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Nonivamide CAS:2444-46-4

Name: Nonivamide CAS:2444-46-4
Brand: Orient
SKU: pr2512231373
Price: 4 USD
Availability: InStock

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CAS No.:

2444-46-4

Grade:

Industrail Grade

Content:

99%

Port:

SHANGHAI

Brand:

Orient

Packaging:

25L, 200L, 1000L, customized

Price valid (until):

2026-01-23

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

Product Name:	Nonivamide
Synonyms:	Nonivamide(Synthetic Capsaicin);N-((Hydroxy-3-methoxyphenyl)methyl)4-nonanamide;N-Nonanoyl vanillylamide;Nonanamide, N-((4-hydroxy-3-methoxyphenyl)meth;SYNTHETIC CAPSAICIN;PELARGONYL VANILLYLAMIDE;PELARGONIC ACID VANILLYLAMIDE;N-PELARGONIC ACID VANILLYLAMIDE
CAS:	2444-46-4
MF:	C17H27NO3
MW:	293.4
EINECS:	219-484-1
Product Categories:	Anilines, Aromatic Amines and Nitro Compounds;INORGANIC & ORGANIC CHEMICALS;Plant extract;Herb extract;Inhibitors;API;2444-46-4
Mol File:	2444-46-4.mol

Nonivamide Chemical Properties

Melting point	54°C
Boiling point	200-210 °C(Press: 0.05 Torr)
density	1,1 g/cm³
FEMA	2787 \| NONANOYL 4-HYDROXY-3-METHOXYBENZYLAMIDE
Fp	190°C
storage temp.	Sealed in dry,2-8°C
solubility	methanol: 100 mg/mL, clear to slightly hazy
form	powder
pka	9.76±0.20(Predicted)
color	white to off-white
Odor	bland odorless
Odor Type	bland
JECFA Number	1599
BRN	2144300
Stability:	Stable. Incompatible with strong oxidizing agents.
Cosmetics Ingredients Functions	FRAGRANCE
InChIKey	RGOVYLWUIBMPGK-UHFFFAOYSA-N
LogP	3.43
CAS DataBase Reference	2444-46-4(CAS DataBase Reference)
EPA Substance Registry System	Nonanamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]- (2444-46-4)

Safety Information

Hazard Codes	T,Xi
Risk Statements	25-36/37/38-43
Safety Statements	26-45-37/39-36/37
RIDADR	UN 3462 6.1/PG 2
WGK Germany	3
RTECS	RA5998000
F	19
HazardClass	6.1
PackingGroup	II
HS Code	29242990
Toxicity	mouse,LD50,intraperitoneal,8mg/kg (8mg/kg),Journal of Medicinal Chemistry. Vol. 36, Pg. 2595, 1993.

MSDS Information

Nonivamide Usage And Synthesis

Description	Nonivamide is also called pelargonic acid vanillylamide or PAVA. It is a capsaicinoid. Nonivamide, isolated from peppers, is a naturally occurring analog of capsaicin (sc-3577). Similar to capsaicin, nonivamide can activate the TRPV1 receptor, thus, stimulate the firing rate of dopaminergic neurons in the ventral tegmental area of the brain and to increase the expression of the serotonin receptor gene HTR2A. Nonivamide is with lower TRPV1 binding affinity, thus, a reduced pungency (9 200 000 scoville heat units) compared to capsaicin (16 000 000 scoville heat units). Nonivamide is used in the food production to add a hot sensation to flavoring agents and spice mixtures. It is also used in the sweets and confectionary industries to add hot sensation into products. In pharmaceutical industries, nonivamide is used as a cheaper alternative for capsaicin. Warming or heating ointment of nonivamide is used for temporary relief of pain from conditions such as rheumatism, arthritis, lumbao, muscular aches, sprains and strains, sporting injuries and other conditions where local warmth is beneficial. Finalgon is one of the common product utilizing nonivamide for this purpose. Nonivamide is also used as an incapacitant spray, affecting the assailed person’s eyes, causing intense pain and swelling.
References	[1] https://www.scbt.com/scbt/product/nonivamide-2444-46-4 [2] https://pubchem.ncbi.nlm.nih.gov/compound/N-Vanillylnonanamide#section=Clinical-Trials [3] https://cot.food.gov.uk/sites/default/files/cot/cotsection.pdf
Description	Nonanoyl-4-hydroxy-3-methoxybenzylamide is odorless with a pungent, burning taste. Synthesized from nonanyl chloride and vanillylamine.
Chemical Properties	n-Nonanyl-4-hydroxy-3-methoxybenzyl-amide is an odorless compound, but has a pungent, burning taste
Chemical Properties	solid
Uses	analgesic (topical), depletes Substance P
Uses	N-Vanillylnonanamide is a synthetic analogue of Capsaicin (175680) with similar bioactivity.

