L-Citrulline RC06284
13 Inquiries
372-75-8
Pharmaceutical Grade
99%
Royalchem
25kg/drum
2030-01-01
Pharmaceutical intermediates
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceL-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.
Solid
L-citrulline is the L-enantiomer of citrulline. It has a role as an EC 1.14.13.39 (nitric oxide synthase) inhibitor, a protective agent, a nutraceutical, a micronutrient, a human metabolite, an Escherichia coli metabolite, a Saccharomyces cerevisiae metabolite and a mouse metabolite. It is an enantiomer of a D-citrulline. It is a tautomer of a L-citrulline zwitterion.|Citrulline is an amino acid. It is made from ornithine and carbamoyl phosphate in one of the central reactions in the urea cycle. It is also produced from arginine as a by-product of the reaction catalyzed by NOS family. Its name is derived from citrullus, the Latin word for watermelon, from which it was first isolated.|Citrulline is a non-essential amino acid. In hepatocytes, L-citrulline is synthesized in the urea cycle by the addition of carbon dioxide and ammonia to ornithine. L-citrulline is converted into L-arginine by the enzymes argininosuccinate synthetase and argininosuccinate lyase in the presence of L-aspartate and ATP. Subsequently, L-arginine is converted to nitric oxide by nitric oxide synthase and L-citrulline is regenerated as a by-product.Basic Info-
Product Name:
Citrulline
Other Name:L-Ornithine,N5-(aminocarbonyl)-;Ornithine,N5-carbamoyl-,L-;N5-(Aminocarbonyl)-L-ornithine;α-Amino-δ-ureidovaleric acid;Nδ-Carbamylornithine;δ-Ureidonorvaline;Citrulline;N5-Carbamoyl-L-ornithine;Cit;L-Citrulline;NSC 27425;L-(+)-Citrulline
CAS No.:372-75-8
Molecular Formula:C6H13N3O3
InChIKeys:InChIKey=RHGKLRLOHDJJDR-BYPYZUCNSA-N
Molecular Weight:175.19
Exact Mass:175.19
BRN:6055157
EC Number:206-759-6
UNII:29VT07BGDA
NCI Thesaurus Code:C53406
HScode:29241900
Categories:
Characteristics-
PSA:
118
XLogP3:-3.19
Appearance:White Crystals or Crystalline Powder
Density:1.3±0.1 g/cm3
Melting Point:235.5 °C
Boiling Point:306.48°C (rough estimate)
Flash Point:187.7±27.9 °C
Refractive Index:1.531
Water Solubility:H2O: 200 g/L (20 ºC)
Storage Conditions:Store at 0-5°C
Specific rotation:25.5 º (c=8, 6N HCl)
PKA:2.43(at 25 °C)
Dissociation Constants:2.43 (at 25 °C)
Collision Cross Section:138 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|139.51 Ų [M-H]- [CCS Type: DT, Method: stepped-field]|132 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine]|137.7 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|139.4 Ų [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|135.4 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|135.5 Ų [M-H]-
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceutical intermediates
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Location:
Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
14 days
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Total Annual Revenue:
Less than $1 million
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Total Employees:
Less than 5
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Year of Establishment:
2025
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Inquiry History13 Inquiries
Country Product Purchase Quantity Date Posted 
United States
L Citrulline
1 MT Jul 31, 2026 
Spain
L –Citrulline DL-Malate (2:1)
1000 KG Jul 14, 2026
United States
L-Citrulline USP
100 KG Jul 28, 2025 
India
L Citrulline Base
100.00 KG Jan 31, 2024 
Israel
L-Citrulline 99.9% HAIDE BIOTECH
200 KG Oct 17, 2023 
Netherlands
L-Citrulline
11 MT Jun 23, 2026 
United Kingdom
L-Citrulline
1000 KG Mar 30, 2026 
Australia
L-Citrulline
130 KG Nov 20, 2024
United States
L-citrulline
50 KG Oct 11, 2024
United States
L-Citrulline
1 20' Fcl May 19, 2026
United States
L-Citrulline
100 KG Mar 27, 2025
Australia
L citruline
50 KG Mar 7, 2024
India
L-Citrulline
100.00 KG Feb 27, 2024 Post an enquiry for this product
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