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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > GS-441524 for Sale > GS-441524 1191237-69-0 high purity
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GS-441524 1191237-69-0 high purity

ISO 53 Inquiries

Unit Price: Get Latest Price
CAS No.:

1191237-69-0

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

Zentrachem

Packaging:

25kgs in drum

Price valid (until):

2025-12-04

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,D/P,L/C,D/A,100% TT in advance
Average Lead Time:
14 days
Qualification:
Main Products:

pharmaceutical intermediates,excipients,plant extracts,food additives,CDMO,fine cheimcals

  • Product Details

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Shop 1-Methyl-4-pyrazole boronic acid pinacol ester CAS 761446-44-0 pharmaceutical intermediate-Detailed Image 1

    Melting point  > 233° C (dec.)
    density  1.84±0.1 g/cm3(Predicted)
    storage temp.  -20°C


    pka 12.13±0.70(Predicted)
    form  solid
    color  Off-white


     Capability 


     we are capable of:


    1) quick quotation, normally within 1-2 days

    2) full marketing research

    3) price control and quality(regulatory) control

    4) all stage support from sample, pilot, registration and commercial

    5) sourcing for prodcut which is very new or hard to find

    6) CMO/CDMO, from pilot-scale development to industrial-scale manufacturing


      Q&A  


    What are the MOQ and lead time?


    MOQ varies (high-value chemicals may negotiate to g-kg-level).

    Lead time typically 2-4 weeks, with expedited options upon request.


    How do we ensure product quality and compliance?


    We enforce a 3-step protocol:

    ① Source only from ISO-certified suppliers;

    ② Provide batch-specific COA/COO;

    ③ Dedicated team monitors global regulations (e.g., China NECIC, EU SCIP).


    Do we offer customized synthesis?


    Yes!

    We provide end-to-end solutions from R&D to scale-up production.

    Technical specs (e.g., purity, CAS#) and intended use documentation are required.


    How do we handle logistics and customs?


    We support CIF/FOB/DDP/DAP terms, partner with global logistics providers,

    and have in-house experts for HS code classification, hazardous material documentation, etc.


    How do we manage raw material price fluctuations?


    We mitigate risks via long-term contracts, multi-region sourcing,

    and futures hedging, supplemented with quarterly market analysis reports.


      About Us 


    Zentra Chemical, headquartered in Hangzhou, China, is aiming to be a global player in chemical trading and integrated solutions.

    Specializing in Pharmaceutical intermediates, Agrochemical intermediates, Fine chemicals, Herbal extracts and Cosmetic ingredients, we deliver end-to-end services spanning sourcing, supply chain optimization, customized synthesis, cost management, and quality assurance, with all stage support from sample, pilot, registration and commercial

    Our mission is to empower clients worldwide with agile, sustainable, and value-driven partnerships in the ever-evolving chemical industry.

    Competitive Advantages

    • Strategic Location: Based in Hangzhou at the heart of Yangtze River Delta economic zone with global reach
    • Expert Team: International team of chemical engineers, trading specialists and supply chain professionals
    • Quality Commitment: Rigorous supplier selection and ISO-certified quality management systems
    • Sustainable Development: Partnering with eco-friendly manufacturers to promote green chemistry

    Vision & Mission
    Driven by the philosophy of “Chemistry Connects the Future,” Zentra Chemical strives to be a pioneering force in the global chemical sector. By bridging innovation, efficiency, and sustainability, we aim to build long-term partnerships that redefine industry standards and foster a greener, smarter chemical ecosystem.

    Global Reach, Local Expertise – Zentra Chemical is your trusted partner for chemical excellence.


      Why us


    • Supplier, distributor & marketer of chemicals with >20 yrs of experience, with Integrated sourcing solutions
    • Wide product range, We can source any fine chemical you require, unlimited range, including intermediates and products for agrochemicals, cosmetics, APIs, nanotechnology, additives, flavors, fragrances, photography, plant extracts, electronics industries and more
    • We can solve your sourcing problems through our own or third party manufacturing in the most transparent way
    • We supply all stage support from sample, pilot, registration and commercial
    • Through selected pre-qualified partners under exclusive arrangements, we offer Contract manufacturing and custom synthesis, Kilo to Multi-ton scale production
    Shop 3-Fluorocinnamicacid 458-46-8-Detailed Image 1
    Shop 3-Fluorocinnamicacid 458-46-8-Detailed Image 2
    Shop 3-Fluorocinnamicacid 458-46-8-Detailed Image 3
    Shop 3-Fluorocinnamicacid 458-46-8-Detailed Image 4
    Shop 3-Fluorocinnamicacid 458-46-8-Detailed Image 5
    Shop 3-Fluorocinnamicacid 458-46-8-Detailed Image 6
    Shop 3-Fluorocinnamicacid 458-46-8-Detailed Image 7

    Shop 1-Methyl-4-pyrazole boronic acid pinacol ester CAS 761446-44-0 pharmaceutical intermediate-Detailed Image 9

    Shop 1-Methyl-4-pyrazole boronic acid pinacol ester CAS 761446-44-0 pharmaceutical intermediate-Detailed Image 10


