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Vitamin B12 68-19-9 C63H88CoN14O14P

Name: Vitamin B12 68-19-9 C63H88CoN14O14P
Brand: Orient
SKU: pr2511251302
Price: 1500 USD
Availability: InStock

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Unit Price:

$1500-1600/KG FOB

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CAS No.:

68-19-9

Grade:

Food Grade

Content:

99%

Port:

shanghai

Brand:

Orient

Packaging:

25kg/bag,500kg/bag, customized

Price valid (until):

2026-12-25

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

Vitamin B12 Basic information

outline Chemical properties The structure of vitamin B12 Uses Physiologic function Main Application Content Analysis Toxicity Limited use Production method

Product Name:	Vitamin B12
Synonyms:	hemomin;hepacon-b12;hepagon;hepavis;hepcovite;lactobacilluslactisdornerfactor;lldfactor;macrabin
CAS:	68-19-9
MF:	C63H88CoN14O14P
MW:	1355.37
EINECS:	200-680-0
Product Categories:	Pharmaceutical intermediates;Inhibitors;Vitamin series;Cobalamin, vitamin B-12;vitamin;Mainly used in the treatment of giant young red blood cell anemia, nutritional bad blood loss anemia, neuralgia and obstructive disease;Organometallics;Vitamin Ingredients;Carbohydrates & Derivatives;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Nutritional Supplements;Vitamins and derivatives;Biochemistry;Classes of Metal Compounds;Co (Cobalt) Compounds;Porphyrins;Transition Metal Compounds;Vitamins;68-19-9
Mol File:	68-19-9.mol

Vitamin B12 Chemical Properties

Melting point	>300°C
alpha	23656 -59 ± 9° (dil aq soln)
Boiling point	>300 °C
bulk density	450-600kg/m3
Fp	9℃
storage temp.	2-8°C
solubility	Sparingly soluble in water and in ethanol (96 per cent), practically insoluble in acetone. The anhydrous substance is very hygroscopic.
pka	pKa 3.28±0.04(H2O,D2O t=23±0.5 Iunspeci?ed) (Uncertain)
form	Crystalline Powder or Crystals
color	Red to dark red
Odor	dark red cryst. or powd., odorless and tasteless
PH	6.0 (20°C, 1g/L in H2O)
biological source	synthetic ((organic))
Water Solubility	Soluble
Sensitive	Hygroscopic
Merck	14,10014
BRN	4122889
Exposure limits	NIOSH: IDLH 25 mg/m3
Stability:	Hygroscopic. Keep cold and dry.
InChIKey	RMRCNWBMXRMIRW-WZHZPDAFSA-L
LogP	3.570 (est)
EPA Substance Registry System	Vitamin B12 (68-19-9)

Safety Information

Hazard Codes
HS Code	2936260000
Hazardous Substances Data	68-19-9(Hazardous Substances Data)
Toxicity	LD50 intravenous in mouse: 2gm/kg

