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high quality novel potent inhibitor of HIV-1 integrase Bictegravir GS-9883 powder

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CAS No.:

1611493-60-7

Grade:

Pharmaceutical Grade

Content:

99%

Port:

qingdao

Brand:

Packaging:

Aluminium foil bag etc 1-10g,kg

Price valid (until):

2026-01-08

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NATURE INDUSTRIAL LIMITED

Company Type:

Trader

Location:

Hongkong, China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

7 days

Qualification:

Main Products:

Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

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Product Description
Seller Information

Description

API raw material powder Bictegravir CAS：1611493-60-7 HIV cure

Product Name: Bictegravir
Synonyms: Bictegravir;GS-9883;
CAS: 1611493-60-7
MF: C21H18F3N3O5
MW: 449.38
Bictegravir appearance
color: White to Off-White
Bictegravir Uses Bictegravir, is a novel, potent inhibitor of HIV-1 integrase.

Bictegravir Purity

Items Specifications

color off-white or white

purity 99%min

water solubility soluble in DMSO

Bictegravir package:

1g,50g,100g,500g,1kg,5kg,10kg,25kg per package

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our company

NATURE INDUSTRIAL LIMITED is a chemical company located in Jinan, Shandong Provincin Hongkong, China. The company was established in 20111 and has since grown to become a leading manufacturer and supplier of pharmaceutical intermediates, APIs, and other fine chemicals.

Quality is of the utmost importance to us The company has implemented a strict quality control system to ensure that all of its products meet or exceed the highest international standards. The company's quality control department is responsible for testing and analyzing each batch of products to ensure that they are of the highest quality.

NATURE INDUSTRIAL LIMITED is committed to environmental protection and sustainability. The company has implemented a comprehensive environmental management system that is in compliance with ISO 14001 standards. The company's production processes are designed to minimize waste and reduce the use of energy and other resources.

We are at exhibitions.We have established good cooerpation with customers from worldwide.

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our company in exhibition

ECHEMI Editorial Reference

Bictegravir (BIC) is a second-generation integrase strand transfer inhibitor (InSTI), like dolutegravir, with higher genetic barrier to resistance than raltegravir and elvitegravir.Bictegravir is a human immunodeficiency virus (HIV) integrase strand transfer inhibitor, the fourth in this class of agents that target the viral integrase. Bictegravir is used only in combination with other antiretroviral agents in the treatment of HIV infection and it has had limited use. Bictegravir is associated with a low rate of serum aminotransferase elevations during therapy, but has not been linked to instances of acute, clinically apparent liver injury.
ChEBI: Bictegravir is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2R,5S,13aR)-8-hydroxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic acid with the amino group of 2,4,6-trifluorobenzylamine. It is a second-generation integrase strand transfer inhibitor (INSTI) and used (as its sodium salt) for the treatment of HIV-1. It has a role as a HIV-1 integrase inhibitor. It is a monocarboxylic acid amide, a secondary carboxamide, a trifluorobenzene and an organic heterotetracyclic compound. It is a conjugate acid of a bictegravir(1-).

Basic Info

Product Name:
Bictegravir

Other Name:
Bictegravir;GS-9883;(2R,5S,13aR)-2,3,4,5,7,9,13,13a-Octahydro-8-hydroxy-7,9-dioxo-N-[(2,4,6-trifluorophenyl)methyl]-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide;Bictegravir (GS-9883);(2R,5S,13aR)-8-hydroxy-7,9-dioxo-N-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide;BNKY010-BC03;BICTEGRAVIR;GS-9883;GS 9883;GS9883;(2R,5S,13aR)-8-hydroxy-7,9-dioxo-N-(2,4,6-trifluorobenzyl)

CAS No.:
1611493-60-7

Molecular Formula:
C21H18F3N3O5

InChIKeys:
SOLUWJRYJLAZCX-LYOVBCGYSA-N

Molecular Weight:
449.38

Exact Mass:
449.38

Color/Form:
White to Off-White

Categories:
Inhibitor Drugs

Characteristics

PSA:
100.87

XLogP3:
1.9632

Density:
1.62±0.1 g/cm3(Predicted)

Melting Point:
>130°C (dec.)

Boiling Point:
682.5±55.0 °C(Predicted)

PKA:
4.50±1.00(Predicted)

Critical Temperature & Pressure:
Sealed in dry,Store in freezer, under -20°C

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Seller Information

Business Type:
Trader

Main Products:
Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

Location:
Unit D01,3/F., Wong King Industrial Building,No.2 Tai Yau Street, Kowloon

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7 days

Total Annual Revenue:
$50 million-$100 million

Total Employees:
51-100

Year of Establishment:
2012

We have more than 10 years experience in the pharmacy filed. Mainly manufactures pharmaceutical APIs,Pharmaceutical intermediate and Cosmetic raw material. Owing to the good quality and competitive price, we have a very good reputation in China's pharmaceutical circles.

In the principle of "Quality Oriented", Jianfeng passed the certification of ISO9001:2008 Quality Management System.

Our products are based on bulk, high volume, wholesale price, third party testing, certificate reporting, and bring high quality ingredients to many domestic and overseas enterprises.

"Honesty, practicality, innovation, development" are our values. Jianfeng would like to cooperate with you with high quality products and competitive price.
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high quality novel potent inhibitor of HIV-1 integrase Bictegravir GS-9883 powder

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Items	Specifications
color	off-white or white
purity	99%min
water solubility	soluble in DMSO