First aid measures

If inhaled

Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.

Following skin contact

Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.

Following eye contact

Rinse with pure water for at least 15 minutes. Consult a doctor.

Following ingestion

Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.

Accidental release measures

Personal precautions, protective equipment and emergency procedures

Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak. Environmental precautions

Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

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—— Q&A ——

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

Q4:What if there are quality issues？

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

Certificates

Basic Info

Product Name:

Nonivamide

Other Name:

Nonanamide,N-[(4-hydroxy-3-methoxyphenyl)methyl]-;Nonanamide,N-vanillyl-;N-[(4-Hydroxy-3-methoxyphenyl)methyl]nonanamide;Nonanoic acid vanillylamide;Pelargonic acid vanillylamide;N-Vanillylnonanamide;N-Vanillylpelargonamide;Vanillyl n-nonylamide;Vanillyl pelargonic amide;N-Vanillylnonamide;Nonylic acid vanillylamide;Nonylic vanillylamide;Nonivamide;AH 23491X;Pseudocapsaicin;N-(4-Hydroxy-3-methoxybenzyl)nonamide;Nonanoylvanillyl amide;8-Nordihydrocapsaicin;NSC 172795;618-92-8;60806-29-3;497080-86-1

CAS No.:

2444-46-4

Molecular Formula:

C17H27NO3

InChIKeys:

InChIKey=RGOVYLWUIBMPGK-UHFFFAOYSA-N

Molecular Weight:

293.40100

Exact Mass:

293.40

EC Number:

219-484-1

UNII:

S846B891OR

NSC Number:

760391|172795

DSSTox ID:

DTXSID1034769

HScode:

2924299090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

58.56000

XLogP3:

4.2

Appearance:

Solid

Density:

1.037 g/cm3

Melting Point:

57-59 °C

Boiling Point:

200-210 °C @ Press: 0.05 Torr

Flash Point:

251.8ºC

Refractive Index:

1.513

Water Solubility:

soluble in water (slightly)

Storage Conditions:

2-8ºC

Vapor Pressure:

2.48E-10mmHg at 25°C

PKA:

9.77None

Dissociation Constants:

9.77

See More Nonivamide Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 3, Oral

Skin irritation, Category 2

Skin sensitization, Category 1

Serious eye damage, Category 1

Respiratory sensitization, Category 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H301 Toxic if swallowed H315 Causes skin irritation H317 May cause an allergic skin reaction H318 Causes serious eye damage H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P284 [In case of inadequate ventilation] wear respiratory protection.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P333+P317 If skin irritation or rash occurs: Get medical help. P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P317 Get medical help. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P342+P316 If experiencing respiratory symptoms: Get emergency medical help immediately.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Nonivamide Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

7 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Nonivamide	500 KG	Feb 19, 2024
India	Nonivamide	100 G	Jun 10, 2026
Canada	99% Synthetic Capsaicin Nonivamide Powder	1 G	Jul 7, 2025
Netherlands	nonivamide	1 KG	Jun 20, 2025
India	nonivamide	5 KG	Mar 13, 2024
United States	Nonivamide	1 KG	Jan 31, 2025
Russia	Nonivamide	5 KG	Dec 19, 2024

Post an enquiry for this product

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