API raw material powder novel potent inhibitor of HIV-1 integrase GS-9883 GS9883 Bictegravir CAS 1611493-60-8
1611493-60-7
Pharmaceutical Grade
99%
QINGDAO
JF
Aluminium foil bag etc 1-10g,kg
2026-01-08
Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceBictegravir (BIC) is a second-generation integrase strand transfer inhibitor (InSTI), like dolutegravir, with higher genetic barrier to resistance than raltegravir and elvitegravir.Bictegravir is a human immunodeficiency virus (HIV) integrase strand transfer inhibitor, the fourth in this class of agents that target the viral integrase. Bictegravir is used only in combination with other antiretroviral agents in the treatment of HIV infection and it has had limited use. Bictegravir is associated with a low rate of serum aminotransferase elevations during therapy, but has not been linked to instances of acute, clinically apparent liver injury.
ChEBI: Bictegravir is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2R,5S,13aR)-8-hydroxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic acid with the amino group of 2,4,6-trifluorobenzylamine. It is a second-generation integrase strand transfer inhibitor (INSTI) and used (as its sodium salt) for the treatment of HIV-1. It has a role as a HIV-1 integrase inhibitor. It is a monocarboxylic acid amide, a secondary carboxamide, a trifluorobenzene and an organic heterotetracyclic compound. It is a conjugate acid of a bictegravir(1-).Basic Info-
Product Name:
Bictegravir
Other Name:Bictegravir;GS-9883;(2R,5S,13aR)-2,3,4,5,7,9,13,13a-Octahydro-8-hydroxy-7,9-dioxo-N-[(2,4,6-trifluorophenyl)methyl]-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide;Bictegravir (GS-9883);(2R,5S,13aR)-8-hydroxy-7,9-dioxo-N-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide;BNKY010-BC03;BICTEGRAVIR;GS-9883;GS 9883;GS9883;(2R,5S,13aR)-8-hydroxy-7,9-dioxo-N-(2,4,6-trifluorobenzyl)
CAS No.:1611493-60-7
Molecular Formula:C21H18F3N3O5
InChIKeys:SOLUWJRYJLAZCX-LYOVBCGYSA-N
Molecular Weight:449.38
Exact Mass:449.38
Color/Form:White to Off-White
Categories:
Characteristics-
PSA:
100.87
XLogP3:1.9632
Density:1.62±0.1 g/cm3(Predicted)
Melting Point:>130°C (dec.)
Boiling Point:682.5±55.0 °C(Predicted)
PKA:4.50±1.00(Predicted)
Critical Temperature & Pressure:Sealed in dry,Store in freezer, under -20°C
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Seller Information
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Business Type:
Trader
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Main Products:
Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332
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Location:
Unit D01,3/F., Wong King Industrial Building,No.2 Tai Yau Street, Kowloon
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7
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Total Annual Revenue:
$50 million-$100 million
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Total Employees:
51-100
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Year of Establishment:
2012
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