      Excipients 


    L-Malic Acid, CAS 97-67-6
    DL-Malic Acid, CAS 617-48-1
    L(+)-Tartaric Acid, CAS 87-69-4
    DL-Tartaric Acid, CAS 133-37-9
    Potassium Bitartrate, CAS 868-14-4
    Aspartame, CAS 22839-47-0
    ISO, Halal, kosher certificates are all available.
    ECHEMI Editorial Reference
    GS-441524 is a nucleoside analogue that terminates the RNA chain of viral RNA-dependent RNA polymerase. GS-441524 was developed by Gilead Sciences, Inc as part of their research into human RNA virus disease such as Ebola. GS-441524 is a small molecule that exhibits potent antiviral activity against a number of RNA viruses, including the zoonotic severe acute respiratory syndrome (SARS) coronavirus ( Cho et al., 2012).
    GS-441524 is a C-nucleoside analog that is (2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile substituted by a 4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl group at position 2. It is the active metabolite of remdesivir and exhibits a broad range of inhibitory activity against various RNA viruses including HCV, parainfluenza and SARS-CoV. It has a role as a drug metabolite, an antiviral agent and an anticoronaviral agent. It is a pyrrolotriazine, a nitrile, a C-nucleoside and an aromatic amine.|GS-441524 is an adenosine nucleotide analog antiviral, similar to [remdesivir]. This molecule was patented in 2009. In vitro studies of GS-441524 have determined it has a higher EC50 than remdesivir against a number of viruses, meaning GS-441524 is less potent. GS-441524 continues to be studied in the treatment of Feline Infectious Peritonitis Virus, a coronavirus that only infects cats.

    Certificates

    Basic Info
    Product Name:

    GS-441524

    Other Name:

    (2R,3R,4S,5R)-2-(4-Aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydro-2-furancarbonitrile;GS-441524;GS441524;(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile;GS-441524 solution;EVO984;EVO 984;EVO-984;GS 441524

    CAS No.:

    1191237-69-0

    Molecular Formula:

    C12H13N5O4

    InChIKeys:

    BRDWIEOJOWJCLU-LTGWCKQJSA-N

    Molecular Weight:

    291.26

    Exact Mass:

    291.096754

    UNII:

    1BQK176DT6

    Characteristics
    PSA:

    150

    XLogP3:

    -1.27552

    Density:

    1.84±0.1 g/cm3(Predicted)

  • Seller Information
    Business Type:

    Trader

    Main Products:

    pharmaceutical intermediates,excipients,plant extracts,food additives,CDMO,fine cheimcals

    Location:

    Rm 301, Bld 2, Taohuahu Neighborhood Center, Hangzhou, China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,100% TT in advance

    Average lead Time:

    14 days

    Total Employees:

    5-10

    Year of Establishment:

    2025

    Zentra Chemical, headquartered in Hangzhou, China, is aiming to be a global leader in chemical trading and integrated solutions.

    Specializing in Pharmaceutical intermediates, Agrochemical intermediates, Fine chemicals, and Cosmetic ingredients, we deliver end-to-end services spanning sourcing, supply chain optimization, customized synthesis, cost management, and quality assurance.

    Our mission is to empower clients worldwide with agile, sustainable, and value-driven partnerships in the ever-evolving chemical industry.


      Why us  


    Supplier, distributor & marketer of chemicals with >20 yrs of experience, with  Integrated sourcing solutions.

    Wide product range , We can source any fine chemical you require, unlimited range, including intermediates and products for agrochemicals, cosmetics, APIs, nanotechnology, additives, flavors, fragrances, photography, plant extracts, electronics industries and more.

    We can solve your sourcing problems through our own or third party manufacturing in the  most transparent way.

    We supply  all stage support from sample, pilot, registration and commercial.

    Through selected  pre-qualified partners  under exclusive arrangements, we offer  Contract manufacturing and custom synthesis , Kilo to Multi-ton scale production.


      Capability  


    with hundreds of local manufacturers(pre-qualified), we are capable of:

    1) quick quotation, normally within 1-2 days;
    2) full marketing research;
    3) price control and quality(regulatory) control;
    4) all stage support from sample, pilot, registration and commercial;
    5) sourcing for prodcut which is very new or hard to find;
    6) CMO/CDMO, from pilot-scale development to industrial-scale manufacturing.

  • Inquiry History
    53 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    GS-441524

    5 MT Oct 23, 2026
    Poland

    GS-441524

    200 G Oct 7, 2026
    Chile

    GS-441524

    100 MT Oct 5, 2026
    Japan

    GS-441524

    100 MT Oct 2, 2026
    Denmark

    GS-441524

    10 PCS Sep 30, 2026
    Italy

    Gs-441524

    20 MG Sep 28, 2026
    United States

    GS-441524

    25 G Sep 22, 2026
    United States

    GS 441524

    30 MG Aug 3, 2026
    United States

    GS-441524

    100 MT Jul 9, 2026
    Mexico

    Fip Cat Gs-441524 Fipv

    1 KG Jul 3, 2026
    Malaysia

    Gs-441524

    10 MG Jun 15, 2026
    China

    GS-441524

    1680 MG May 2, 2026
    Poland

    GS441524 powder

    200 G Mar 11, 2026
    Poland

    GS-441524

    100 G Feb 25, 2026
    Poland

    GS-441524

    1 KG Feb 25, 2026
    Turkey

    gs-441524

    100 G Feb 20, 2026
    United States

    gs441524

    100  Feb 10, 2026
    South Korea

    GS-441524 20mg tablets

    3 PCS Feb 5, 2026
    Bangladesh

    Gs-441524 fipv

    1 MT Jan 26, 2026
    Thailand

    gs-441524

    4 G Jan 16, 2026
    Post an enquiry for this product

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