Linaclotide, Linaclotide API, Linaclotide Acetate, Linzess, L-Tyrosine, Peptide, Peptide API
GMP COA 4 Inquiries
851199-59-2
Pharmaceutical Grade
99%
Chengdu
Chengdu Shengnuo, Shengnuo Biopharm
g
2025-11-15
Semaglutide API,Tirzepatide API,Liraglutide API,Linaclotide API,Creatine Monohydrate,Copper Tripeptide-1
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Product Description
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Seller Information
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History Price
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Inquiry History
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DescriptionECHEMI Editorial ReferenceLinaclotide is a potent and selective guanylate cyclase C agonist; developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation.
Linaclotide is a fourteen-membered heterodetic cyclic peptide consisting of Cys, Cys, Glu, Tyr, Cys, Cys, Asn, Pro, Ala, Cys, Thr, Gly, Cys and Tyr residues joined in sequence and cyclised by three disulfide bonds: between Cys(1) and Cys(6), between Cys(2) and Cys(10), and between Cys(5) and Cys(13). Used for treatment of irritable bowel syndrome accompanied by constipation. It has a role as a guanylate cyclase 2C agonist.|Linaclotide is an orally administered, peptide agonist of guanylate cyclase 2C for the treatment of irritable bowel syndrome. Chemically, it is a heterodetic cyclic peptide and consists of fourteen amino acids. The protein sequence is as follows: Cys Cys Glu Tyr Cys Cys Asn Pro Ala Cys Thr Gly Cys Tyr. There are three disulfide bonds which are located between Cys1 and Cys6; between Cys2 and Cys10; and between Cys5 and Cys13. FDA approved on August 30, 2012.|Linaclotide is small peptide agonist of guanylate cyclase C receptors in the intestine and is used orally as treatment of chronic constipation and irritable bowel syndrome. Linaclotide has not been linked to serum enzyme elevations during treatment or to episodes of clinically apparent liver injury.Research & Reference NoteLinaclotide, Linaclotide API, Linaclotide Acetate, Linzess, L-Tyrosine, Peptide, Peptide API is listed on ECHEMI for industrial / laboratory sourcing. This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
Authoritative sourcesDisclaimer: This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
Reviewed by ECHEMI Scientific Review - Platform editorial review for research chemicals
CertificatesBasic Info-
Product Name:
Linaclotide
Other Name:Linaclotide;Linaelotide Acetate;Linaelotide
CAS No.:851199-59-2
Molecular Formula:C59H79N15O21S6
InChIKeys:KXGCNMMJRFDFNR-WDRJZQOASA-N
Molecular Weight:1526.73646
Exact Mass:1525.389893
DSSTox ID:DTXSID90234256
Color/Form:White to off-white powder
ATC Code:A06AX04|A - Alimentary tract and metabolism
Categories:
Characteristics-
PSA:
725.71000
XLogP3:-5.84
Density:1.6±0.1 g/cm3
Boiling Point:2045.0±65.0 °C at 760 mmHg
Flash Point:1190.5±34.3 °C
Refractive Index:1.712
Water Solubility:Slightly soluble|Slightly soluble in water|Slightly soluble in aqueous sodium chloride
Storage Conditions:Store at 25 °C (77 °F); excursions permitted between 15 °C and 30 °C (59 °F and 86 °F).
Experimental Properties:Amorphous|14-amino acid peptide
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Semaglutide API,Tirzepatide API,Liraglutide API,Linaclotide API,Creatine Monohydrate,Copper Tripeptide-1
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Location:
Chengdu Shengnuo Biopharm Co., Ltd.
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Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
365
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Total Annual Revenue:
Above $100 million
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Total Employees:
Above 1000
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Year of Establishment:
2004
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Weekly Price
The chart shows the price trend of the product in the past 12 months.
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Inquiry History4 Inquiries
Country Product Purchase Quantity Date Posted
Australia
Linaclotide
1 G Jan 28, 2026
Pakistan
linaclotide
5 KG Dec 23, 2025
China
Linaclotide and Tirzepatide
1000 MT Oct 30, 2025
United States
Linaclotide and other peptides
1 KG Dec 24, 2025 Post an enquiry for this product