Vitamin B12 Usage And Synthesis

outline	Vitamin B12, also known as cobalamin, is a complex organic compound that belongs to the B vitamins. It contains trivalent cobalt in a porphyrin Corrin plane at the center of the ring, making it the largest and most complex vitamin molecule. Vitamin B12 is the only vitamin that contains a metal ion, giving it a red crystal appearance. Plant sources do not contain Vitamin B12, so it cannot be naturally produced by plants. The liver is the best source of Vitamin B12, followed by milk, meat, eggs, and fish. Vitamin B12 plays an essential role as a coenzyme in the synthesis of RNA and DNA. A deficiency of Vitamin B12 can lead to pathological changes in the nervous system, affecting both the peripheral nerves and the central nervous system. The discovery of Vitamin B12 can be attributed to the research conducted in the treatment of pernicious anemia, a previously incurable disease. In 1926, Minot and Murphy found that large amounts of raw liver could cure the disease, for which they were awarded the 1934 Nobel Prize in Physiology and Medicine. This led to the successful treatment of pernicious anemia using liver concentrate. In 1948, Smith and Parker independently isolated a red crystal from liver concentrate, naming it Vitamin B12. In the same year, R. West confirmed its effectiveness in treating pernicious anemia through injections of Vitamin B12. The crystal structure of Vitamin B12 was determined in 1955 by D. Hodgkin using X-ray analysis, for which she won the 1964 Nobel Prize in Chemistry. In 1972, Woodward successfully synthesized Vitamin B12 in its entirety. Figure 1 is the source of vitamin B12
Chemical properties	Deep red crystal or powder, odorless and tasteless, absorbs moisture. Slightly soluble in water and ethanol, insoluble in chloroform or ether. Resistant to heat, but can become ineffective when exposed to oxidizing or reducing substances, heavy metals, strong acids, or alkalis.
The structure of vitamin B12	Vitamin B12 is an octahedral compound that contains cobalt ions. Its central structure is composed of a corrin ring connected to four pyrrole groups and a 5,6-dimethylbenzimidazole (DMBI) ligand. The cobalt ion is chelated to the Corrin ring by four nitrogen atoms. The DMBI ligand is linked to the cobalt ion through its N-7 atom and is further connected to a phosphate group, aminopropanol, and the propionic acid side chains of pyrrole D. The cobalt ion is also linked to adenosine or methyl groups as a beta ligand. Different forms of vitamin B12 have different axial ligands on the corrin ring. For example, hydroxyl (-OH) is connected to the cobalt ion to form hydroxocobalamin, deoxyadenosine forms deoxyadenosylcobalamin, methyl forms methylcobalamin, and cyano forms Vitamin B12e.
Uses	1.Vitamin B12 is a crucial nutrient that is necessary for the proper functioning of the human body. Its deficiency can lead to anemia and various nervous system disorders. 2.Vitamin B12 is primarily used in the treatment of megaloblastic anemia. It is also used to address poor nutrition, anemia due to blood loss, neuralgia, and obstructive disorders. 3.In the human body, vitamin B12 plays a crucial role in metabolism. The average total amount of vitamin B12 in the body is approximately 2-5mg, with the majority (50-90%) stored in the liver. 4.Vitamin B12, along with folic acid, is essential for the synthesis of nucleic acids during cell division. It is involved in the synthesis of purines, pyrimidines, nucleic acids, and methionine. In summary, vitamin B12 is primarily used to treat conditions such as pernicious anemia, megaloblastic anemia, anemia caused by antifolate drugs, and multiple neuritis. It is an essential nutrient for the proper functioning of the body, and its deficiency can lead to various health issues.
Physiologic function	1.Vitamin B12 plays a crucial role in the utilization of folic acid. It works in conjunction with folic acid to synthesize methionine and choline, which are important compounds involved in various processes such as purine and pyrimidine synthesis. 2.Vitamin B12 is essential for maintaining the metabolism and function of the nerve myelin sheath. Deficiency in vitamin B12 can result in neurological disorders, spinal cord degeneration, and severe psychiatric symptoms. It can also cause peripheral neuritis. 3. Vitamin B12 promotes the development and maturation of red blood cells. It is involved in the conversion of two acyl coenzyme A to succinate coenzyme A, which is crucial for the synthesis of the tricarboxylic acid cycle. 4.In addition to the aforementioned functions, Vitamin B12 also plays a role in the synthes

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—— Q&A ——

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

Q4:What if there are quality issues？

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

Certificates

Basic Info

Product Name:

Vitamin B12

Other Name:

Vitamin B12;Anacobin;Betalin 12;Betaline 12;Byladoce;Cobalin;Cotel;Covit;Crystamin;Cyano-B12;Cyanocobalamin;Cyanocobalamine;Cycolamin;Cykobeminet;Cytacon;Cytamen;Cytobion;5,6-Dimethylbenzimidazolyl cyanocobamide;Dobetin;Docemine;Docibin;Docigram;Dodecabee;Dodecavite;Dodex;Ducobee;Duodecibin;Embiol;Emociclina;Eritrone;Erycytol;Erythrotin;Euhaemon;Extrinsic factor;Fresmin;Hemo-b-doze;Hemomin;Hepagon;Hepavis;Hepcovite;Lactobacillus lactis dorner factor;LLD factor;Macrabin;Megalovel;Milbedoce;Nagravon;Normocytin;Pernaemon;Pernaevit;Pernipuron;Plecyamin;Poyamin;Rebramin;Redamina;Redisol;Rhodacryst;Rubesol;Rubramin;Rubripca;Rubrocitol;Sytobex;B-Twelve;B-Twelve Ora;Vibalt;Vibisone;Virubra;Vitarubin;Vita-rubra;Vitral;Cobalamin,cyanide;Cobalamin,cyano-;Cobamin;Cykobemin;Factor II (vitamin);Cobamide,α-5,6-dimethyl-1H-benzimidazolyl-,cyanide;1H-Benzimidazole,5,6-dimethyl-1-(3-O-phosphono-α-D-ribofuranosyl)-,monoester with cobinamide cyanide,inner salt;Cobamide,cyano-5,6-dimethyl-1H-benzimidazole-;Cyano-5,6-dimethylbenzimidazolylcobamide;5,6-Dimethylbenzimidazolyl-Co-cyanocobamide;Vitamin B12 preparation;Betolvex;Cobalamin,cyano-5,6-dimethylbenzimidazole-;CN-B12;Factor II;Depinar;Cobinamide,cyanide,dihydrogen phosphate (ester),inner salt,3′-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole;Hepavit;Docivit;Behepan;Bedoz;Berubigen;Antipernicin;Rubramin PC;Millevit;Berubi;8023-26-5;8039-03-0;11037-08-4;24436-34-8

