 Home > Pharmaceutical Intermediates > Metabolic Bone Disease > Butanedioic acid 4-amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide for Sale > Prucalopride Succinate API - A Selective 5-HT4 Agonist for Chronic Constipation.

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Prucalopride Succinate API - A Selective 5-HT4 Agonist for Chronic Constipation.

Name: Prucalopride Succinate API - A Selective 5-HT4 Agonist for Chronic Constipation.
Brand: Tianrui
SKU: pr2511121369
Price: 11 USD
Availability: InStock

1 Inquiries

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CAS No.:

179474-85-2

Grade:

Pharmaceutical Grade

Content:

98.5%

Port:

Qingdao

Brand:

Tianrui

Packaging:

Sealed fiber drum

Price valid (until):

2025-11-12

Contact Supplier

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Hefei Tianrui Pharmaceutical Chemical Co., Ltd.

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

APIs

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Product Description
Seller Information
Inquiry History

Description

About Product

Prucalopride Succinate (CAS: 179474-81-8) is a high-purity, chiral active pharmaceutical ingredient (API) that functions as a selective 5-HT4 receptor agonist. Specifically developed for the treatment of chronic idiopathic constipation, it enhances gastrointestinal motility with proven efficacy. Manufactured by Hefei TianRui Pharmaceutical under strict cGMP conditions, our Prucalopride Succinate API guarantees high chiral purity, excellent stability, and reliable quality for gastrointestinal drug formulations.

Items	Specifications
Product Name	Prucalopride Succinate
CAS Registry Number	179474-81-
IUPAC Name	4-Amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydrobenzofuran-7-carboxamide succinate
Molecular Weight	485.93 g/mol
Solubility	It is soluble in water, soluble in methanol, and slightly soluble in ethanol.
Melting Point	160-163°C
Primary Use	Chronic idiopathic constipation Gastrointestinal motility disorder

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Company Profile

Founded: 2014
Focus: High-tech enterprise specializing in the development and industrialization of small-molecule pharmaceutical synthesis technology
Facilities:
- Two workshops (TR1 & TR2) with total capacity ≈ 1000 tons/year
- Reactors: 3000L×15, 2000L×10, and numerous smaller reactors (1000L, 500L, 100L)
- Ultra-low temperature cryogenic reactor (explosion-proof workshop included)
- GMP workshop & clean room
QC Lab Equipment: GC×2, HPLC×3, UV, IR, KF titrator, etc.

About company

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In 2015, the company developed polypeptide absorbent permeation enhancers: ethyl 8-bromo-octanoate and Carsalam, which is the 1st and only qualified Chinese supplier of Semaglutide to meet the internal control requirements of innovator Novo Nordisk.

In 2020, the company independently developed and optimized 8-bromo-octanoic acid and 6-bromo-caproic acid to become a COVID-19 vaccine carrier manufacturer and supplier to Moderna company, contributing its share to the fight against COVID-19.

In 2022, Tianrui R&D Center and cGMP manufacturing facility was inaugurated and put into operation. And in the same year, polypeptide absorbent permeation enhancers SNAC (Salcaprozate Sodium) has successfully obtained the domestic CDE registration number (F20220000072) and the US FDA registration number (037135), and another batch of innovative APIs and pharmaceutical excipients are under registration and approval.

Basic Info

Product Name:

Butanedioic acid 4-amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide

Other Name:

Butanedioic acid 4-amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide;Prucalopride Succinate;Prucalopride Succinate API;PRUCALOPRIDE INTERMEDIATES;Prucalopride Succinat;Prucalopride Succinate WS;Butanedioic acid, compd. with 4-amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide (1:1);Prucalopride Impurity

CAS No.:

179474-85-2

Molecular Formula:

C18H26ClN3O3.C4H6O4

InChIKeys:

QZRSNVSQLGRAID-UHFFFAOYSA-N

Molecular Weight:

485.95838

Exact Mass:

485.192871

EC Number:

1592732-453-0

UNII:

4V2G75E1CK

ATC Code:

A06AX05

Categories:

Metabolic Bone Disease

Characteristics

PSA:

151

XLogP3:

3.11750

See More Butanedioic acid 4-amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H412 Harmful to aquatic life with long lasting effects
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P273 Avoid release to the environment.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Butanedioic acid 4-amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
APIs

Location:
No.23,lntersection of Fenglehe Avenue and Leiyang Road, Huagang Town,Feixi County, Hefei, Anhui, China.

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15

Total Annual Revenue:
$50 million-$100 million

Total Employees:
11-50

Year of Establishment:
2014

About TianRui

Hefei TianRui Pharmaceutical Chemical Co., Ltd was founded in 2014 as a high-tech enterprise focused on the development and industrialization of pharmaceutical small molecule synthesis technology. Our workshop and R&D center are located in Hefei HuaGang Provincial Industrial Park, Anhui Province. We are committed to providing professional technical services and commercialization of small molecule specialty APIs, CGMP standard intermediates, and functional pharmaceutical excipients and MRNA vaccine vectors for domestic and overseas well-known pharmaceutical companies.

Main Events

In 2015, the company developed polypeptide absorbent permeation enhancers: ethyl 8-bromo-octanoate and Carsalam, which is the 1st and only qualified Chinese supplier of Semaglutide to meet the internal control requirements of innovator Novo Nordisk.

In 2020, the company independently developed and optimized 8-bromo-octanoic acid and 6-bromo-caproic acid to become a COVID-19 vaccine carrier manufacturer and supplier to Moderna company, contributing its share to the fight against COVID-19.

In 2022, Tianrui R&D Center and cGMP manufacturing facility was inaugurated and put into operation. And in the same year, polypeptide absorbent permeation enhancers SNAC (Salcaprozate Sodium) has successfully obtained the domestic CDE registration number (F20220000072) and the US FDA registration number (037135), and another batch of innovative APIs and pharmaceutical excipients are under registration and approval.

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Prucalopride succinate	100 KG	May 8, 2025

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