Cinacalcet CAS: 226256-56-0
GMP ISO
226256-56-0
Pharmaceutical Grade
99%
Shenzhen
25kg 100kg 1000kg
Yes
2025-12-13
Pharmaceutical intermediate/API， and fragrances API
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Product Details
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Seller Information
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DescriptionECHEMI Editorial ReferenceCinacalcet is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease treatment.
Solid
Cinacalcet is a secondary amino compound that is (1R)-1-(naphthalen-1-yl)ethanamine in which one of the hydrogens attached to the nitrogen is substituted by a 3-[3-(trifluoromethyl)phenyl]propyl group. It has a role as a calcimimetic and a P450 inhibitor. It is a member of naphthalenes, a secondary amino compound and a member of (trifluoromethyl)benzenes.|Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe. It is used to treat hyperparathyroidism due to parathyroid tumours or renal failure.|Cinacalcet is a Calcium-sensing Receptor Agonist. The mechanism of action of cinacalcet is as an Increased Calcium-sensing Receptor Sensitivity.CertificatesBasic Info-
Product Name:
Cinacalcet
Other Name:1-Naphthalenemethanamine,α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-,(αR)-;(αR)-α-Methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine;Cinacalcet;AMG 073;N-[(1R)-1-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine;Parareg
CAS No.:226256-56-0
Molecular Formula:C22H22F3N
InChIKeys:InChIKey=VDHAWDNDOKGFTD-MRXNPFEDSA-N
Molecular Weight:357.41
Exact Mass:357.41
EC Number:1308068-626-2
UNII:UAZ6V7728S
DSSTox ID:DTXSID8048286
ATC Code:H05BX01|H - Systemic hormonal preparations, excl. sex hormones and insulins
HScode:2921499090
Categories:
Characteristics-
PSA:
12
XLogP3:6.1
Density:1.2±0.1 g/cm3
Flash Point:220.5±28.7 °C
Refractive Index:1.563
Water Solubility:Slightly soluble (in HCl salt form)
Storage Conditions:Refrigerator
Vapor Pressure:1.5X10-7 mm Hg at 25 deg C at 25 deg C /Estimated/
Henrys Law Constant:Henry's Law constant = 2.2X10-7 atm-cu m/mole at 25 °C /Estimated/
Dissociation Constants:pKa = 8.4 /Estimated/
Experimental Properties:White to off white crystalline solid. Soluble in methanol. Soluble in 95% ethanol. Slightly soluble in water. /Hydrochloride/|Hydroxyl radical reaction rate constant = 8.3X10-11 cu cm/molec-sec at 25 °C /Estimated/
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Skin irritation, Category 2
Eye irritation, Category 2
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P203 Obtain, read and follow all safety instructions before use.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceutical intermediate/API， and fragrances API
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Location:
Building B, Sniff Titanium Workshop, No. 26 Shucheng Road, Hongshan District，Wuhan
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Payment Terms:
100% TT in advance
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Total Annual Revenue:
$1 million-$2.5 million
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Total Employees:
5-10
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Year of Establishment:
2020
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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