Synthetic Polypeptide Bremelanotide Acetate For Medical Research & Cosmetic Raw Materials

Bremelanotide Acetate More Info

Bremelanotide Acetate is a synthetic cyclic heptapeptide analog of α-melanocyte-stimulating hormone (α-MSH). Its development originated from research into melanocortin receptors, specifically targeting the MC1R and MC4R subtypes. Initially investigated for its potential photoprotective effects, clinical trials revealed a distinct side effect of spontaneous penile erection, which redirected its development towards sexual dysfunction. The acetate salt form is used to enhance the stability and solubility of the peptide for pharmaceutical formulation. Its mechanism of action involves acting as a non-selective agonist of melanocortin receptors, with its activity at the MC4R receptor in the central nervous system being primarily responsible for its therapeutic effects on sexual arousal.

Uses and Applications

The primary and approved application of Bremelanotide Acetate is in the therapeutic management of hypoactive sexual desire disorder (HSDD) in premenopausal women. It is the first FDA-approved on-demand treatment for this condition, administered as a subcutaneous auto prior to anticipated sexual activity. Its effect is believed to be mediated through the activation of central pathways in the brain that modulate sexual response, rather than through direct hormonal mechanisms. Outside of its approved use, it has been studied for the treatment of erectile dysfunction and female sexual arousal disorder, and it is also encountered in research contexts as a tool for studying melanocortin receptor physiology and pharmacology.

Application Market

The market for Bremelanotide Acetate is a highly specialized and premium niche within the women's health pharmaceutical sector. It is marketed under the brand name Vyleesi® and is positioned as a novel, on-demand therapeutic option, distinguishing it from daily oral medications. The market is primarily concentrated in the United States following its FDA approval, with potential for expansion into other regulated markets. Distribution is tightly controlled through specialty pharmacies and prescription channels, targeting healthcare providers who specialize in women's health or sexual medicine. As a patented, branded biologic peptide, it represents a high-cost therapy, and its market penetration is influenced by insurance coverage and reimbursement policies rather than being a broad-volume commodity.

Important Considerations

Bremelanotide Acetate is a potent prescription-only medication with specific safety considerations. Its administration can cause transient increases in blood pressure and a high incidence of nausea, which often necessitates antiemetic premedication. It is contraindicated in patients with uncontrolled hypertension or known cardiovascular disease. A notable side effect is the potential for hyperpigmentation (darkening of the skin and gums), which may not be fully reversible. In an industrial setting, handling the pure peptide API requires stringent containment procedures and personal protective equipment (PPE) to prevent occupational exposure through inhalation or skin contact. It is for use only in the finished, sterile dosage form and must be administered under a healthcare provider's guidance with appropriate patient screening.

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FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

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Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

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Suitable for more than 50kg 
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Suitable for more than 500kg      
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Q5. What HyperChem will provide after shipment?

For sample orders: 
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1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
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HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.