High Quality CAS 910463-68-2 Top GLP-1 Loss Weight Peptide Semaglutide Fat Burn Raw Powder Lyophilized 5mg 10mg

Sales manager:Lucy
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Semaglutide is a modified molecule our bodies make,It's a protein made in the intestine and results in a decrease in blood sugars and appetite. A small change in the molecule allows the drug to last weeks in our bodies rather than minutes.

 Slows down how quickly food leaves your stomach, leaving you with a feeling of fullness and satisfaction with smaller meals. Lowers blood sugars, in part by reducing the production of sugar in the liver. Slows Intestinal motility (movement of food from mouth out of the body).

Semaglutide  is the newest GLP-1R agonist and was approved by the FDA as a once-weekly injection for the treatment of T2DM in late 2017. The peptide is chemically similar to liraglutide, with the inclusion of two structural modifications (Lau, Bloch, et al., 2015). The first is the replacement of Gly with the non-proteinogenic amino acid 2-aminoisobutyric acid (Aib) at position 2. The second is the attachment of octadecanoic diacid to the side chain of Lys-26 through a short polyethylene glycol (PEG) spacer and a γ-glutamic acid linker. The amino acid substitution renders the peptide more resistant to DPP-4 compared to liraglutide, and the presence of the 18-carbon fatty acid moiety results in a high binding affinity for serum albumin, which translates to a half-life of approximately 7 days in humans.  It is used to treat type 2 diabetes and manage chronic weight. The drug functions similar to human glucagon-like peptide-1 (GLP-1) by increasing secretion, which leads to improved sugar metabolism. It is distributed as a metered subcutaneous injection in a prefilled pen, or as an oral form. One of its advantages over other antidiabetic drugs is that it has a long duration of action, thus, only once-a-week injection is sufficient.

•  Semaglutide is a polypeptide that contains a linear sequence of 31 amino acids joined together by peptide linkages. It is an agonist of glucagon-like peptide-1 receptors (GLP-1 AR) and used for the treatment of type 2 diabetes. It has a role as a hypoglycemic agent, a glucagon-like peptide-1 receptor agonist, an anti-obesity agent, a neuroprotective agent and an appetite depressant. It is a polypeptide and a lipopeptide.
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• Application:1.Semaglutide   powder is applied in the field of dietary health food.2. Semaglutide  powder applied in the field of medicine .
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Peptide Storage Guidelines: General Tips

When storing peptides, remember to:
• Store peptide in a cold, dry, dark place
• Avoid repeated freezing and thawing of peptide
• Avoid overexposure to the air
• Avoid light exposure
• Avoid storing peptides in solution long term
• Aliquot peptide according to experimental requirements

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