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Opicapone 923287-50-7

Unit Price: Get Latest Price
CAS No.:

923287-50-7

Grade:

Food grade

Content:

99%

Port:

shenzhen

Brand:

Flying

Packaging:

10g/1kg/ 10kg/ 25kg

Price valid (until):

2025-12-18

Company Type:
Trader
Location:
China
Qualification:
Main Products:

vitamin

  • Product Description

  • Seller Information

  • Description


      Product Detail  


    Superiority

    1.High quality and competitive price.
    2.Free sample for your evaluation.
    3.Promptly delivery by well-reputed shipping lines.
    4.Trial order is available for testing after samples.  
    5.We will inform you all the information at every stage in advance.
    6.Packaging can gear to buyers’ special request. 

    Our service

    1. Reply your inquiry in 24 working hours.
    2. Customized design is available. OEM are welcomed.
    3. Exclusive and unique solution can be provided to our customer by our well-trained and professional engineers and
    staff.
    4. Professional factory: We are manufacturer, specializing in producing all kinds of herb extract for more than 10 years, competitive with good quantity.
    5. As an honest seller, we always use superior raw material, advanced machines, skilled technicians to ensure our products to be finished in high quality and stable feature.


    Hainan Flying International Trade Co., Ltd., was established in 2020, It is a professional supplier of Human APIs, Veterinary, Food Additives, Vitamins, Chemicals, Plant Extract and natural active ingredients. It has absolute advantage because of strong research strength, modern management system and high-quality marketing team.

    For customer’s needs, OEM service is also acceptable. If you have a good idea in new product production but lack of laboratory device and human resource, we are glad to solve this problem for you. Sincerely hope to strengthen exchanges and cooperation with friends from both home and abroad.

    .






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    RAQ





    Q1: How to confirm the Product Quality before placing orders?
    A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirement for confirmation.

    Q2: Can you supply free samples?
    A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

    Q3: How do you treat quality complaints?
    A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. In case any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

    Q4: What's your MOQ ? 
    A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
    Q: Is there a discount ?
    A: Yes, for larger quantity, we always support with better price.

    Q5: How to start orders or make payments ?
    A: You can send our your Purchase order ( if your company has ), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.


    Opicapone is a ring assembly and an oxadiazole.|Opicapone is a potent, reversible, and peripherally-acting third-generation inhibitor of catechol-o-methyltransferase (COMT), an enzyme involved in the breakdown of various catecholamines including dopamine. In June 2016, the European Commission granted a marketing authorization valid throughout the European Union for OPC, indicated as adjunct therapy to levodopa and decarboxylase inhibitors in adult patients with Parkinson's disease and end-of-dose motor fluctuations. In April 2020, the FDA approved the use of opicapone as adjunctive treatment to levodopa/carbidopa in patients with Parkinson’s disease (PD) experiencing “off” episodes. Opicapone is marketed as, under the brand name Ongentys as once-daily oral capsules. Almost all individuals with Parkinson’s disease whom are treated with levodopa plus a dopa decarboxylase (DDC) inhibitor (eg carbidopa) will develop motor complications in time. The initial step in the management is changing the levodopa/DDC inhibitor dosage and the use of adjunct drugs. Various options include supplementing with a dopamine agonist, a monoamine oxidase B inhibitor (selegiline, rasagiline), a catechol-O-methyl transferase (COMT) inhibitor, or amantadine, or using a modified-release formulation of levodopa. The newest adjunctive option is opicapone. This drug is a peripherally selective reversible COMT inhibitor that offers the benefit of a duration of action exceeding 24h, allowing for once-daily administration. Opicapone demonstrates the lowest risk for cytotoxicity in comparison with other catechol-O-methyltransferase inhibitors.|Opicapone is a Catechol-O-Methyltransferase Inhibitor. The mechanism of action of opicapone is as a Catechol O-Methyltransferase Inhibitor.

    Basic Info
    Product Name:

    Opicapone

    Other Name:

    1,2-Benzenediol,5-[3-(2,5-dichloro-4,6-dimethyl-1-oxido-3-pyridinyl)-1,2,4-oxadiazol-5-yl]-3-nitro-;5-[3-(2,5-Dichloro-4,6-dimethyl-1-oxido-3-pyridinyl)-1,2,4-oxadiazol-5-yl]-3-nitro-1,2-benzenediol;Opicapone;BIA 9-1067;5-[3-(2,5-Dichloro-4,6-dimethyl-1-oxy-pyridin-3-yl)-[1,2,4]oxadiazol-5-yl]-3-nitrobenzene-1,2-diol;Ongentys;2,5-Dichloro-3-(5-(3,4-dihydroxy-5-nitrophenyl)-1,2,4-oxadiazol-3-yl)-4,6-dimethylpyridine 1-oxide;1206590-61-5

    CAS No.:

    923287-50-7

    Molecular Formula:

    C15H10Cl2N4O6

    InChIKeys:

    InChIKey=ASOADIZOVZTJSR-UHFFFAOYSA-N

    Molecular Weight:

    413.16900

    Exact Mass:

    413.17

    UNII:

    Y5929UIJ5N

    ATC Code:

    N04|N - Nervous system

    Characteristics
    PSA:

    150.66000

    XLogP3:

    4.59830

    Density:

    1.80±0.1 g/cm3 (20 °C, 760 mmHg)

    Boiling Point:

    701.1±70.0 °C (760 mmHg)

    Water Solubility:

    minimal

  • Seller Information
    Business Type:

    Trader

    Main Products:

    vitamin

    Location:

    Room 2-502, Building 6, Luneng Tehran Garden Building, No.8 Changbin Road, Xiuying district, Haikou City, Hainan Province

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment

    Average lead Time:

    25

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    Less than 5

    Year of Establishment:

    2023

  • Country Product Purchase Quantity Date Posted
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