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Conivaptan Hydrochloride API - A Dual Vasopressin Receptor Antagonist for Hyponatremia.

Name: Conivaptan Hydrochloride API - A Dual Vasopressin Receptor Antagonist for Hyponatremia.
Brand: Tianrui
SKU: pr2511131356
Price: 11 USD
Availability: InStock

Unit Price: Get Latest Price 

CAS No.:

168626-94-6

Grade:

Pharmaceutical Grade

Content:

98.5%

Port:

Qingdao

Brand:

Tianrui

Packaging:

Sealed fiber drum

Price valid (until):

2025-11-12

Contact Supplier

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Hefei Tianrui Pharmaceutical Chemical Co., Ltd.

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

APIs

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Product Description
Seller Information

Description

About Product

Garenoxacin (CAS: 194804-75-6) is a high-purity active pharmaceutical ingredient (API) belonging to the novel des-fluoro quinolone class of antibiotics. It demonstrates broad-spectrum activity against Gram-positive and Gram-negative bacteria, particularly effective in treating respiratory tract infections and complicated urinary tract infections. Manufactured by Hefei TianRui Pharmaceutical under strict cGMP conditions, our Garenoxacin API guarantees high purity, excellent stability, and reliable quality for anti-infective formulations.

Items	Specifications
Product Name	Conivaptan Hydrochloride
CAS Registry Number	210101-16-9
IUPAC Name	(2R,4S)-5-(5'-fluoro-2'-methoxy-[1,1'-biphenyl]-4-carbonyl)-2-methyl-1-[2-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]piperidine-4-carboxamide monohydrochloride
Molecular Weight	608.10 g/mol
Solubility	Dissolves in methanol, slightly soluble in ethanol, and extremely insoluble in water.
Primary Use	Isotonic hyponatremia Syndrome of Antidiuretic Hormone Secretion Abnormality (SIADH)

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Company Profile

Founded: 2014
Focus: High-tech enterprise specializing in the development and industrialization of small-molecule pharmaceutical synthesis technology
Facilities:
- Two workshops (TR1 & TR2) with total capacity ≈ 1000 tons/year
- Reactors: 3000L×15, 2000L×10, and numerous smaller reactors (1000L, 500L, 100L)
- Ultra-low temperature cryogenic reactor (explosion-proof workshop included)
- GMP workshop & clean room
QC Lab Equipment: GC×2, HPLC×3, UV, IR, KF titrator, etc.

About company

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In 2015, the company developed polypeptide absorbent permeation enhancers: ethyl 8-bromo-octanoate and Carsalam, which is the 1st and only qualified Chinese supplier of Semaglutide to meet the internal control requirements of innovator Novo Nordisk.

In 2020, the company independently developed and optimized 8-bromo-octanoic acid and 6-bromo-caproic acid to become a COVID-19 vaccine carrier manufacturer and supplier to Moderna company, contributing its share to the fight against COVID-19.

In 2022, Tianrui R&D Center and cGMP manufacturing facility was inaugurated and put into operation. And in the same year, polypeptide absorbent permeation enhancers SNAC (Salcaprozate Sodium) has successfully obtained the domestic CDE registration number (F20220000072) and the US FDA registration number (037135), and another batch of innovative APIs and pharmaceutical excipients are under registration and approval.

Basic Info

Product Name:

Conivaptan hydrochloride

Other Name:

[1,1′-Biphenyl]-2-carboxamide,N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-,hydrochloride (1:1);[1,1′-Biphenyl]-2-carboxamide,N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-,monohydrochloride;YM 087;Conivaptan hydrochloride;Vaprisol;conivaptan monohydrochloride

CAS No.:

168626-94-6

Molecular Formula:

C32H26N4O2.ClH

InChIKeys:

InChIKey=BTYHAFSDANBVMJ-UHFFFAOYSA-N

Molecular Weight:

535.04

Exact Mass:

534.182251

EC Number:

1312995-182-4

UNII:

75L57R6X36

DSSTox ID:

DTXSID70168585

Categories:

Metabolic Bone Disease

Characteristics

PSA:

78.1

XLogP3:

7.44730

Melting Point:

>250 °C

Boiling Point:

751.2°C at 760 mmHg

Flash Point:

408.1ºC

Vapor Pressure:

1.89E-22mmHg at 25°C

See More Conivaptan hydrochloride Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Conivaptan hydrochloride Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
APIs

Location:
No.23,lntersection of Fenglehe Avenue and Leiyang Road, Huagang Town,Feixi County, Hefei, Anhui, China.

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15

Total Annual Revenue:
$50 million-$100 million

Total Employees:
11-50

Year of Establishment:
2014

About TianRui

Hefei TianRui Pharmaceutical Chemical Co., Ltd was founded in 2014 as a high-tech enterprise focused on the development and industrialization of pharmaceutical small molecule synthesis technology. Our workshop and R&D center are located in Hefei HuaGang Provincial Industrial Park, Anhui Province. We are committed to providing professional technical services and commercialization of small molecule specialty APIs, CGMP standard intermediates, and functional pharmaceutical excipients and MRNA vaccine vectors for domestic and overseas well-known pharmaceutical companies.

Main Events

In 2015, the company developed polypeptide absorbent permeation enhancers: ethyl 8-bromo-octanoate and Carsalam, which is the 1st and only qualified Chinese supplier of Semaglutide to meet the internal control requirements of innovator Novo Nordisk.

In 2020, the company independently developed and optimized 8-bromo-octanoic acid and 6-bromo-caproic acid to become a COVID-19 vaccine carrier manufacturer and supplier to Moderna company, contributing its share to the fight against COVID-19.

In 2022, Tianrui R&D Center and cGMP manufacturing facility was inaugurated and put into operation. And in the same year, polypeptide absorbent permeation enhancers SNAC (Salcaprozate Sodium) has successfully obtained the domestic CDE registration number (F20220000072) and the US FDA registration number (037135), and another batch of innovative APIs and pharmaceutical excipients are under registration and approval.
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