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Cephradine 38821-53-3

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CAS No.:

38821-53-3

Grade:

Pharmaceutical Grade

Content:

98%

Port:

SHANGHAI

Packaging:

25KG

Price valid (until):

2025-12-31

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Chong Da Prostaglandin Fine Chemicals Co., Ltd

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

prostaglandins,Polymyxin B sulfate,Clemizole hydrochloride,1,4-Diacetylbenzene,Estradiol valerate ,IMD 0354

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Cephradine (Cefradine) is a broad-spectrum and orally active cephalosporin. Cephradine is active against both gram-positive and gram-negative pathogens. Cephradine is effective in eradicating most penicillinase-producing organisms. Cephradine has been used in the research of genitourinary, gastrointestinal and respiratory tract infections, and in infections of the skin and soft tissues. Cephradine blocks solar-ultraviolet induced skin inflammation through direct inhibition of TOPK^[1] ^[2] ^[3].

[1]. Schwinghammer TL, et al. Pharmacokinetics of cephradine administered intravenously and orally to young and elderly subjects. J Clin Pharmacol. 1990;30(10):893-899

[2]. Caloza DL Jr, et al. Intravenous use of cephradine and cefazolin against serious infections. Antimicrob Agents Chemother. 1979;15(1):119-122.

[3]. Fan X, et al. Cefradine blocks solar-ultraviolet induced skin inflammation through direct inhibition of T-LAK cell-originated protein kinase. Oncotarget. 2016;7(17):24633-24645

Basic Info

Product Name:

Cephradine

Other Name:

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2R)-2-amino-2-(1,4-cyclohexadien-1-yl)acetyl]amino]-3-methyl-8-oxo-,(6R,7R)-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[(amino-1,4-cyclohexadien-1-ylacetyl)amino]-3-methyl-8-oxo-,[6R-[6α,7β(R*)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2R)-amino-1,4-cyclohexadien-1-ylacetyl]amino]-3-methyl-8-oxo-,(6R,7R)-;(6R,7R)-7-[[(2R)-2-Amino-2-(1,4-cyclohexadien-1-yl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;Cephradin;Cefradine;Cephradine;7-[D-α-Amino-(1,4-cyclohexadienyl)acetamide]-3-desacetoxycephalosphoranic acid;Sefril;Velosef;SQ 11436;Eskacef;Cefro;Cefrag;Cesporan;Dimacef;Ecosporina;Anspor;Celex;Cefradex;Lisacef;Lenzacef;Velocef;Samedrin;Megacef;Easkacef;Cefradin

CAS No.:

38821-53-3

Molecular Formula:

C16H19N3O4S

InChIKeys:

InChIKey=RDLPVSKMFDYCOR-UEKVPHQBSA-N

Molecular Weight:

349.41

Exact Mass:

349.40

EC Number:

254-137-8

UNII:

9YA6SX5S4D

DSSTox ID:

DTXSID4022785

NCI Thesaurus Code:

C76181

Color/Form:

WHITE, CRYSTALLINE POWDER; POLYMORPHIC

ATC Code:

J - Antiinfectives for systemic use

HScode:

2941905400

Categories:

Other Chemical Drugs

Characteristics

PSA:

138

XLogP3:

0.4

Appearance:

Solid

Density:

1.5±0.1 g/cm3

Melting Point:

140 °C

Boiling Point:

898℃

Flash Point:

>110°(230°F)

Refractive Index:

1.684

Water Solubility:

soluble in water;1 M NH4OH: soluble 50mg/mL

Storage Conditions:

Store at 0-5°C

Dissociation Constants:

PKA1 ABOUT 2.6, PKA2 ABOUT 7.3

Experimental Properties:

MP 140-142 °C (DECOMP);PK1 = 2.63, PK2 = 7.57 /CEPHRADINE MONOHYDRATE/|SMALL, COLORLESS CRYSTALS /CEPHRADINE MONOHYDRATE/|Soluble in propylene glycol, slightly soluble in acetone, ethanol. Insoluble in ether, chloroform, benzene, hexane /Cephradine monohydrate/

See More Cephradine Properties 

Hazard Identification

Classification of the substance or mixture

Skin irritation, Category 2

Skin sensitization, Category 1

Eye irritation, Category 2

Respiratory sensitization, Category 1

Specific target organ toxicity â single exposure, Category 3

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H315 Causes skin irritation H317 May cause an allergic skin reaction H319 Causes serious eye irritation H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled H335 May cause respiratory irritation
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P284 [In case of inadequate ventilation] wear respiratory protection. P271 Use only outdoors or in a well-ventilated area.
Response	P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P333+P317 If skin irritation or rash occurs: Get medical help. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P342+P316 If experiencing respiratory symptoms: Get emergency medical help immediately. P319 Get medical help if you feel unwell.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Cephradine Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
prostaglandins,Polymyxin B sulfate,Clemizole hydrochloride,1,4-Diacetylbenzene,Estradiol valerate,IMD 0354

Location:
NO.1585 JIUYE ROAD, QINGPU DISTRICT, SHANGHAI, CHINA

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,100% TT in advance

Average lead Time:
7

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2011

Certifications:
ISO9001

Company Profile

Founded in 2018, Shanghai Chong Da Prostaglandin Fine Chemicals Co., Ltd. is a professional manufacturer committed to research, development and promotion of prostaglandin(PG) in both human medicine and animal health. The company also has a technical team with decades of experience in PG production.
Chong Da now has mature technology with a complete production chain, laboratory analysis system and strict product management mode,are responsible for sales as well as experiments and development of new products .
Our products are exported to more than 20 countries and regions, mainly in South America and Europe. The main products are: Cloprostenol Sodium, Latanoprost, Bimatoprost, Travoprost, Prostaglandin E1, E2, etc., and related derivatives, intermediates and extraction of impurities appearing in the production process.

Inquiry History

7 Inquiries

Country	Product	Purchase Quantity	Date Posted
Bangladesh	Cefradine Compacted	2500 KG	Nov 26, 2023
Bangladesh	Cefradine Compacted BP	2500 KG	Nov 26, 2023
Bangladesh	Cefradine Compacted BP	2500 KG	Nov 27, 2023
Bangladesh	Cefradin Compacted BP	2500 KG	Nov 28, 2023
Bangladesh	cephradine micronised	2000 KG	Apr 29, 2026
Pakistan	CEPHRADINE	1000 KG	Dec 31, 2025
Pakistan	CEPHRADINE	500 KG	Dec 30, 2025

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