Isosorbide 5-mononitrate 16051-77-7
2 Inquiries
16051-77-7
Food grade
99%
shenzhen
Flying
10g/1kg/ 10kg/ 25kg
Yes
2025-12-07
vitamin
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Product Details
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial Referencewhite to light yellow crystal powdeIsosorbide 5-mononitrate is a crystalline solid. Isosorbide 5-mononitrate is very flammable and may be toxic by ingestion.
Isosorbide-5-mononitrate is a crystalline solid. It is very flammable and may be toxic by ingestion.|Solid
Isosorbide-5-mononitrate is a crystalline solid. It is very flammable and may be toxic by ingestion.|Isosorbide mononitrate is a nitrate ester and a glucitol derivative. It has a role as a nitric oxide donor and a vasodilator agent.|Isosorbide mononitrate is an organic nitrate with vasodilating properties. It is an anti-anginal agent that works by relaxing the smooth muscles of both arteries and veins, but but predominantly veins to reduce cardiac preload. Isosorbide mononitrate is an active metabolite of [isosorbide dinitrate]. Like other organic nitrates, isosorbide mononitrate acts as a prodrug for its active metabolite, [nitric oxide], which mediates the therapeutic action of isosorbide mononitrate. Isosorbide mononitrate has a longer duration of action than [nitroglycerin] due to its slow onset of absorption and metabolism. First approved by the FDA in 1991, isosorbide mononitrate is used for the prevention and management of angina pectoris caused by coronary artery disease; however, the onset of action of orally-administered isosorbide mononitrate is not rapid enough to offset an acute anginal episode. It is available in oral tablets generically and under the brand name ISMO and Monoket. The extended-release forms of the drug are also available generically and under the brand name Imdur.|Isosorbide mononitrate is a Nitrate Vasodilator. The physiologic effect of isosorbide mononitrate is by means of Vasodilation.|Isosorbide Mononitrate is the mononitrate salt form of isosorbide, an organic nitrate with vasodilator activity. Isosorbide mononitrate relaxes vascular smooth muscle by formation of the free radical nitric oxide (NO), which is identical to the endothelium-derived relaxing factor (EDRF). NO activates guanylyl cyclase, thereby increasing the synthesis of cGMP within smooth muscle, resulting in dephosphorylation of light chain myosin and relaxation of peripheral arteries and veins. In addition, isosorbide mononitrate relaxes coronary arteries, thereby increasing the blood circulation through the ischemic area. (NCI05)
white to light yellow crystal powde
ChEBI: Isosorbide mononitrate is a nitrate ester and a glucitol derivative. It has a role as a nitric oxide donor and a vasodilator agent.Basic Info-
Product Name:
Isosorbide 5-mononitrate
Other Name:IMDUR;IS-5-MN;ISOSORBIDE 5-MONONITRATE;ISOSORBIDE 5-NITRATE;ELANTAN;ELAN;CORANGIN;5-ISOSORBIDE MONONITRATE
CAS No.:16051-77-7
Molecular Formula:C6H9NO6
InChIKeys:YWXYYJSYQOXTPL-SLPGGIOYSA-N
Molecular Weight:191.14
Exact Mass:191.14
EC Number:240-197-2
UNII:LX1OH63030
NSC Number:758619
UN Number:3251
DSSTox ID:DTXSID9023176
NCI Thesaurus Code:C47575
Color/Form:White to Off-White
ATC Code:C - Cardiovascular system
HScode:2932999000
Categories:
Characteristics-
PSA:
93.7
XLogP3:-0.9
Density:1.5784 (rough estimate)
Melting Point:88-93 °C
Boiling Point:326.86°C (rough estimate)
Flash Point:174.2±27.9 °C
Refractive Index:145 ° (C=5, H2O)
Water Solubility:soluble
Storage Conditions:-20°C Freezer
Toxicity:LD50 oral in rat: 2010mg/kg
Specific rotation:170 º (c=1, EtOH)
PKA:13.09±0.40(Predicted)
Air and Water Reactions:Highly flammable.
Reactive Group:Alcohols and Polyols
Reactivity Alerts:Highly Flammable
Reactivity Profile:The dinitrate, a heart drug, can detonate when dry, but is non explosive with 30% of water [J. Haz.. Mater., 1992, 32(1), 87]. The mononitrate would be expected to be less reactive.
Critical Temperature & Pressure:-20°C Freezer
Hazard IdentificationClassification of the substance or mixture
Flammable solids, Category 2
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H228 Flammable solid
H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P203 Obtain, read and follow all safety instructions before use.
Response P370+P378 In case of fire: Use ... to extinguish.
P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
vitamin
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Location:
Room 2-502, Building 6, Luneng Tehran Garden Building, No.8 Changbin Road, Xiuying district, Haikou City, Hainan Province
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Payment Terms:
TT against copy of documents,TT against B/L draft before shipment
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Average lead Time:
25 days
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
Less than 5
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Year of Establishment:
2023
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted
Pakistan
Isosorbide Mononitrate
400 KG Aug 12, 2025
Pakistan
Isosorbide 5-mononitrate
200 KG Mar 31, 2026 Post an enquiry for this product
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