CAS No.:

68-19-9

Molecular Formula:

C63H88CoN14O14P

InChIKeys:

InChIKey=FDJOLVPMNUYSCM-SYUKHSAKSA-L

Molecular Weight:

1355.37000

Exact Mass:

1354.57000

EC Number:

200-680-0

DSSTox ID:

DTXSID7044346

Color/Form:

Dark red crystals or an amorphous or crystalline red powder|Dark-red crystals or red powder

HScode:

2936260000

Categories:

Nutrition Supplements

Characteristics

PSA:

479.70000

XLogP3:

6.57018

Appearance:

red crystalline powder

Melting Point:

>300 °C

Boiling Point:

>300 °C

Flash Point:

48.2 °F

Water Solubility:

Soluble

Storage Conditions:

2-8ºC

Toxicity:

LD50 intravenous in mouse: 2gm/kg

Specific rotation:

SPECIFIC OPTICAL ROTATION: -59 + or - 9 DEG @ 23 °C 656 NM (DILUTE AQ SOLN)

Odor:

Odorless

Taste:

Tasteless

PH:

Commercially available cyanocobalamin for injection has a pH of 4.5-7

Experimental Properties:

Hygroscopic; when exposed to air, may absorb about 12% water; darkens at 210-220 °C; not melted at 300 °C|All vitamin B12 compounds contain the cobalt atom in its trivalent state. There are at least three active forms: cyanobalamin, hydroxycyanobalamin; nitrocobalamin

See More Vitamin B12 Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Vitamin B12 Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

53 Inquiries

Country	Product	Purchase Quantity	Date Posted
Paraguay	Vitamin B12	3.00 KG	Dec 1, 2025
United States	Vitamin B12 USP Cyanocobalamin Powder	75 KG	Feb 11, 2025
United States	Cyanocobalamin (Vitamin B12), Food Grade	200 KG	Jul 9, 2026
India	Vitamin B 12	100.00 KG	Jul 18, 2025
Turkey	SIYANOKOBALAMIN (VİTAMİN B12, CRYSTALLINE)	1.00 KG	Apr 16, 2025
India	Plant based vitamin b12	50.00 KG	Mar 25, 2025
India	CYNOCOBALMINE	10 KG	Aug 13, 2024
India	CYNOCOBALMINE	25 KG	Aug 12, 2024
India	Vitamin B12	500 KG	Aug 5, 2024
South Korea	cyanocobalamin B12	10 KG	Jul 11, 2024
Ecuador	Vitamin B12	100 KG	Feb 1, 2024
India	Vitamin B12	11.00 KG	Apr 25, 2025
India	VITAMIN B12	100 KG	Mar 12, 2025
India	Vitamin B12	1 KG	Jan 9, 2025
India	Cynocobalamine	25 G	Jan 7, 2025
United States	Vitamin B12	175 KG	Jul 3, 2024
Poland	Cyanocobalamin Powder	1 KG	Jun 25, 2024
United States	Vitamin B12	200 KG	Jun 14, 2024
Palestine	Vitamin B12	100 KG	May 22, 2024
United Arab Emirates	Vitamin B12	1 MT	Apr 1, 2024

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Vitamin B12 68-19-9 C63H88CoN14O14P

Product Description

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