonian tremor. The effects of scopolamine may be greater in the CNS than atropine, and it may be a better antidote for organophosphate intoxication.
Flammability characteristics:Combustible; Fire breaks down toxic nitrogen oxide fumes
Specific rotation:D20 -28° (c = 2.7)
PKA:7.55-7.81(at 25℃)
Henrys Law Constant:Henry's Law constant = 3.36X10-16 atm-cu m/mol at 25 °C (est)
Dissociation Constants:pKa = 7.75
Experimental Properties:Crystals. Freely soluble in water, dilute alcohol; slightly soluble in absolute alcohol /Methyl nitrate/|Dihydrate: chisel-shaped prisms from ethanol+water, mp 38-40 °C. Monohydrate: efflorescent crystals, mp 55-57 °C. Anhydrous: long prisms, mp 82-82 °C. Very slightly soluble in water; soluble in alcohol, chlorform, ether, oils /DL-form/|ODORLESS /SCOPOLAMINE HYDROBROMIDE USP/|COLORLESS OR WHITE CRYSTALS OR WHITE GRANULAR POWDER /SCOPOLAMINE HYDROBROMIDE NF/|Hydroxyl radical reaction rate constant = 5.97X10-11 cy cm/molec-sec at 25 °C (est)
Critical Temperature & Pressure:-20°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 2, Oral
Acute toxicity - Category 1, Dermal
Acute toxicity - Category 2, Inhalation
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H300 Fatal if swallowed
H310 Fatal in contact with skin
H330 Fatal if inhaled
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P262 Do not get in eyes, on skin, or on clothing.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P284 [In case of inadequate ventilation] wear respiratory protection.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P316 Get emergency medical help immediately.
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P320 Specific treatment is urgent (see ... on this label).
Storage P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
-
-
Seller Information
-
Business Type:
Manufactory
-
Main Products:
Dichloromethane,Linocaine hydrochloride
-
Location:
BUILDING 1,HISENSE INTELLIGENCE VALLEY,NO.2116,OF PHOEIX ROAD, HIGH-TECH ZONE ,JINAN CITY ,SHANDONG PROVINCE,CHINA
-
Payment Terms:
D/P,L/C,D/A
-
Average lead Time:
15
-
Total Annual Revenue:
$10 million-$25 million
-
Total Employees:
11-50
-
Year of Establishment:
2016
-
-
Inquiry History84 Inquiries
Country Product Purchase Quantity Date Posted 
Bangladesh
Scopolamine CAS 51-34-3 99%
1 KG Oct 30, 2023 
United States
Scopolamine 99.9% Powder 51-34-3 DW
50 MT Oct 19, 2023
Bangladesh
Factory price CAS 51-34-3 Scopolamine powder
100 G Nov 6, 2023
Bangladesh
Safe Delivery Scopolamine 99% Solid CAS 51-34-3
01850035067 MT Oct 14, 2023
Bangladesh
Safe Delivery Scopolamine 99% Solid CAS 51-34-3
10 G Nov 4, 2023
Bangladesh
Safe Delivery Scopolamine 99% Solid CAS 51-34-3
10 G Oct 21, 2023
Bangladesh
Safe Delivery Scopolamine 99% Solid CAS 51-34-3
100 G Oct 12, 2023
Bangladesh
Safe Delivery Scopolamine 99% Solid CAS 51-34-3
1 KG Oct 10, 2023
Bangladesh
Safe Delivery Scopolamine 99% Solid CAS 51-34-3
1 KG Oct 17, 2023 
France
Scopolamine hot sale CAS 51-34-3 wholesale Scopolamine powder
1 G Nov 6, 2023
United States
Scopolamine hot sale CAS 51-34-3 wholesale Scopolamine powder
5 G Sep 22, 2023
Bangladesh
Best price scopolamin 99% cas 51-34-3 pure scopolamine Hyoscine
20 G Nov 9, 2023
France
Scopolamine hot sale CAS 51-34-3 wholesale Scopolamine powder
1 G Oct 30, 2023
Bangladesh
Scopolamine 99% white powder 51-34-3 99% White A Scopolamine 99%
10 G Dec 30, 2024
France
China Factory Sell 99% Scopolamine powder/ pure Scopolamine / API Scopolamine 51-34-3
10 G Oct 24, 2023
Bangladesh
Scopolamine
100 KG Apr 22, 2025
Bangladesh
Scopolamine
1 KG May 21, 2026
Bangladesh
Scopolamine powder
10 G Sep 8, 2025
France
Scopolamine
100 KG Jul 3, 2024 
South Africa
Scopolamine powder
500 MG Apr 22, 2024 Post an enquiry for this product