Gefapixant Base & Citrate

Beijing Ruqueen Biotech.， Co., Ltd.  is a high-tech enterprise integrating the R&D and business promotion of novel food ingredients,  API s and intermediates, and novel pharmaceutical excipients. The company advocates a green, eco-friendly, and differentiated approach to health and wellness, emphasizing RSM ( Regulatory Starting Material )   research and QbD (Quality by Design) process development to ensure economical, environmentally friendly, safe, and quality-controllable manufacturing processes.

The company operates a  1,000+ square meter R&D center  in the Beijing Economic-Technological Development Area (BDA), housing departments for process development, pilot-scale conversion, commercial production, quality research, and business promotion.

The center's team comprises  Ph.D. and M.S. holders in chemistry  with over 20 years of commercial production experience in APIs. It is equipped with multiple advanced instruments including:   50/100L glass reactors , 20L rotary evaporators , HPLC , IR , LC-MS , GC-MS . Additionally ,  the company maintains  stable cooperative manufacturing bases  in Tianjin  City , Hebei  Province , Shandong  Province , Inner Mongolia Autonomous Region, and other regions, enabling scaled commercial production.

The company conducts R&D and commercial manufacturing of:   Complex active pharmaceutical ingredients (APIs) , Pharmaceutical intermediates , Novel food ingredients  and Advanced pharmaceutical excipients

The company provides comprehensive services including:
✓ Registration filing support for APIs/excipients (e.g., DMF/CEP preparation)
✓ Process optimization for existing pharmaceutical materials
✓ Enabling "API + Formulation" integration strategies for pharmaceutical partners

Intellectual Property Achievements:
✓ 3 authorized invention patents
✓ 8 pending patent applications (including 2 PCT international filings)