Product Name: 3-Cyano-2-hydroxyphenylboronic acid pinacol ester
CAS No.: 2361216-95-5
Molecular Formula: C₁₃H₁₆BNO₃
Purity: ≥97% (HPLC)
Appearance: White to off-white crystalline powder

Product Overview

3-Cyano-2-hydroxyphenylboronic acid pinacol ester (CAS 2361216-95-5) is a high-purity, multifunctional boron-containing intermediate of exceptional value in modern pharmaceutical research and development. Its unique structure, incorporating a protected boronic ester, a phenolic hydroxyl group, and a nitrile function, makes it a versatile and critical building block for constructing complex bioactive molecules, particularly in the field of targeted cancer therapies.

Key Features & Advantages:

• High Purity & Quality: We guarantee a consistent purity of ≥97%, ensuring reliable performance and high yields in critical coupling reactions.

• Versatile Synthetic Handle: The pinacol-protected boronic ester is highly stable and readily participates in Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern medicinal chemistry for building biaryl structures.

• Multifunctional Reactivity: The presence of adjacent cyano and phenolic hydroxyl groups provides additional sites for chemical modification, enabling the synthesis of diverse and complex molecular architectures.

• Critical for Drug Discovery: This intermediate is specifically designed for the synthesis of innovative kinase inhibitors and other targeted small molecule therapeutics.

• Strict Quality Control: Every batch is rigorously characterized and supported by comprehensive analytical data (including HPLC and NMR) to meet the stringent requirements of pharmaceutical R&D.

Primary Applications:

• Pharmaceutical Intermediate: A key building block in the research and development of Active Pharmaceutical Ingredients (APIs), especially for tyrosine kinase inhibitors and other targeted anti-cancer drugs.

• Organic Synthesis: An essential reagent in metal-catalyzed cross-coupling reactions to create novel biaryl compounds for agrochemicals and material science.

• R&D Building Block: Used in medicinal chemistry for the exploration of new chemical entities with potential biological activity.

Packaging & Storage:

• Packaging: Available from grams to kilograms. Custom packaging is available upon request to suit your R&D or production scale.

• Storage: Store in a cool, dry, and well-ventilated place. Keep container tightly closed under an inert atmosphere (e.g., N₂) to ensure long-term stability. Moisture-sensitive.

Why Choose Our Product?

We specialize in providing high-value, complex boronic esters and other advanced intermediates for the pharmaceutical industry. We are committed to delivering not only superior product quality but also exceptional technical support. Our competitive pricing and reliable supply chain make us your ideal partner for both research and scale-up projects.

Contact us today to request a quotation, a sample, or a detailed technical data sheet!