1-Methylnicotinamide Chloride CAS No.:1005-24-9

1. 1、Product introduction

  1-Methylnicotinamide chloride is a methylated derivative of nicotinamide, characterized by a stable quaternary ammonium salt structure. It serves as a critical intermediate in studying nicotinamide metabolism. Its favorable water solubility and chemical stability render it suitable as a tool compound for biochemical research .

1-MNA is a naturally occurring substance in the human body, functioning as a normal downstream product of niacin metabolism. As an intermediate in this metabolic pathway, 1-MNA is further processed by aldehyde oxidase to generate downstream metabolites such as N-methyl-2-pyridone-5-carboxamide (2PY) and N-methyl-4-pyridone-3-carboxamide (4PY), which are eventually excreted through the urinary system .

1. 2、Feature

(1) ​Water solubility: Readily soluble in water and polar organic solvents .

(2) ​Stability: Stable under room temperature conditions but requires storage in moisture-proof environments .

(3) ​Safety: The European Union has conducted a scientific assessment of 1-MNA as a novel food ingredient. Pursuant to EU Regulation (EC) No 258/97, 1-MNA is deemed safe for consumption, with a recommended maximum adult daily intake of 58 mg, primarily intended for use in food supplements .

3、Applications

 1-Methylnicotinamide chloride (abbreviated as MNC) is a methylated derivative of nicotinamide. Detection of 1-MNA can be accomplished via methods like high-performance liquid chromatography (HPLC) and Infrared spectroscopy （IR spectroscopy）. It exhibits potential for applications within the food and health product sectors. In the food industry, it may act as an antioxidant to delay lipid oxidation and preserve food quality. Owing to its structural attributes, it can also serve as a functional ingredient in nutritionally fortified foods. Moreover, 1-MNA demonstrates activities in metabolic regulation and improvement of physiological states, lending it value for development in functional foods and dietary supplements bearing health claims .

The EU evaluation concluded that a daily intake of 58 mg of 1-MNA from food supplements is unlikely to lead to adverse health outcomes in humans, and it has been formally included in the EU novel food catalogue .

As a significant bioactive molecule and reference standard, 1-methylnicotinamide chloride holds broad application prospects in scientific research, pharmaceutical development, and the food supplement industry. Its well-defined safety evaluation and diverse biological activities establish it as a valuable subject for research and a component for various applications . 【Frequently Asked Questions】
【1】Q: What is your delivery time?
A: Generally 1~5 days after receiving payment.
【2】Q: Where is your shipping port?
A: Shanghai/Ningbo.
【3】Q: What is the specific form of packaging?
A: Usually our packaging is 1kg/bag and 25kg/barrel. Of course, if you have special
requirements, we will also package them according to your requirements.
【4】Q: Can your company accept customization and meet customers' specific specifications?
A: Yes, we can.
【5】Q: Can your company provide samples?
A: Yes, we can, please contact us by phone for specific sample information.