Tizanidine hydrochloride RC02484
2 Inquiries
64461-82-1
Pharmaceutical Grade
99%
Royalchem
25kg/drum
2029-12-31
Pharmaceutical intermediates
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceTizanidine hydrochloride is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons.Target: α2-adrenergic receptorTizanidine is a drug that is used as a muscle relaxant. It is a centrally acting α2 adrenergic agonist. It is used to treat the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, ALS, spastic diplegia, back pain, or certain other injuries to the spine or central nervous system. It is
Tizanidine hydrochloride is a benzothiadiazole.|Tizanidine Hydrochloride is the hydrochloride salt form of tizanidine, an imidazoline derivative structurally similar to clonidine and an adrenergic agonist with muscle relaxant property. Tizanidine stimulates alpha-2 adrenergic receptors in the central nervous system, thereby inhibiting presynaptic release of norepinephrine and increasing the inhibitory effect on alpha motor neurons and motor reflexes. Tizanidine exerts some activity at the postsynaptic excitatory amino acid receptors and imidazoline receptors which may contribute to the overall reduction in facilitation of spinal motor neurons. Overall, tizanidine hydrochloride causes muscle relaxation, reduces spasticity and antinociceptive effects.Basic Info-
Product Name:
Tizanidine hydrochloride
Other Name:2,1,3-Benzothiadiazol-4-amine,5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-,hydrochloride (1:1);2,1,3-Benzothiadiazol-4-amine,5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-,monohydrochloride;5-Chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole hydrochloride;Sirdalud;Tizanidine hydrochloride;Zanaflex;AB 021;DS 103-282;Ternelin;AN 021;Tizan;Tizpa
CAS No.:64461-82-1
Molecular Formula:C9H8ClN5S.ClH
InChIKeys:InChIKey=ZWUKMNZJRDGCTQ-UHFFFAOYSA-N
Molecular Weight:290.17
Exact Mass:288.99600
UNII:B53E3NMY5C
DSSTox ID:DTXSID9046990
NCI Thesaurus Code:C47760
HScode:2934300000
Categories:
Characteristics-
PSA:
90.4
XLogP3:2.35520
Appearance:white solid
Melting Point:280 °C
Boiling Point:391.2°C at 760 mmHg
Flash Point:9℃
Water Solubility:H2O: ~29 mg/mL
Storage Conditions:Desiccate at RT
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceutical intermediates
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Location:
Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
14
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Total Annual Revenue:
Less than $1 million
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Total Employees:
Less than 5
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Year of Establishment:
2025
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted
India
Tizanidine HCl
300 MG May 29, 2026
Pakistan
TIZANIDINE HCL
10.00 KG Mar 18, 2024 Post an enquiry for this product
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